Investigating the antiviral therapeutic potentialities of marine polycyclic lamellarin pyrrole alkaloids as promising inhibitors for SARS-CoV-2 and Zika main proteases (Mpro).

SARS-CoV-2 Zika virus antiviral dynamics simulation lamellarins alkaloids marine sponges molecular docking

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
26 May 2023
Historique:
medline: 26 5 2023
pubmed: 26 5 2023
entrez: 26 5 2023
Statut: aheadofprint

Résumé

The new coronavirus variant (SARS-CoV-2) and Zika virus are two world-wide health pandemics. Along history, natural products-based drugs have always crucially recognized as a main source of valuable medications. Considering the SARS-CoV-2 and Zika main proteases (

Identifiants

DOI: 10.1080/07391102.2023.2217513 PMID: 37232419
pubmed: 37232419
doi: 10.1080/07391102.2023.2217513
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-19

Auteurs

Florbela Pereira (F)

LAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade Nova de Lisboa, Caparica, Portugal.

Loay Bedda (L)

Drug Design and Discovery Laboratory, Helmy Institute for Medical Sciences, Zewail City of Science and Technology, Giza, Egypt.
Biomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Giza, Egypt.

Mohamed A Tammam (MA)

Department of Biochemistry, Faculty of Agriculture, Fayoum University, Fayoum, Egypt.

Abdul Kader Alabdullah (AK)

Crop Genetics Department, John Innes Centre, Colney, Norwich, UK.

Reem Arafa (R)

Drug Design and Discovery Laboratory, Helmy Institute for Medical Sciences, Zewail City of Science and Technology, Giza, Egypt.
Biomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Giza, Egypt.

Amr El-Demerdash (A)

Division of Organic Chemistry, Department of Chemistry, Faculty of Sciences, Mansoura University, Mansoura, Egypt.
Department of Biochemistry and Metabolism, the John Innes Centre, Norwich Research Park, Norwich, UK.

Classifications MeSH