Desensitization Protocols for Anti-SARS-CoV-2 Vaccines in Patients with High Risk of Allergic Reactions.
COVID-19
SARS-CoV-2
allergy
desensitization
vaccine
Journal
Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355
Informations de publication
Date de publication:
27 Apr 2023
27 Apr 2023
Historique:
received:
30
03
2023
revised:
20
04
2023
accepted:
26
04
2023
medline:
27
5
2023
pubmed:
27
5
2023
entrez:
27
5
2023
Statut:
epublish
Résumé
Vaccines for SAR-CoV-2 are the most effective preventive treatment able to reduce the risk of contracting the infection and experiencing worse outcomes whenever the infection is contracted. Despite their rarity, hypersensitivity reactions to the anti-SARS-CoV-2 vaccine have been described and could become the reason not to complete the vaccination. Desensitization protocols for other vaccines have been described and validated, while the use of this approach for anti-SARS-CoV-2 vaccines is still anecdotal. We herein describe our experience with 30 patients with previous allergic reactions to anti-SARS-CoV-2 vaccines or to any of their excipients, proving that they are effective and safe; only two patients experienced hypersensitivity reaction symptoms during the desensitization procedure. Moreover, in this article, we propose desensitization protocols for the most common anti-SARS-CoV-2 vaccines.
Identifiants
pubmed: 37243013
pii: vaccines11050910
doi: 10.3390/vaccines11050910
pmc: PMC10222245
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1533-1540.e8
pubmed: 30557713
J Investig Allergol Clin Immunol. 2023 Apr 18;33(2):151-153
pubmed: 35638393
Rev Fr Allergol (2009). 2022 May;62(4):431-434
pubmed: 34484471
BMJ Case Rep. 2012 May 08;2012:
pubmed: 22605841
Ann Allergy Asthma Immunol. 2021 Apr;126(4):319-320
pubmed: 33493641
JAMA Intern Med. 2022 Apr 01;182(4):376-385
pubmed: 35188528
Drug Saf. 2021 Dec;44(12):1247-1269
pubmed: 34739716
Allergy. 2022 Aug;77(8):2292-2312
pubmed: 35112371
Front Allergy. 2022 Feb 02;3:825164
pubmed: 35386647
J Investig Allergol Clin Immunol. 2022 Oct 11;32(5):414-415
pubmed: 34924354
Open Forum Infect Dis. 2021 Oct 06;8(12):ofab507
pubmed: 34873577
J Allergy Clin Immunol. 2010 Mar;125(3):569-74, 574.e1-574.e7
pubmed: 20144472
Allergy. 2021 Jun;76(6):1629-1639
pubmed: 33452689
World Allergy Organ J. 2021 May;14(5):100541
pubmed: 33850601
JAMA. 2021 Mar 2;325(9):898
pubmed: 33533893
Eur Ann Allergy Clin Immunol. 2022 Sep;54(5):240-241
pubmed: 34753281
Allergy. 2010 Nov;65(11):1357-66
pubmed: 20716314
Clin Transl Allergy. 2022 May 17;12(5):e12152
pubmed: 35601631
Vaccines (Basel). 2023 Jan 23;11(2):
pubmed: 36851130
J Allergy Clin Immunol Glob. 2022 Aug;1(3):175-177
pubmed: 36164368
Allergy. 2023 Jan;78(1):71-83
pubmed: 36321821
Euro Surveill. 2021 Nov;26(47):
pubmed: 34823637
J Investig Allergol Clin Immunol. 2015;25(5):368-9
pubmed: 26727768
J Allergy Clin Immunol. 2012 Jul;130(1):25-43
pubmed: 22608573
Vaccine. 2007 Aug 1;25(31):5675-84
pubmed: 17448577
J Korean Med Sci. 2022 Aug 15;37(32):e251
pubmed: 35971765
JAMA. 2021 Mar 16;325(11):1101-1102
pubmed: 33576785