Adherence to Overactive Bladder Syndrome Treatments Recent Developments and Future Perspectives.
OAB
adherence
antimuscarinics
compliance
persistence
β3 agonists
Journal
International journal of women's health
ISSN: 1179-1411
Titre abrégé: Int J Womens Health
Pays: New Zealand
ID NLM: 101531698
Informations de publication
Date de publication:
2023
2023
Historique:
received:
20
01
2023
accepted:
05
05
2023
medline:
30
5
2023
pubmed:
30
5
2023
entrez:
30
5
2023
Statut:
epublish
Résumé
Overactive bladder (OAB) is a common and distressing condition which is known to have a significant effect on Health-Related Quality of Life (HRQoL). Whilst all patients complaining of overactive bladder symptoms will, in theory, initially benefit from conservative measures, many will require pharmacological therapy. Antimuscarinics currently remain the most commonly used drugs to treat OAB although compliance and persistence can be poor due to concerns regarding adverse events and lack of efficacy. This review will explore the common management strategies for OAB with a particular focus on patient adherence to therapy including compliance and persistence. The role of antimuscarinics and the B3-agonist, mirabegron, will be considered along with barriers to their efficacy and adoption. For those patients in whom conservative and pharmacological treatment proves ineffective or is unsuitable, the management of refractory OAB will also be considered. In addition, the role of current and future developments will be examined.
Identifiants
pubmed: 37251090
doi: 10.2147/IJWH.S369588
pii: 369588
pmc: PMC10224686
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
799-811Informations de copyright
© 2023 Robinson et al.
Déclaration de conflit d'intérêts
Mr Dudley Robinson reports personal fees from Allergan, outside the submitted work; Professor Linda Cardozo is a Consultant for ConvaTech and Merck, outside the submitted work. The authors report no other conflict of interest in this work.
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