Salvage transoral laser microsurgery for early local recurrence of glottic squamous cell cancer.
Humans
Retrospective Studies
Microsurgery
Quality of Life
Neoplasm Recurrence, Local
/ pathology
Laser Therapy
Squamous Cell Carcinoma of Head and Neck
/ surgery
Treatment Outcome
Laryngeal Neoplasms
/ pathology
Glottis
/ surgery
Head and Neck Neoplasms
/ surgery
Neoplasms, Squamous Cell
/ pathology
Lasers
Neoplasm Staging
Glottic cancer
Local recurrence
Open partial laryngectomy
Transoral laser microsurgery
Journal
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
ISSN: 1916-0216
Titre abrégé: J Otolaryngol Head Neck Surg
Pays: England
ID NLM: 101479544
Informations de publication
Date de publication:
29 May 2023
29 May 2023
Historique:
received:
17
02
2022
accepted:
23
02
2023
medline:
31
5
2023
pubmed:
30
5
2023
entrez:
29
5
2023
Statut:
epublish
Résumé
For recurrent laryngeal cancer, the feasibility of salvage transoral laser microsurgery (TLM) remains controversial. This study compared the efficacy of TLM and open partial laryngectomy (OPL) for treatment of early local recurrence of glottic squamous cell cancer (GSCC) and confirm the effectiveness of salvage TLM as a treatment option. This retrospective study involved 55 patients with early local recurrent GSCC treated with TLM, and the oncologic outcomes, functional outcomes, hospitalization time and complications were compared with a group of 40 recurrent GSCC patients matched for clinical variables of TLM group, treated by OPL by the same team of surgeons. The 5-year overall survival and disease-specific survival rates were 65.8% and 91.5%, respectively, for 55 patients with rT Salvage TLM can be used as an effective treatment option for suitable patients after a full, comprehensive, and careful assessment of the characteristics of early locally recurrent glottic carcinoma.
Sections du résumé
BACKGROUND
BACKGROUND
For recurrent laryngeal cancer, the feasibility of salvage transoral laser microsurgery (TLM) remains controversial. This study compared the efficacy of TLM and open partial laryngectomy (OPL) for treatment of early local recurrence of glottic squamous cell cancer (GSCC) and confirm the effectiveness of salvage TLM as a treatment option.
METHODS
METHODS
This retrospective study involved 55 patients with early local recurrent GSCC treated with TLM, and the oncologic outcomes, functional outcomes, hospitalization time and complications were compared with a group of 40 recurrent GSCC patients matched for clinical variables of TLM group, treated by OPL by the same team of surgeons.
RESULTS
RESULTS
The 5-year overall survival and disease-specific survival rates were 65.8% and 91.5%, respectively, for 55 patients with rT
CONCLUSION
CONCLUSIONS
Salvage TLM can be used as an effective treatment option for suitable patients after a full, comprehensive, and careful assessment of the characteristics of early locally recurrent glottic carcinoma.
Identifiants
pubmed: 37248502
doi: 10.1186/s40463-023-00628-7
pii: 10.1186/s40463-023-00628-7
pmc: PMC10228086
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
40Subventions
Organisme : Key Technologies Research and Development Program
ID : 2020YFC1316903
Organisme : Science and Technology Program of Guangzhou of China
ID : 201704020092
Organisme : 5010 Clinical Research Program of Sun Yat-sen University
ID : 2017004
Organisme : National Natural Science Foundation of China
ID : 81972528
Informations de copyright
© 2023. The Author(s).
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