Use of laboratory animals and issues regarding the procurement of animals for research in Korea.
Animal ethics
Animal experiment
Animal procurement
Animal welfare
Laboratory animals
Journal
Laboratory animal research
ISSN: 1738-6055
Titre abrégé: Lab Anim Res
Pays: England
ID NLM: 101560684
Informations de publication
Date de publication:
01 Jun 2023
01 Jun 2023
Historique:
received:
19
01
2023
accepted:
13
05
2023
revised:
25
04
2023
medline:
1
6
2023
pubmed:
1
6
2023
entrez:
31
5
2023
Statut:
epublish
Résumé
Laboratory animals remain critical to biomedical research, despite the increasing availability of alternative approaches. Indeed, scientists strive to reduce and refine and replace the use of laboratory animals, even in the face of public calls for ever-more stringent regulation for the protection and care of animals in research. This report outlines the current status and legal regulatory issues with regard to the procurement and use of animals for research in Korea. The number of animals used for education and research purposes was increased nationwide, from 2.5 to 4.9 million in 2015 and 2021, respectively. When compared with figures from the UK, institutions in Korea were found to use more mammals such as mice and dogs. In our research, we identified three major issues concerning recent animal supply in Korea, particularly: (1) Purchase of dogs from unregistered animal supplier for a dog cloning project; (2) Purchase of dogs from an unclear source for veterinary education and training; (3) Illegal cat experiments using cats obtained from unauthorized routes. Our findings support the notion that alternatives to laboratory animal research should be implemented. We conclude that improvements in the regulations and guidelines for animal suppliers, together with the recent introduction of legislation will improve animal safety and wellbeing of animals in laboratory research in Korea.
Sections du résumé
BACKGROUND
BACKGROUND
Laboratory animals remain critical to biomedical research, despite the increasing availability of alternative approaches. Indeed, scientists strive to reduce and refine and replace the use of laboratory animals, even in the face of public calls for ever-more stringent regulation for the protection and care of animals in research. This report outlines the current status and legal regulatory issues with regard to the procurement and use of animals for research in Korea.
RESULTS
RESULTS
The number of animals used for education and research purposes was increased nationwide, from 2.5 to 4.9 million in 2015 and 2021, respectively. When compared with figures from the UK, institutions in Korea were found to use more mammals such as mice and dogs. In our research, we identified three major issues concerning recent animal supply in Korea, particularly: (1) Purchase of dogs from unregistered animal supplier for a dog cloning project; (2) Purchase of dogs from an unclear source for veterinary education and training; (3) Illegal cat experiments using cats obtained from unauthorized routes.
CONCLUSIONS
CONCLUSIONS
Our findings support the notion that alternatives to laboratory animal research should be implemented. We conclude that improvements in the regulations and guidelines for animal suppliers, together with the recent introduction of legislation will improve animal safety and wellbeing of animals in laboratory research in Korea.
Identifiants
pubmed: 37259162
doi: 10.1186/s42826-023-00161-8
pii: 10.1186/s42826-023-00161-8
pmc: PMC10232344
doi:
Types de publication
Journal Article
Langues
eng
Pagination
10Subventions
Organisme : Kwangju Women`s University
ID : KWU23-046
Informations de copyright
© 2023. The Author(s).
Références
Nature. 2005 Aug 4;436(7051):641
pubmed: 16079832
Exp Anim. 2021 Nov 10;70(4):532-540
pubmed: 34193732
ILAR J. 2016 May 1;57(3):301-311
pubmed: 29117401
Arch Toxicol. 2022 Jul;96(7):1935-1950
pubmed: 35503372
BMB Rep. 2014 Apr;47(4):179-83
pubmed: 24568878
Altern Lab Anim. 2021 Sep;49(5):182-196
pubmed: 34836474
Vet Res. 2021 Mar 10;52(1):43
pubmed: 33691792
Nature. 2019 May;569(7758):612
pubmed: 31142871
Altern Lab Anim. 2019 Nov-Dec;47(5-6):196-213
pubmed: 32090616
J Periodontal Implant Sci. 2022 Feb;52(1):1-2
pubmed: 35187869