Pregnane steroids and steroid glycosides with multidrug resistance reversal activity from Marsdenia tenacissima.

Marsdenia / chemistry Molecular Structure Steroids / pharmacology Pregnanes / pharmacology Glycosides / pharmacology Drug Resistance, Multiple
Antitumor Apocynaceae Marsdenia tenacissima Multidrug resistance Pregnane glycosides

Journal

Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 23 02 2023
revised: 17 04 2023
accepted: 24 05 2023
medline: 21 6 2023
pubmed: 30 5 2023
entrez: 29 5 2023
Statut: ppublish

Résumé

Twenty compounds comprising four pregnane steroids (2-4 & 20) and 16 pregnane glycosides (1 & 5-19) have been obtained from the ethanol extract of the roots of a Dai ethnological herb, Marsdenia tenacissima. Their structures were characterized on the basis of comprehensive spectroscopic analyses with 17 ones (1-17) being reported for the first time, including the rare cases (2 & 3) of free C

Identifiants

DOI: 10.1016/j.fitote.2023.105551 PMID: 37247696
pubmed: 37247696
pii: S0367-326X(23)00126-0
doi: 10.1016/j.fitote.2023.105551
pii:
doi:

Substances chimiques

Steroids 0
Pregnanes 0
Glycosides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

105551

Informations de copyright

Copyright © 2023. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare no conflict of interest.

Auteurs

Xiu-Qing Song (XQ)

School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China; School of Biological Science and Technology, University of Jinan, Jinan 250022, China.

Lin-Lin Tian (LL)

School of Biological Science and Technology, University of Jinan, Jinan 250022, China.

Tao Ye (T)

School of Biological Science and Technology, University of Jinan, Jinan 250022, China.

Hu Liu (H)

School of Biological Science and Technology, University of Jinan, Jinan 250022, China.

Hua Zhang (H)

School of Biological Science and Technology, University of Jinan, Jinan 250022, China. Electronic address: bio_zhangh@ujn.edu.cn.

Articles similaires

Overcoming multi-drug resistance in SCLC: a synergistic approach with venetoclax and hydroxychloroquine targeting the lncRNA LYPLAL1-DT/BCL2/BECN1 pathway.

Shuxin Li, Jianyi Lv, Zhihui Li et al.
1.00
Humans Small Cell Lung Carcinoma RNA, Long Noncoding Sulfonamides Animals

A 2000-year record of fecal biomarkers reveals past herbivore presence and impacts in a catchment in northern Yellowstone National Park, USA.

John A F Wendt, Elena Argiriadis, Cathy Whitlock et al.
1.00
Animals Feces Herbivory Biomarkers Parks, Recreational

Expanding the antiprotozoal activity and the mechanism of action of n-butyl and iso-butyl ester of quinoxaline-1,4-di-

Alonzo González-González, Oscar Sánchez-Sánchez, Lilián Yépez-Mulia et al.
1.00
Giardia lamblia Trichomonas vaginalis Entamoeba histolytica Antiprotozoal Agents Quinoxalines

Exploring the Potential of Electronic Patient-Generated Health Data for Evaluating Treatment Response to Intramuscular Steroids in Rheumatoid Arthritis: Case Series.

Mariam Al-Attar, Kesmanee Assawamartbunlue, Julie Gandrup et al.
1.00
Humans Arthritis, Rheumatoid Female Middle Aged Injections, Intramuscular

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Gentianales › Apocynaceae › Marsdenia › Pregnane steroids and steroid glycosides with...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Pregnane steroids and steroid glycosides with...
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Pregnane steroids and steroid glycosides with...
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Prégnanes › Pregnane steroids and steroid glycosides with...
questionsmedicales.fr › Glucides › Hétérosides › Pregnane steroids and steroid glycosides with...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Multirésistance aux médicaments › Pregnane steroids and steroid glycosides with...