Interferon regulatory factor 7 in inflammation, cancer and infection.
IRF7
cancer
infection
inflammation
interferon
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2023
2023
Historique:
received:
21
03
2023
accepted:
26
04
2023
medline:
1
6
2023
pubmed:
30
5
2023
entrez:
30
5
2023
Statut:
epublish
Résumé
Interferon regulatory factor 7 (IRF7), a member of the interferon regulatory factors (IRFs) family, is located downstream of the pattern recognition receptors (PRRs)-mediated signaling pathway and is essential for the production of type I interferon (IFN-I). Activation of IRF7 inhibits various viral and bacterial infections and suppresses the growth and metastasis of some cancers, but it may also affect the tumor microenvironment and promote the development of other cancers. Here, we summarize recent advances in the role of IRF7 as a multifunctional transcription factor in inflammation, cancer and infection by regulating IFN-I production or IFN-I-independent signaling pathways.
Identifiants
pubmed: 37251373
doi: 10.3389/fimmu.2023.1190841
pmc: PMC10213216
doi:
Substances chimiques
Interferon Regulatory Factor-7
0
Interferon Type I
0
IRF7 protein, human
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1190841Informations de copyright
Copyright © 2023 Qing and Liu.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Virulence. 2017 Oct 3;8(7):1303-1315
pubmed: 28422568
J Cancer. 2017 Jan 13;8(2):207-219
pubmed: 28243325
Mol Cell Biol. 2002 Jun;22(11):3942-57
pubmed: 11997525
Eur J Immunol. 2020 Aug;50(8):1142-1153
pubmed: 32135578
mBio. 2018 Apr 17;9(2):
pubmed: 29666281
Life Sci. 2021 Jan 1;264:118709
pubmed: 33152351
PLoS Pathog. 2017 Apr 5;13(4):e1006305
pubmed: 28380049
PLoS One. 2010 Jul 26;5(7):e11776
pubmed: 20668674
Oncol Res. 2017 Apr 14;25(4):511-522
pubmed: 27733217
Nat Rev Immunol. 2006 Sep;6(9):644-58
pubmed: 16932750
J Virol. 2008 Sep;82(17):8465-75
pubmed: 18562536
Nat Commun. 2018 Feb 5;9(1):493
pubmed: 29402958
Am J Transl Res. 2016 Feb 15;8(2):506-15
pubmed: 27158343
J Virol. 2012 Oct;86(20):11254-65
pubmed: 22875973
Front Microbiol. 2017 Apr 20;8:697
pubmed: 28473823
Cell Prolif. 2015 Dec;48(6):643-9
pubmed: 26597380
J Biol Chem. 1998 Oct 30;273(44):29210-7
pubmed: 9786932
Glia. 2015 Apr;63(4):595-610
pubmed: 25422089
Tumour Biol. 2015 Jul;36(7):5561-9
pubmed: 25680411
Nature. 2005 Apr 7;434(7034):767-72
pubmed: 15815631
Cell Biol Int. 2021 Apr;45(4):831-838
pubmed: 33325089
J Allergy Clin Immunol. 2018 Jun;141(6):2085-2093.e1
pubmed: 29371118
Fish Shellfish Immunol. 2011 Jan;30(1):67-76
pubmed: 20883793
J Immunol. 2015 May 15;194(10):4924-30
pubmed: 25847975
J Cell Biochem. 2020 Nov;121(11):4377-4385
pubmed: 31904147
Am J Pathol. 2016 May;186(5):1234-44
pubmed: 27105736
J Allergy Clin Immunol. 2016 Jan;137(1):75-86.e8
pubmed: 26194544
J Virol. 2020 Nov 23;94(24):
pubmed: 32967960
J Virol. 2019 Feb 5;93(4):
pubmed: 30518647
PLoS One. 2022 Oct 21;17(10):e0276460
pubmed: 36269754
Mol Cell Biol. 1997 Oct;17(10):5748-57
pubmed: 9315633
Cell Signal. 2010 Jun;22(6):883-7
pubmed: 20043992
PLoS One. 2015 Jun 29;10(6):e0131919
pubmed: 26121689
Ann Rheum Dis. 2019 Nov;78(11):1583-1591
pubmed: 31439591
Nat Commun. 2018 Oct 12;9(1):4246
pubmed: 30315268
J Virol. 2019 Nov 26;93(24):
pubmed: 31578290
Virology. 2013 May 10;439(2):152-62
pubmed: 23490048
Cell Physiol Biochem. 2018;50(1):179-195
pubmed: 30278439
Cold Spring Harb Symp Quant Biol. 2013;78:105-16
pubmed: 24092468
Oncogene. 2017 May 25;36(21):2969-2980
pubmed: 28092673
J Exp Med. 2022 Jul 4;219(7):
pubmed: 35670811
J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D22-33
pubmed: 24355638
Immunity. 2010 Dec 14;33(6):863-77
pubmed: 21167755
Front Cell Dev Biol. 2022 Feb 17;10:789073
pubmed: 35252169
BMC Med Genomics. 2015 Aug 18;8:52
pubmed: 26282854
J Transl Med. 2019 Dec 13;17(1):419
pubmed: 31836022
Immunity. 2006 Sep;25(3):349-60
pubmed: 16979567
Virus Res. 2022 Dec;322:198931
pubmed: 36130654
Virology. 2018 May;518:1-7
pubmed: 29427864
J Exp Med. 2018 Nov 5;215(11):2919-2935
pubmed: 30337468
Cell Rep. 2019 Nov 26;29(9):2718-2730.e6
pubmed: 31775040
Nat Rev Immunol. 2009 Oct;9(10):692-703
pubmed: 19859064
Virulence. 2017 Aug 18;8(6):848-858
pubmed: 27763806
Annu Rev Immunol. 2008;26:535-84
pubmed: 18303999
Eur J Immunol. 2015 Jan;45(1):130-41
pubmed: 25319247
Can J Cardiol. 2015 Apr;31(4):489-501
pubmed: 25840098
Rheumatology (Oxford). 2012 Jun;51(6):1017-26
pubmed: 21900368
J Interferon Cytokine Res. 2002 Jan;22(1):95-101
pubmed: 11846980
Front Immunol. 2022 Apr 07;13:863957
pubmed: 35464447
EMBO J. 2014 Dec 17;33(24):2906-21
pubmed: 25385836