Disulfidptosis: a new form of programmed cell death.


Journal

Journal of experimental & clinical cancer research : CR
ISSN: 1756-9966
Titre abrégé: J Exp Clin Cancer Res
Pays: England
ID NLM: 8308647

Informations de publication

Date de publication:
31 May 2023
Historique:
received: 04 04 2023
accepted: 15 05 2023
medline: 2 6 2023
pubmed: 1 6 2023
entrez: 31 5 2023
Statut: epublish

Résumé

Disulfidptosis, a new form of cell death triggered by disulfide stress, is characterized by the collapse of cytoskeleton proteins and F-actin due to the intracellular accumulation of disulfides. This discovery will eventually aid in the development of therapeutic strategies against cancer.

Identifiants

pubmed: 37259067
doi: 10.1186/s13046-023-02712-2
pii: 10.1186/s13046-023-02712-2
pmc: PMC10230712
doi:

Substances chimiques

Actins 0
Cytoskeletal Proteins 0

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

137

Subventions

Organisme : Science Foundation of the Fujian Province
ID : 2020J011287

Informations de copyright

© 2023. The Author(s).

Références

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pubmed: 19538140
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pubmed: 10863552
Antioxid Redox Signal. 2013 May 1;18(13):1623-41
pubmed: 23075118
J Cell Sci. 2017 Jul 15;130(14):2235-2241
pubmed: 28646090
Br J Cancer. 2021 Mar;124(5):862-879
pubmed: 33223534
PLoS Pathog. 2022 Sep 19;18(9):e1010864
pubmed: 36121870
Nat Cell Biol. 2023 Mar;25(3):375-376
pubmed: 36918690
Curr Opin Cell Biol. 2009 Dec;21(6):885-93
pubmed: 19850457
Nat Cell Biol. 2023 Mar;25(3):404-414
pubmed: 36747082
Nat Cell Biol. 2020 Apr;22(4):476-486
pubmed: 32231310
Science. 2022 Mar 18;375(6586):1254-1261
pubmed: 35298263
Protein Cell. 2021 Aug;12(8):599-620
pubmed: 33000412

Auteurs

Tingjin Zheng (T)

Department of Clinical Laboratory, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou City, 362000, Fujian, China. zhengtingjin@hotmail.com.

Qingbo Liu (Q)

Department of Hepatobiliary Surgery, Shunde Hospital of Southern Medical University (The First People's Hospital of Shunde), Foshan, 528300, Guangdong, China.

Feiyue Xing (F)

Institute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou, Guangdong, China.

Chong Zeng (C)

Medical Research Center, Shunde Hospital, Southern Medical University, Foshan, 528300, Guangdong, China. wonder10@126.com.

Weidong Wang (W)

Department of Hepatobiliary Surgery, Shunde Hospital of Southern Medical University (The First People's Hospital of Shunde), Foshan, 528300, Guangdong, China. wangweidong1968@126.com.

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Classifications MeSH