The menstrual cycle regularity and skin: irregular menstrual cycle affects skin physiological properties and skin bacterial microbiome in urban Chinese women.
Hormones
Menstrual cycle
Skin barrier
Skin microbiota
Skin physiological parameters
TEWL
Journal
BMC women's health
ISSN: 1472-6874
Titre abrégé: BMC Womens Health
Pays: England
ID NLM: 101088690
Informations de publication
Date de publication:
31 05 2023
31 05 2023
Historique:
received:
18
01
2023
accepted:
25
04
2023
medline:
2
6
2023
pubmed:
1
6
2023
entrez:
31
5
2023
Statut:
epublish
Résumé
The regularity of the menstrual cycle directly affects women's health. Many studies have focused on menstrual health; however, menstrual cycle regularity-related variations in skin physiological characteristics and skin microbiota have been seldom investigated. To investigate the menstrual cycle regularity-related variations in skin physiological characteristics and skin microbiota of 197 cases of Chinese women aged 18-35 years living in shanghai in 2021. Based on a self-evaluation questionnaire, the volunteers were divided into three groups C1 (those with a regular menstrual cycle), C2 (those with a less regular menstrual cycle) and C3 (those with an irregular menstrual cycle). The physiological parameters of facial skin were measured by non-invasive methods and the skin microbiome was analyzed by 16S rRNA high-throughput sequencing. In the C3 group, the hydration content was significantly decreased (p < 0.05), the TEWL was significantly increased (p < 0.05), and the sebum content was increased (p > 0.05), indicating that the skin barrier integrity weakened with increased menstrual cycle irregularity. Additionally, the melanin level, L value and b value were significantly decreased (p < 0.05) in the C3 group, but the a value was significantly increased (p < 0.001), which indicated that the skin color became darker. Furthermore, the skin microbiota diversity decreased with increasing cycle irregularity, but the differences were not significant. The skin microbiota composition showed that the proportion of Firmicutes, Acinetobacter, Staphylococcus and Cutibacterium were increased in those with an irregular menstrual cycle, indicating that alterations in the ratio of bacterial phyla and/or genera might disturb skin homeostasis. Spearman correlation analysis revealed strong correlations between the microbiota and skin physiological parameters. Based on the associations among hormones, skin physiological parameters and skin microbiota, it is possible that the skin physiological parameters, as well as the skin microbial diversity and composition, change with hormonal fluctuations during the menstrual cycle. An irregular menstrual cycle can affect skin physiological characteristics and the skin microbiota. Female with an irregular menstrual cycle should strengthen skin care practices and use skin care products with moisturising and soothing effects to protect their skin.
Sections du résumé
BACKGROUND
The regularity of the menstrual cycle directly affects women's health. Many studies have focused on menstrual health; however, menstrual cycle regularity-related variations in skin physiological characteristics and skin microbiota have been seldom investigated.
METHODS
To investigate the menstrual cycle regularity-related variations in skin physiological characteristics and skin microbiota of 197 cases of Chinese women aged 18-35 years living in shanghai in 2021. Based on a self-evaluation questionnaire, the volunteers were divided into three groups C1 (those with a regular menstrual cycle), C2 (those with a less regular menstrual cycle) and C3 (those with an irregular menstrual cycle). The physiological parameters of facial skin were measured by non-invasive methods and the skin microbiome was analyzed by 16S rRNA high-throughput sequencing.
RESULTS
In the C3 group, the hydration content was significantly decreased (p < 0.05), the TEWL was significantly increased (p < 0.05), and the sebum content was increased (p > 0.05), indicating that the skin barrier integrity weakened with increased menstrual cycle irregularity. Additionally, the melanin level, L value and b value were significantly decreased (p < 0.05) in the C3 group, but the a value was significantly increased (p < 0.001), which indicated that the skin color became darker. Furthermore, the skin microbiota diversity decreased with increasing cycle irregularity, but the differences were not significant. The skin microbiota composition showed that the proportion of Firmicutes, Acinetobacter, Staphylococcus and Cutibacterium were increased in those with an irregular menstrual cycle, indicating that alterations in the ratio of bacterial phyla and/or genera might disturb skin homeostasis. Spearman correlation analysis revealed strong correlations between the microbiota and skin physiological parameters. Based on the associations among hormones, skin physiological parameters and skin microbiota, it is possible that the skin physiological parameters, as well as the skin microbial diversity and composition, change with hormonal fluctuations during the menstrual cycle.
CONCLUSIONS
An irregular menstrual cycle can affect skin physiological characteristics and the skin microbiota. Female with an irregular menstrual cycle should strengthen skin care practices and use skin care products with moisturising and soothing effects to protect their skin.
Identifiants
pubmed: 37259058
doi: 10.1186/s12905-023-02395-z
pii: 10.1186/s12905-023-02395-z
pmc: PMC10230734
doi:
Substances chimiques
RNA, Ribosomal, 16S
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
292Informations de copyright
© 2023. The Author(s).
Références
Obstet Gynecol Surv. 2009 Jan;64(1):58-72
pubmed: 19099613
Science. 2019 Jan 4;363(6422):
pubmed: 30523076
Comput Methods Biomech Biomed Engin. 2015;18 Suppl 1:1912-3
pubmed: 26273846
Clin Psychol Rev. 2018 Dec;66:80-96
pubmed: 29945741
J Cosmet Dermatol. 2016 Dec;15(4):549-558
pubmed: 27405934
J Cosmet Sci. 2005 Sep-Oct;56(5):311-21
pubmed: 16258697
J Nutr Metab. 2020 Nov 23;2020:5980685
pubmed: 33489364
Genome Res. 2012 May;22(5):850-9
pubmed: 22310478
Women Health. 2018 Nov-Dec;58(10):1135-1150
pubmed: 28682185
Occup Environ Med. 2004 Dec;61(12):1021-6
pubmed: 15550609
Am J Clin Dermatol. 2011 Oct 1;12(5):297-311
pubmed: 21714580
Nat Rev Microbiol. 2018 Mar;16(3):143-155
pubmed: 29332945
Int J Dermatol. 1984 Jun;23(5):322-9
pubmed: 6746182
J Cosmet Dermatol. 2021 Jan;20(1):249-255
pubmed: 32333703
J Affect Disord. 2017 Feb;209:53-58
pubmed: 27886570
Eur J Clin Microbiol Infect Dis. 2019 Sep;38(9):1677-1685
pubmed: 31152265
Nat Rev Immunol. 2016 May 27;16(6):353-66
pubmed: 27231051
Br Med J. 1961 Aug 26;2(5251):563-5
pubmed: 13773989
Semin Immunol. 2013 Nov 30;25(5):370-7
pubmed: 24268438
Paediatr Perinat Epidemiol. 2020 May;34(3):318-327
pubmed: 32104920
Infect Genet Evol. 2011 Jul;11(5):839-48
pubmed: 21463709
Microorganisms. 2020 Nov 07;8(11):
pubmed: 33171837
Arch Psychiatr Nurs. 2008 Oct;22(5):254-65
pubmed: 18809118
Cell. 2016 May 5;165(4):854-66
pubmed: 27153496
J Affect Disord. 2017 Mar 01;210:43-48
pubmed: 28012351
Exp Dermatol. 2021 Oct;30(10):1366-1374
pubmed: 32347582
Acta Obstet Gynecol Scand. 2005 Jul;84(7):645-9
pubmed: 15954873
J Adolesc Health. 2009 Mar;44(3):237-43
pubmed: 19237109
J Invest Dermatol. 1998 Jan;110(1):20-3
pubmed: 9424081
Gynecol Endocrinol. 2020 Dec;36(12):1101-1105
pubmed: 32783549
Psychoneuroendocrinology. 2017 Jan;75:44-51
pubmed: 27770662
J Invest Dermatol. 2018 Oct;138(10):2106-2107
pubmed: 30244719
Sleep Med. 2017 Jul;35:62-66
pubmed: 28619183
Behav Med. 2002 Winter;27(4):173-8
pubmed: 12165971
Clin Cosmet Investig Dermatol. 2022 Jun 07;15:1051-1063
pubmed: 35698548
Br J Dermatol. 2019 Dec;181(6):1254-1264
pubmed: 30985920
Microorganisms. 2021 Oct 25;9(11):
pubmed: 34835341
Immunity. 2017 Apr 18;46(4):562-576
pubmed: 28423337
Sci Rep. 2016 Oct 27;6:36062
pubmed: 27786295
Clin Exp Dermatol. 2015 Mar;40(2):111-5
pubmed: 25683236
Microorganisms. 2021 Mar 18;9(3):
pubmed: 33803499
Am J Obstet Gynecol. 2020 Nov;223(5):624-664
pubmed: 32707266
Obstet Gynecol Clin North Am. 2019 Sep;46(3):441-453
pubmed: 31378287
Nature. 2014 Oct 2;514(7520):59-64
pubmed: 25279917