Incidental Hyperferritinemia in Very Young Infants with Mild Symptoms of COVID-19 Disease.
Japan
early infantile COVID-19
hyperferritinemia
multisystem inflammatory syndrome
Journal
Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936
Informations de publication
Date de publication:
12 May 2023
12 May 2023
Historique:
received:
27
03
2023
revised:
29
04
2023
accepted:
10
05
2023
medline:
27
5
2023
pubmed:
27
5
2023
entrez:
27
5
2023
Statut:
epublish
Résumé
The number of children infected with novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has increased during the outbreak of the Omicron strain. Hyperferritinemia has been reported in severe cases of COVID-19, and in children or neonates with multisystem inflammatory syndrome (MIS). Hyperferritinemia is considered to be one of the signs of MIS, but thus far, there have been few summarized reports on it. We retrospectively analyzed four infants less than 3 months of age with SARS-CoV-2 infections treated in our institution during the outbreak of the Omicron strain. most patients were in good condition, but hyperferritinemia was observed in all of four cases. Hyperferritinemia can be observed in infantile COVID-19 patients even with mild symptoms. It is necessary to carefully monitor their clinical course and monitor the patients.
Sections du résumé
BACKGROUND
BACKGROUND
The number of children infected with novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has increased during the outbreak of the Omicron strain. Hyperferritinemia has been reported in severe cases of COVID-19, and in children or neonates with multisystem inflammatory syndrome (MIS). Hyperferritinemia is considered to be one of the signs of MIS, but thus far, there have been few summarized reports on it. We retrospectively analyzed four infants less than 3 months of age with SARS-CoV-2 infections treated in our institution during the outbreak of the Omicron strain.
RESULTS
RESULTS
most patients were in good condition, but hyperferritinemia was observed in all of four cases.
CONCLUSIONS
CONCLUSIONS
Hyperferritinemia can be observed in infantile COVID-19 patients even with mild symptoms. It is necessary to carefully monitor their clinical course and monitor the patients.
Identifiants
pubmed: 37238422
pii: children10050874
doi: 10.3390/children10050874
pmc: PMC10217696
pii:
doi:
Types de publication
Case Reports
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
Références
N Engl J Med. 2020 Jul 23;383(4):334-346
pubmed: 32598831
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
Nature. 2022 Jun;606(7914):576-584
pubmed: 35385861
Case Rep Pediatr. 2022 Mar 15;2022:2969561
pubmed: 35340538
Hepatology. 2009 Mar;49(3):887-900
pubmed: 19241483
Sci Rep. 2022 May 11;12(1):7765
pubmed: 35546159
Pediatr Rheumatol Online J. 2021 Mar 16;19(1):29
pubmed: 33726806
Eur J Pediatr. 2023 May;182(5):2089-2094
pubmed: 36912961
Lancet Child Adolesc Health. 2020 Oct;4(10):721-727
pubmed: 32711687
Pediatr Allergy Immunol. 2021 Feb;32(2):358-362
pubmed: 32931058
Front Pediatr. 2020 Sep 15;8:568
pubmed: 33042914
J Pediatric Infect Dis Soc. 2021 Dec 31;10(12):1097-1100
pubmed: 34487185
PLoS One. 2021 Jun 29;16(6):e0253894
pubmed: 34185801
Lancet Reg Health Eur. 2022 Aug;19:100443
pubmed: 35945929
BMC Med. 2013 Aug 22;11:185
pubmed: 23968282
JAMA Netw Open. 2021 Jun 1;4(6):e2111182
pubmed: 34097050
J Exp Biol. 2004 Mar;207(Pt 8):1353-60
pubmed: 15010486
JAMA Netw Open. 2021 Jun 1;4(6):e2112596
pubmed: 34115127
Arthritis Rheumatol. 2021 Apr;73(4):e13-e29
pubmed: 33277976
J Clin Virol. 2021 Feb;135:104715
pubmed: 33348220
Children (Basel). 2021 Jul 02;8(7):
pubmed: 34356552
J Clin Med. 2021 Oct 30;10(21):
pubmed: 34768620