Endotrophin Levels Are Associated with Allograft Outcomes in Kidney Transplant Recipients.


Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
05 05 2023
Historique:
received: 13 04 2023
revised: 29 04 2023
accepted: 30 04 2023
medline: 29 5 2023
pubmed: 27 5 2023
entrez: 27 5 2023
Statut: epublish

Résumé

Early prediction of kidney graft function may assist clinical management, and for this, reliable non-invasive biomarkers are needed. We evaluated endotrophin (ETP), a novel non-invasive biomarker of collagen type VI formation, as a prognostic marker in kidney transplant recipients. ETP levels were measured with the PRO-C6 ELISA in the plasma (P-ETP) of 218 and urine (U-ETP/Cr) of 172 kidney transplant recipients, one (D1) and five (D5) days, as well as three (M3) and twelve (M12) months, after transplantation. P-ETP and U-ETP/Cr at D1 (P-ETP AUC = 0.86,

Identifiants

pubmed: 37238662
pii: biom13050792
doi: 10.3390/biom13050792
pmc: PMC10216383
pii:
doi:

Substances chimiques

endotrophin 0
Collagen Type VI 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Références

BMJ Open. 2015 Aug 20;5(8):e007941
pubmed: 26297360
Am J Kidney Dis. 2012 Jun;59(6):865-73
pubmed: 22497792
Diabetes Care. 2018 Jul;41(7):1493-1500
pubmed: 29643059
Scand J Clin Lab Invest. 2016 Jul;76(4):319-23
pubmed: 27171580
Sci Rep. 2017 Dec 11;7(1):17328
pubmed: 29229941
PLoS One. 2019 Feb 28;14(2):e0212676
pubmed: 30817778
Nephrol Dial Transplant. 2023 Mar 31;38(4):1041-1052
pubmed: 36535643
Int J Organ Transplant Med. 2017;8(1):17-27
pubmed: 28299024
Nephrol Dial Transplant. 2017 Sep 01;32(9):1566-1578
pubmed: 28025385
Nephrol Dial Transplant. 2008 Sep;23(9):2995-3003
pubmed: 18408075
PLoS One. 2015 Dec 07;10(12):e0144525
pubmed: 26641456
PLoS One. 2019 Dec 30;14(12):e0226882
pubmed: 31887168
Am J Transplant. 2005 Aug;5(8):1922-5
pubmed: 15996240
Am J Transplant. 2015 Apr;15(4):863-86
pubmed: 25691290
J Pathol. 2019 Jan;247(1):99-109
pubmed: 30246318
Sci Rep. 2022 Mar 8;12(1):4079
pubmed: 35260630
Transplantation. 2008 Jan 15;85(1):1-6
pubmed: 18192903
Am J Transplant. 2010 May;10(5):1163-6
pubmed: 20420629
Am J Transplant. 2017 Jan;17(1):265-271
pubmed: 27341702
PLoS One. 2015 Feb 17;10(2):e0117315
pubmed: 25689147
Front Immunol. 2021 May 20;12:661643
pubmed: 34093552
Diabetologia. 2017 Jan;60(1):24-29
pubmed: 27717959
Transplantation. 2012 Nov 15;94(9):911-8
pubmed: 23052636
Ann Intern Med. 2006 Aug 15;145(4):247-54
pubmed: 16908915
JCI Insight. 2019 Mar 21;5:
pubmed: 30896449
PLoS One. 2017 Apr 12;12(4):e0175200
pubmed: 28403201
Nephrol Dial Transplant. 2022 May 25;37(6):1099-1108
pubmed: 33914059
Am J Transplant. 2017 Apr;17(4):1042-1049
pubmed: 27696662
Acta Diabetol. 2019 Jun;56(6):711-712
pubmed: 30852680
Kidney Int Rep. 2017 May 18;2(5):881-892
pubmed: 29270495
Nat Commun. 2014 Mar 19;5:3485
pubmed: 24647224

Auteurs

Nadja Sparding (N)

Nordic Bioscience, 2730 Herlev, Denmark.
Biomedical Sciences, Faculty of Health and Medical Science, University of Copenhagen, 2200 Copenhagen, Denmark.

Federica Genovese (F)

Nordic Bioscience, 2730 Herlev, Denmark.

Morten A Karsdal (MA)

Nordic Bioscience, 2730 Herlev, Denmark.

Nicoline V Krogstrup (NV)

Department of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.

Marie Bodilsen Nielsen (MB)

Department of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.
Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.

Mads Hornum (M)

Department of Nephrology, Rigshospitalet and Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.

Subagini Nagarajah (S)

Department of Nephrology, Odense University Hospital, 5000 Odense, Denmark.
Institute of Molecular Medicine, Cardiovascular and Renal Research, University of Southern Denmark, 5000 Odense, Denmark.

Henrik Birn (H)

Department of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.
Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.

Bente Jespersen (B)

Department of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.

Martin Tepel (M)

Department of Nephrology, Odense University Hospital, 5000 Odense, Denmark.
Institute of Molecular Medicine, Cardiovascular and Renal Research, University of Southern Denmark, 5000 Odense, Denmark.

Rikke Nørregaard (R)

Department of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH