Detection of Early Endothelial Dysfunction by Optoacoustic Tomography.
RGD-mimetics
altered shear stress
atherosclerosis
endothelial dysfunction
integrins
optoacoustic tomography
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
11 May 2023
11 May 2023
Historique:
received:
25
04
2023
revised:
08
05
2023
accepted:
09
05
2023
medline:
29
5
2023
pubmed:
27
5
2023
entrez:
27
5
2023
Statut:
epublish
Résumé
Variations in vascular wall shear stress are often presumed to result in the formation of atherosclerotic lesions at specific arterial regions, where continuous laminar flow is disturbed. The influences of altered blood flow dynamics and oscillations on the integrity of endothelial cells and the endothelial layer have been extensively studied in vitro and in vivo. Under pathological conditions, the Arg-Gly-Asp (RGD) motif binding integrin α
Identifiants
pubmed: 37239972
pii: ijms24108627
doi: 10.3390/ijms24108627
pmc: PMC10218068
pii:
doi:
Substances chimiques
Oligopeptides
0
Integrins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : SF656A04
Organisme : Medical Faculty University of Muenster
ID : MedK
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