Chronic Progressive Lymphedema in Belgian Draft Horses: Understanding and Managing a Challenging Disease.
Belgian draft horse
clinical signs
elastin
fibrosis
hyperkeratosis
lymphedema
pathogenesis
skinfolds
treatment
Journal
Veterinary sciences
ISSN: 2306-7381
Titre abrégé: Vet Sci
Pays: Switzerland
ID NLM: 101680127
Informations de publication
Date de publication:
12 May 2023
12 May 2023
Historique:
received:
03
04
2023
revised:
27
04
2023
accepted:
09
05
2023
medline:
26
5
2023
pubmed:
26
5
2023
entrez:
26
5
2023
Statut:
epublish
Résumé
Chronic progressive lymphedema (CPL) in draft horses is characterized by increased dermal thickness and fibrosis, with the development of skinfolds and nodules, hyperkeratosis, and ulcerations on the distal limbs of affected horses. Secondary bacterial, fungal, or parasitic infections frequently complicate and aggravate the lesions, as well as the progression of this disease. CPL has a particularly high prevalence of up to 85.86% in the Belgian draft horse breed. Due to the disease's progressive and incurable nature, affected horses are often euthanized prematurely. The treatment options are solely symptomatic, aimed at improving the horse's quality of life. Despite the severity of this condition, many uncertainties about its etiology and pathogenesis still remain to date. The established scientific research on CPL is rather limited, although there is an urgent need for strategies to tackle this disease. This review summarizes the available knowledge, serving as a guideline for practitioners, and provides perspectives for future research programs.
Identifiants
pubmed: 37235431
pii: vetsci10050347
doi: 10.3390/vetsci10050347
pmc: PMC10222719
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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