Spatiotemporal dissemination of ESBL-producing Enterobacterales in municipal sewer systems: a prospective, longitudinal study in the city of Basel, Switzerland.
ESBL-producing Enterobacterales
Escherichia coli
Klebsiella pneumoniae
spatiotemporal distribution
wastewater
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2023
2023
Historique:
received:
26
02
2023
accepted:
18
04
2023
medline:
30
5
2023
pubmed:
30
5
2023
entrez:
30
5
2023
Statut:
epublish
Résumé
The contribution of community and hospital sources to the transmission of extended-spectrum β-lactamase producing Enterobacterales (ESBL-PE) remains elusive. To investigate the extent of community dissemination and the contribution of hospitals to the spread of ESBL-PE by exploring their spatiotemporal distribution in municipal wastewater of the central European city of Basel. Wastewater samples were collected monthly for two consecutive years throughout Basel, Switzerland, including 21 sites across 10 postcode areas of the city collecting either community wastewater (urban sites, Ninety-five percent (477/504) of samples were positive for ESBL-PE. Among these isolates, ESBL-PE are widely spread in municipal wastewater supporting that community sources are important reservoirs entertaining the spread of ESBL-PE. Hospital-influenced abundance of ESBL-PE appears to be species dependent.
Sections du résumé
Background
UNASSIGNED
The contribution of community and hospital sources to the transmission of extended-spectrum β-lactamase producing Enterobacterales (ESBL-PE) remains elusive.
Aim
UNASSIGNED
To investigate the extent of community dissemination and the contribution of hospitals to the spread of ESBL-PE by exploring their spatiotemporal distribution in municipal wastewater of the central European city of Basel.
Methods
UNASSIGNED
Wastewater samples were collected monthly for two consecutive years throughout Basel, Switzerland, including 21 sites across 10 postcode areas of the city collecting either community wastewater (urban sites,
Results
UNASSIGNED
Ninety-five percent (477/504) of samples were positive for ESBL-PE. Among these isolates,
Conclusion
UNASSIGNED
ESBL-PE are widely spread in municipal wastewater supporting that community sources are important reservoirs entertaining the spread of ESBL-PE. Hospital-influenced abundance of ESBL-PE appears to be species dependent.
Identifiants
pubmed: 37250050
doi: 10.3389/fmicb.2023.1174336
pmc: PMC10213686
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1174336Informations de copyright
Copyright © 2023 Gómez-Sanz, Bagutti, Roth, Alt Hug, García-Martín, Maurer Pekerman, Schindler, Furger, Eichenberger, Steffen, Egli, Hübner, Stadler, Aguilar-Bultet and Tschudin-Sutter.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Ecotoxicol Environ Saf. 2013 May;91:96-102
pubmed: 23433837
Water Res. 2019 Sep 15;161:232-241
pubmed: 31202110
Clin Infect Dis. 2017 Jul 15;65(2):342-347
pubmed: 28379311
Sci Total Environ. 2021 Sep 1;785:147269
pubmed: 33932656
Nat Commun. 2019 Mar 8;10(1):1124
pubmed: 30850636
Trends Microbiol. 2018 Mar;26(3):220-228
pubmed: 29033338
Int J Environ Res Public Health. 2020 Oct 26;17(21):
pubmed: 33114613
Appl Environ Microbiol. 2010 Jul;76(14):4772-9
pubmed: 20525867
Nat Clim Chang. 2018 Jun;8(6):510-514
pubmed: 30369964
Pathology. 2015 Apr;47(3):276-84
pubmed: 25764207
Microbiol Spectr. 2021 Sep 3;9(1):e0066121
pubmed: 34378957
J Water Health. 2021 Oct;19(5):705-723
pubmed: 34665765
N Engl J Med. 2020 Apr 2;382(14):1309-1319
pubmed: 32242356
BMC Infect Dis. 2014 Oct 01;14:528
pubmed: 25270732
PLoS One. 2020 Jan 30;15(1):e0228079
pubmed: 31999747
Environ Res. 2021 Feb;193:110487
pubmed: 33232750
Antibiotics (Basel). 2022 Jun 07;11(6):
pubmed: 35740182
Antimicrob Agents Chemother. 2008 Nov;52(11):3909-14
pubmed: 18765688
J Hosp Infect. 2016 Aug;93(4):395-402
pubmed: 26944903
Environ Res. 2022 Dec;215(Pt 2):114146
pubmed: 35988828
Syst Appl Microbiol. 2011 Feb;34(1):2-11
pubmed: 21288677
BMJ Open. 2018 Feb 17;8(2):e021823
pubmed: 29455172
Science. 2020 Feb 7;367(6478):630-632
pubmed: 32029617
Lancet. 2022 Feb 12;399(10325):629-655
pubmed: 35065702
J Hazard Mater. 2022 Apr 5;427:128155
pubmed: 34991006
Swiss Med Wkly. 2022 Jun 27;152:w30202
pubmed: 35822578
Clin Microbiol Infect. 2014 Jan;20 Suppl 1:1-55
pubmed: 24329732
J Antimicrob Chemother. 2005 Jul;56(1):52-9
pubmed: 15917288
Sci Total Environ. 2020 Nov 15;743:140804
pubmed: 32758846
Int J Antimicrob Agents. 2015 Jan;45(1):25-32
pubmed: 25465520
Diagn Microbiol Infect Dis. 2016 Mar;84(3):181-3
pubmed: 26712266
Lancet Infect Dis. 2008 Mar;8(3):159-66
pubmed: 18291338
Infect Genet Evol. 2018 Jul;61:185-188
pubmed: 29626676
Clin Infect Dis. 2014 Jun;58(12):1658-65
pubmed: 24795329
PLoS One. 2019 Nov 7;14(11):e0224861
pubmed: 31697734
Clin Infect Dis. 2012 Dec;55(11):1505-11
pubmed: 22955436
Appl Environ Microbiol. 2013 May;79(9):3021-6
pubmed: 23455339
Lancet Infect Dis. 2018 Mar;18(3):318-327
pubmed: 29276051
Clin Infect Dis. 2013 Feb;56(4):478-87
pubmed: 23243181
Environ Sci Process Impacts. 2013 Mar;15(3):617-22
pubmed: 23738360
Euro Surveill. 2022 Nov;27(45):
pubmed: 36367012
Appl Microbiol Biotechnol. 2015 Jul;99(13):5547-62
pubmed: 25776061
Front Public Health. 2021 Aug 02;9:686789
pubmed: 34409007
BMC Microbiol. 2017 May 25;17(1):128
pubmed: 28545528
Microbiol Spectr. 2021 Dec 22;9(3):e0066421
pubmed: 34756091
Folia Microbiol (Praha). 2017 May;62(3):221-227
pubmed: 28063019
Lancet Infect Dis. 2019 Jan;19(1):17-18
pubmed: 30449661
Lancet Planet Health. 2019 Aug;3(8):e357-e369
pubmed: 31439317
Environ Int. 2021 Jul;152:106466
pubmed: 33706038