Radiation Exposure Reduction by Digital Variance Angiography in Lower Limb Angiography: A Randomized Controlled Trial.

digital subtraction angiography digital variance angiography lower limb angiography peripheral artery disease radiation protection radiation reduction

Journal

Journal of cardiovascular development and disease
ISSN: 2308-3425
Titre abrégé: J Cardiovasc Dev Dis
Pays: Switzerland
ID NLM: 101651414

Informations de publication

Date de publication:
30 Apr 2023
Historique:
received: 19 03 2023
revised: 24 04 2023
accepted: 28 04 2023
medline: 26 5 2023
pubmed: 26 5 2023
entrez: 26 5 2023
Statut: epublish

Résumé

digital variance angiography (DVA) provides higher image quality than digital subtraction angiography (DSA). This study investigates whether the quality reserve of DVA allows for radiation dose reduction during lower limb angiography (LLA), and compares the performance of two DVA algorithms. this prospective block-randomized controlled study enrolled 114 peripheral arterial disease patients undergoing LLA into normal dose (ND, 1.2 µGy/frame, the total and DSA-related DAP were reduced by 38% and 61% in the LD group. The overall visual evaluation scores (median (IQR)) of LD-DSA (3.50 (1.17)) were significantly lower than the ND-DSA scores (3.83 (1.00), DVA significantly reduced the total and DSA-related radiation dose in LLA, without affecting the image quality. LD-DVA2 images outperformed LD-DVA1, therefore DVA2 might be especially beneficial in lower limb interventions.

Sections du résumé

BACKGROUND BACKGROUND
digital variance angiography (DVA) provides higher image quality than digital subtraction angiography (DSA). This study investigates whether the quality reserve of DVA allows for radiation dose reduction during lower limb angiography (LLA), and compares the performance of two DVA algorithms.
METHODS METHODS
this prospective block-randomized controlled study enrolled 114 peripheral arterial disease patients undergoing LLA into normal dose (ND, 1.2 µGy/frame,
RESULTS RESULTS
the total and DSA-related DAP were reduced by 38% and 61% in the LD group. The overall visual evaluation scores (median (IQR)) of LD-DSA (3.50 (1.17)) were significantly lower than the ND-DSA scores (3.83 (1.00),
CONCLUSIONS CONCLUSIONS
DVA significantly reduced the total and DSA-related radiation dose in LLA, without affecting the image quality. LD-DVA2 images outperformed LD-DVA1, therefore DVA2 might be especially beneficial in lower limb interventions.

Identifiants

pubmed: 37233165
pii: jcdd10050198
doi: 10.3390/jcdd10050198
pmc: PMC10219428
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : National Research, Development and Innovation Office of Hungary
ID : 2020-1.1.5-GYORSÍTÓSÁV-2021-00018
Organisme : European Commission EIC Accelerator Pilot Grant
ID : 968430 KMIT-ACC
Organisme : National Research, Development and Innovation Office of Hungary
ID : NVKP-16-1-2016-0017 National Heart Program
Organisme : Ministry of Innovation and Technology of Hungary
ID : Thematic Excellence Program (2020-4.1.1.-TKP2020)

Références

J Vasc Interv Radiol. 2022 Feb;33(2):104-112
pubmed: 34653607
Cardiovasc Intervent Radiol. 2020 Aug;43(8):1226-1231
pubmed: 32476034
Am J Cardiol. 2013 May 1;111(9):1368-72
pubmed: 23419190
Cardiovasc Intervent Radiol. 2021 Jun;44(6):842-848
pubmed: 33034703
Cardiovasc Intervent Radiol. 2021 Jun;44(6):871-876
pubmed: 33837456
AJR Am J Roentgenol. 2016 Oct;207(4):745-754
pubmed: 27440524
JACC Cardiovasc Interv. 2013 Oct;6(10):1095-102
pubmed: 24156970
Radiology. 2010 Nov;257(2):321-32
pubmed: 20959547
Eur J Vasc Endovasc Surg. 2020 Apr;59(4):654-660
pubmed: 32061447
Eur J Vasc Endovasc Surg. 2019 Jul;58(1S):S1-S109.e33
pubmed: 31182334
JACC Cardiovasc Interv. 2019 Mar 11;12(5):473-480
pubmed: 30846087
J Stroke. 2022 May;24(2):207-223
pubmed: 35677976
Invest Radiol. 2019 Jul;54(7):428-436
pubmed: 30829769
IEEE Trans Med Imaging. 2014 Oct;33(10):2031-8
pubmed: 24951684
Invest Radiol. 2019 Mar;54(3):153-159
pubmed: 30444795
Radiology. 2018 Feb;286(2):592-601
pubmed: 29019450
World J Diabetes. 2021 Dec 15;12(12):2011-2026
pubmed: 35047116
Radiology. 2019 Mar;290(3):744-749
pubmed: 30644807
Radiology. 2019 Jan;290(1):246-253
pubmed: 30325284
Acad Radiol. 2023 Apr;30(4):689-697
pubmed: 35688786
Cardiovasc Intervent Radiol. 2023 May;46(5):635-642
pubmed: 37076552
J Am Coll Cardiol. 2022 Jul 12;80(2):155-170
pubmed: 35798450
Cardiovasc Intervent Radiol. 2021 Mar;44(3):452-459
pubmed: 33145701
Eur J Vasc Endovasc Surg. 2020 Feb;59(2):173-218
pubmed: 31899099
Sci Rep. 2021 Nov 8;11(1):21790
pubmed: 34750427
Eur J Radiol Open. 2020 Nov 17;7:100288
pubmed: 33294499

Auteurs

Péter Sótonyi (P)

Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.

Márton Berczeli (M)

Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.
Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.

Marcell Gyánó (M)

Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.
Department of Interventional Radiology, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.

Péter Legeza (P)

Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.
Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.

Zsuzsanna Mihály (Z)

Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.
Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.

Csaba Csobay-Novák (C)

Department of Interventional Radiology, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.

Ákos Pataki (Á)

Department of Interventional Radiology, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.

Viktória Juhász (V)

Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.

István Góg (I)

Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.
Department of Vascular Surgery, Hungarian Defence Forces Medical Centre, Róbert Károly körút 44, 1134 Budapest, Hungary.

Krisztián Szigeti (K)

Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.
Department of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary.

Szabolcs Osváth (S)

Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.
Department of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary.

János P Kiss (JP)

Kinepict Health Ltd., Szilágyi Erzsébet Fasor 31, 1027 Budapest, Hungary.
Department of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary.

Balázs Nemes (B)

Department of Interventional Radiology, Heart and Vascular Center, Semmelweis University, Városmajor utca 68, 1122 Budapest, Hungary.

Classifications MeSH