Formation of Amorphous Iron-Calcium Phosphate with High Stability.

ammonium iron citrates amorphous calcium phosphates biomineralizations phase transformations

Journal

Advanced materials (Deerfield Beach, Fla.)
ISSN: 1521-4095
Titre abrégé: Adv Mater
Pays: Germany
ID NLM: 9885358

Informations de publication

Date de publication:
Aug 2023
Historique:
revised: 05 05 2023
received: 14 02 2023
medline: 18 8 2023
pubmed: 26 5 2023
entrez: 26 5 2023
Statut: ppublish

Résumé

Amorphous iron-calcium phosphate (Fe-ACP) plays a vital role in the mechanical properties of teeth of some rodents, which are very hard, but its formation process and synthetic route remain unknown. Here, the synthesis and characterization of an iron-bearing amorphous calcium phosphate in the presence of ammonium iron citrate (AIC) are reported. The iron is distributed homogeneously on the nanometer scale in the resulting particles. The prepared Fe-ACP particles can be highly stable in aqueous media, including water, simulated body fluid, and acetate buffer solution (pH 4). In vitro study demonstrates that these particles have good biocompatibility and osteogenic properties. Subsequently, Spark Plasma Sintering (SPS) is utilized to consolidate the initial Fe-ACP powders. The results show that the hardness of the ceramics increases with the increase of iron content, but an excess of iron leads to a rapid decline in hardness. Calcium iron phosphate ceramics with a hardness of 4 GPa can be achieved, which is higher than that of human enamel. Furthermore, the ceramics composed of iron-calcium phosphates show enhanced acid resistance. This study provides a novel route to prepare Fe-ACP, and presents the potential role of Fe-ACP in biomineralization and as starting material to fabricate acid-resistant high-performance bioceramics.

Identifiants

pubmed: 37232047
doi: 10.1002/adma.202301422
doi:

Substances chimiques

amorphous calcium phosphate 0
Iron E1UOL152H7
calcium phosphate 97Z1WI3NDX
Calcium Phosphates 0
Calcium SY7Q814VUP

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2301422

Subventions

Organisme : National Natural Science Foundation of China
ID : 82002275
Organisme : National Natural Science Foundation of China
ID : 32271421
Organisme : National Natural Science Foundation of China
ID : 81925027
Organisme : Natural Science Foundation of the Jiangsu Higher Education Institutions of China
ID : 20KJB430041
Organisme : Priority Academic Program Development of Jiangsu Higher Education Institutions

Informations de copyright

© 2023 The Authors. Advanced Materials published by Wiley-VCH GmbH.

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Auteurs

Song Chen (S)

Orthopedic Institute, Department of Orthopaedic Surgery, The First Affiliated Hospital, School of Biology & Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215006, P. R. China.

Dachuan Liu (D)

Orthopedic Institute, Department of Orthopaedic Surgery, The First Affiliated Hospital, School of Biology & Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215006, P. R. China.

Le Fu (L)

School of Materials Science and Engineering, Central South University, Changsha, 410017, P. R. China.

Bing Ni (B)

Physical Chemistry, Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457, Konstanz, Germany.

Zongkun Chen (Z)

Physical Chemistry, Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457, Konstanz, Germany.

Jennifer Knaus (J)

Physical Chemistry, Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457, Konstanz, Germany.

Elena V Sturm (EV)

Physical Chemistry, Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457, Konstanz, Germany.
Section Crystallography, Department of Geo- and Environmental Sciences, Ludwigs-Maximilians-University Munich, Theresienstr. 41, 80333, Munich, Germany.

Bohan Wang (B)

School of Materials Science and Engineering, Central South University, Changsha, 410017, P. R. China.

Håvard Jostein Haugen (HJ)

Department of Biomaterials, Institute for Clinical Dentistry, University of Oslo, PO Box 1109 Blindern, Oslo, 0376, Norway.

Hongji Yan (H)

Department of Medical Cell Biology, Uppsala University, Uppsala, 752 36, Sweden.
AIMES - Center for the Advancement of Integrated Medical and Engineering Sciences at Karolinska Institutet and KTH Royal Institute of Technology, Stockholm, 171 77, Sweden.
Department of Neuroscience, Karolinska Institutet, Stockholm, 171 77, Sweden.

Helmut Cölfen (H)

Physical Chemistry, Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457, Konstanz, Germany.

Bin Li (B)

Orthopedic Institute, Department of Orthopaedic Surgery, The First Affiliated Hospital, School of Biology & Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215006, P. R. China.
Collaborative Innovation Center of Hematology, Soochow University, Suzhou, Jiangsu, 215006, P.R.China.
Department of Orthopaedic Surgery, The Affiliated Haian Hospital of Nantong University, Haian,Nantong, Jiangsu, 226600, P.R.China.

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