The Impact of Lumbopelvic Realignment versus Prevention Strategies at the Upper-Instrumented Vertebra on Rates of Junctional Failure following Adult Spinal Deformity Surgery.
Journal
Spine
ISSN: 1528-1159
Titre abrégé: Spine (Phila Pa 1976)
Pays: United States
ID NLM: 7610646
Informations de publication
Date de publication:
26 May 2023
26 May 2023
Historique:
received:
21
10
2022
accepted:
06
02
2023
medline:
26
5
2023
pubmed:
26
5
2023
entrez:
26
5
2023
Statut:
aheadofprint
Résumé
Differing presentations of adult spinal deformity(ASD) may influence the extent of surgical intervention and use of prophylaxis at the base or the summit of a fusion construct to influence junctional failure rates. Evaluate the surgical technique that has greatest influence on the rate of junctional failure following ASD surgery. Retrospective. ASD patients with two-year(2Y) data and at least 5-level fusion to pelvis were included. Patients were divided based on UIV: [Longer Construct:T1-T4; Shorter Construct:T8-T12]. Parameters assessed included matching in age-adjusted PI-LL or PT, aligning in GAP-Relative Pelvic Version or Lordosis Distribution Index. After assessing all lumbopelvic radiographic parameters, the combination of realigning the two parameters with the greatest minimizing effect of PJF constituted a Good Base. Good Summit defined as having: (1)prophylaxis at UIV(tethers,hooks,cement), (2)no lordotic change(under-contouring) greater than 10° of the UIV, (3)preoperative UIV inclination angle<30°. Multivariable regression analysis assessed effects of junction characteristics and radiographic correction individually and collectively on development of PJK and PJF in differing construct lengths, adjusting for confounders. 261 patients were included. The cohort had lower odds of PJK(OR: 0.5,[0.2-0.9];P=0.044) and PJF was less likely (OR: 0.1,[0.0-0.7];P=0.014) in the presence of a Good Summit. Normalizing pelvic compensation had the greatest radiographic effect on preventing PJF overall (OR: 0.6,[0.3-1.0];P=0.044). In Shorter Constructs, realignment had greater effect on decreasing the odds of PJF(OR: 0.2,[0.02-0.9];P=0.036). With Longer Constructs, a Good Summit lowered likelihood of PJK(OR: 0.3,[0.1-0.9];P=0.027). Good Base led to zero occurrences of PJF. In patients with severe frailty/osteoporosis, a Good Summit lowered incidence of PJK(OR: 0.4,[0.2-0.9]; P=0.041) and PJF (OR: 0.1,[0.01-0.99];P=0.049). To mitigate junctional failure, our study demonstrated the utility of individualizing surgical approaches to emphasize an optimal basal construct. Achievement of tailored goals at the cranial end of the surgical construct may be equally important, especially for higher risk patients with longer fusions. III.
Sections du résumé
SUMMARY OF BACKGROUND DATA
BACKGROUND
Differing presentations of adult spinal deformity(ASD) may influence the extent of surgical intervention and use of prophylaxis at the base or the summit of a fusion construct to influence junctional failure rates.
OBJECTIVE
OBJECTIVE
Evaluate the surgical technique that has greatest influence on the rate of junctional failure following ASD surgery.
STUDY DESIGN/SETTING
METHODS
Retrospective.
METHODS
METHODS
ASD patients with two-year(2Y) data and at least 5-level fusion to pelvis were included. Patients were divided based on UIV: [Longer Construct:T1-T4; Shorter Construct:T8-T12]. Parameters assessed included matching in age-adjusted PI-LL or PT, aligning in GAP-Relative Pelvic Version or Lordosis Distribution Index. After assessing all lumbopelvic radiographic parameters, the combination of realigning the two parameters with the greatest minimizing effect of PJF constituted a Good Base. Good Summit defined as having: (1)prophylaxis at UIV(tethers,hooks,cement), (2)no lordotic change(under-contouring) greater than 10° of the UIV, (3)preoperative UIV inclination angle<30°. Multivariable regression analysis assessed effects of junction characteristics and radiographic correction individually and collectively on development of PJK and PJF in differing construct lengths, adjusting for confounders.
RESULTS
RESULTS
261 patients were included. The cohort had lower odds of PJK(OR: 0.5,[0.2-0.9];P=0.044) and PJF was less likely (OR: 0.1,[0.0-0.7];P=0.014) in the presence of a Good Summit. Normalizing pelvic compensation had the greatest radiographic effect on preventing PJF overall (OR: 0.6,[0.3-1.0];P=0.044). In Shorter Constructs, realignment had greater effect on decreasing the odds of PJF(OR: 0.2,[0.02-0.9];P=0.036). With Longer Constructs, a Good Summit lowered likelihood of PJK(OR: 0.3,[0.1-0.9];P=0.027). Good Base led to zero occurrences of PJF. In patients with severe frailty/osteoporosis, a Good Summit lowered incidence of PJK(OR: 0.4,[0.2-0.9]; P=0.041) and PJF (OR: 0.1,[0.01-0.99];P=0.049).
CONCLUSION
CONCLUSIONS
To mitigate junctional failure, our study demonstrated the utility of individualizing surgical approaches to emphasize an optimal basal construct. Achievement of tailored goals at the cranial end of the surgical construct may be equally important, especially for higher risk patients with longer fusions.
LEVEL OF EVIDENCE
METHODS
III.
Identifiants
pubmed: 37235802
doi: 10.1097/BRS.0000000000004732
pii: 00007632-990000000-00370
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest related to current work: none