Cannabinoid and Opioid Receptor Affinity and Modulation of Cancer-Related Signaling Pathways of Machaeriols and Machaeridiols from

Humans Cannabinoids / pharmacology Receptors, Opioid Fabaceae / chemistry NF-kappa B / metabolism Transcription Factor AP-1 / metabolism Hedgehog Proteins Signal Transduction Neoplasms / drug therapy Receptor, Cannabinoid, CB2 Receptor, Cannabinoid, CB1
CB1 CB2 Machaerium Pers. anticancer cancer signaling pathways cytotoxicity hexahydrodibenzopyran machaeridiol A–C machaeriol A–D opioid phytocannabinoid transcription factors

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
18 May 2023
Historique:
received: 14 04 2023
revised: 10 05 2023
accepted: 15 05 2023
medline: 29 5 2023
pubmed: 27 5 2023
entrez: 27 5 2023
Statut: epublish

Résumé

Machaeriols and machaeridiols are unique hexahydrodibenzopyran-type aralkyl phytocannabinoids isolated from

Identifiants

DOI: 10.3390/molecules28104162 PMID: 37241903 PMC: PMC10361207
pubmed: 37241903
pii: molecules28104162
doi: 10.3390/molecules28104162
pmc: PMC10361207
pii:
doi:

Substances chimiques

Cannabinoids 0
Receptors, Opioid 0
NF-kappa B 0
Transcription Factor AP-1 0
Hedgehog Proteins 0
Receptor, Cannabinoid, CB2 0
Receptor, Cannabinoid, CB1 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIGMS NIH HHS
ID : P20 GM104932
Pays : United States

Références

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Auteurs

Ilias Muhammad (I)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

Mohammad A Ibrahim (MA)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
ORCID: 0000-0003-0257-860X

Mallika Kumarihamy (M)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
ORCID: 0000-0001-9914-1732

Janet A Lambert (JA)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

Jin Zhang (J)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
ORCID: 0000-0001-9309-8657

Marwa H Mohammad (MH)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

Shabana I Khan (SI)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
Department of BioMolecular Sciences, Division of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

David S Pasco (DS)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
Department of BioMolecular Sciences, Division of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

Premalatha Balachandran (P)

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
ORCID: 0000-0001-7742-9591

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Cannabinoïdes › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur aux neuropeptides › Récepteurs aux opioïdes › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Fabaceae › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteur de transcription NF-kappa B › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique et à glissière à leucines › Facteur de transcription AP-1 › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines Hedgehog › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Tumeurs › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteurs de cannabinoïdes › Récepteur cannabinoïde de type CB2 › Cannabinoid and Opioid Receptor Affinity and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteurs de cannabinoïdes › Récepteur cannabinoïde de type CB1 › Cannabinoid and Opioid Receptor Affinity and...