Cerebral sparganosis in a child with corpus callosum invasion: a case report.
Child
Corpus callosum
Magnetic resonance imaging
Migration mode
Parasitic diseases
Sparganosis
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
25 May 2023
25 May 2023
Historique:
received:
02
02
2023
accepted:
11
05
2023
medline:
29
5
2023
pubmed:
26
5
2023
entrez:
25
5
2023
Statut:
epublish
Résumé
Invasion of the corpus callosum by sparganosis is rare in children. After invading the corpus callosum, sparganosis has various migration modes, which can break through the ependyma and enter the ventricles, thus causing secondary migratory brain injury. A girl aged 4 years and 7 months presented with left lower limb paralysis for more than 50 days. Blood examination showed that the proportion and absolute number of eosinophils in the peripheral blood were increased. Furthermore, enzyme-linked immunosorbent assay of serum and cerebrospinal fluid samples revealed positivity for IgG and IgM antibodies for sparganosis. Initial magnetic resonance imaging (MRI) revealed ring-like enhancements in the right frontoparietal cortex, subcortical white matter, and splenium of the corpus callosum. Within 2 months, a fourth follow-up MRI showed that the lesion had spread to the left parietal cortex, subcortical white matter, and deep white matter in the right occipital lobe and right ventricular choroid plexus, with left parietal leptomeningeal enhancement. Migratory movement is one of the characteristics of cerebral sparganosis. When sparganosis invades the corpus callosum, clinicians should be aware that it may then break through the ependyma and enter the lateral ventricles, leading to secondary migratory brain injury. Short-term follow-up MRI is necessary to evaluate the migration mode of sparganosis and dynamically guide treatment strategies.
Sections du résumé
BACKGROUND
BACKGROUND
Invasion of the corpus callosum by sparganosis is rare in children. After invading the corpus callosum, sparganosis has various migration modes, which can break through the ependyma and enter the ventricles, thus causing secondary migratory brain injury.
CASE PRESENTATION
METHODS
A girl aged 4 years and 7 months presented with left lower limb paralysis for more than 50 days. Blood examination showed that the proportion and absolute number of eosinophils in the peripheral blood were increased. Furthermore, enzyme-linked immunosorbent assay of serum and cerebrospinal fluid samples revealed positivity for IgG and IgM antibodies for sparganosis. Initial magnetic resonance imaging (MRI) revealed ring-like enhancements in the right frontoparietal cortex, subcortical white matter, and splenium of the corpus callosum. Within 2 months, a fourth follow-up MRI showed that the lesion had spread to the left parietal cortex, subcortical white matter, and deep white matter in the right occipital lobe and right ventricular choroid plexus, with left parietal leptomeningeal enhancement.
CONCLUSION
CONCLUSIONS
Migratory movement is one of the characteristics of cerebral sparganosis. When sparganosis invades the corpus callosum, clinicians should be aware that it may then break through the ependyma and enter the lateral ventricles, leading to secondary migratory brain injury. Short-term follow-up MRI is necessary to evaluate the migration mode of sparganosis and dynamically guide treatment strategies.
Identifiants
pubmed: 37231358
doi: 10.1186/s12879-023-08322-9
pii: 10.1186/s12879-023-08322-9
pmc: PMC10210387
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
350Subventions
Organisme : The Research Foundation of Medical Science and Technology of Guangdong Province
ID : A2021261
Organisme : The Research Foundation of Medical Science and Technology of Guangdong Province
ID : A2021261
Organisme : The Research Foundation of Medical Science and Technology of Guangdong Province
ID : A2021261
Organisme : The Research Foundation of Medical Science and Technology of Guangdong Province
ID : A2021261
Organisme : The Research Foundation of Medical Science and Technology of Guangdong Province
ID : A2021261
Organisme : The Research Foundation of Medical Science and Technology of Guangdong Province
ID : A2021261
Informations de copyright
© 2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.
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