Outcomes of microPulse transscleral laser therapy in eyes with prior glaucoma aqueous tube shunt.


Journal

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
ISSN: 1435-702X
Titre abrégé: Graefes Arch Clin Exp Ophthalmol
Pays: Germany
ID NLM: 8205248

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 21 04 2022
accepted: 18 05 2023
revised: 04 05 2023
medline: 2 10 2023
pubmed: 29 5 2023
entrez: 29 5 2023
Statut: ppublish

Résumé

To evaluate the outcomes of micropulse transscleral laser therapy (MP-TLT) in patients with uncontrolled glaucoma and prior glaucoma aqueous tube shunt. In this single‑center, retrospective, interventional case series, eyes that underwent MP-TLT and had prior glaucoma aqueous tube shunt surgeries were included. The Cyclo Glaucoma Laser System (IRIDEX Corporation, Mountain View, CA, USA) with the MicroPulse P3 probe (version 1) was used. Post‑operative data were collected at day 1, week 1, and months 1, 3, 6, 12, 18, 24, 30 and 36. A total of 84 eyes (84 patients) with mean age of 65.8 ± 15.2 years and with advanced glaucoma (baseline mean deviation -16.25 ± 6.80 dB and best-corrected visual acuity 0.82 ± 0.83 logMar) were included in the study. Baseline mean IOP was 19.95 ± 5.6 mm Hg with a mean number of medications 3.39 ± 1.02. There were statistically significant differences in IOP between baseline and all follow-up visits (p < 0.01 for all). The mean percentage of IOP reduction between baseline and different follow-up visits ranged from 23.4% to 35.5% (p < 0.01). There was a significant reduction of visual acuity (≥ 2-lines) at 1 year (30.3%) and 2 years (76.78%). There was a statistically significant reduction in the number of glaucoma medications between baseline and all follow-up visits after postoperative week 1 (p < 0.05 for all). No severe complications including persistent hypotony and related complications were observed. At the last follow-up visit, only 24 (28%) eyes out of 84 eyes remained in the study. MP-TLT is an effective treatment for reducing IOP and decreasing the number of medications in patients with advanced glaucoma and prior glaucoma aqueous tube shunt.

Identifiants

pubmed: 37247002
doi: 10.1007/s00417-023-06119-9
pii: 10.1007/s00417-023-06119-9
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2935-2944

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Nariman Nassiri (N)

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA.

Victoria L Tseng (VL)

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA.

Chaesik Kim (C)

Kresge Eye Institute, Department of Ophthalmology, School of Medicine, Wayne State University, Detroit, MI, USA.

Peter Dentone (P)

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA.

Nathan M Francis (NM)

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA.

Alexander L Chopra (AL)

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA.

Alex Huang (A)

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA.

Brian A Francis (BA)

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA. bfrancis@mednet.ucla.edu.

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