(1→3)-α-d-Glucooligosaccharides Increase the Killing Capacity of NK Cells against Selected Human Colon Cancer Cells.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
20 May 2023
Historique:
received: 20 04 2023
revised: 17 05 2023
accepted: 18 05 2023
medline: 29 5 2023
pubmed: 27 5 2023
entrez: 27 5 2023
Statut: epublish

Résumé

Despite the progress of medicine, colorectal cancer has occupied one of the highest positions in the rankings of cancer morbidity and mortality for many years. Thus, alternative methods of its treatment are sought. One of the newer therapeutic strategies is immunotherapy based on NK cells (natural killers), which are the body's first line of defense against cancer. The aim of the study was to verify the possibility of using (1→3)-α-d-glucooligosaccharides (GOSs) obtained via acid hydrolysis of (1→3)-α-d-glucan from the fruiting body of

Identifiants

pubmed: 37241952
pii: molecules28104212
doi: 10.3390/molecules28104212
pmc: PMC10220765
pii:
doi:

Substances chimiques

Antineoplastic Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Marta Kinga Lemieszek (MK)

Department of Medical Biology, Institute of Rural Health, ul. Jaczewskiego 2, 20-090 Lublin, Poland.

Paulina Adamczyk (P)

Department of Industrial and Environmental Microbiology, Institute of Biological Science, Maria Curie-Skłodowska University, ul. Akademicka 19, 20-033 Lublin, Poland.

Iwona Komaniecka (I)

Department of Genetics and Microbiology, Institute of Biological Science, Maria Curie-Skłodowska University, ul. Akademicka 19, 20-033 Lublin, Poland.

Wojciech Rzeski (W)

Department of Medical Biology, Institute of Rural Health, ul. Jaczewskiego 2, 20-090 Lublin, Poland.
Department of Functional Anatomy and Cytobiology, Institute of Biological Science, Maria Curie-Skłodowska University, ul. Akademicka 19, 20-033 Lublin, Poland.

Michał Tomczyk (M)

Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, ul. Mickiewicza 2a, 15-230 Białystok, Poland.

Adrian Wiater (A)

Department of Industrial and Environmental Microbiology, Institute of Biological Science, Maria Curie-Skłodowska University, ul. Akademicka 19, 20-033 Lublin, Poland.

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