Unusual Manifestation of Extraosseous Ewing Sarcoma: Report of 3 Cases.
cytogenetics
extraosseous Ewing sarcoma
surgical resection
Journal
Balkan journal of medical genetics : BJMG
ISSN: 1311-0160
Titre abrégé: Balkan J Med Genet
Pays: Poland
ID NLM: 9806959
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
medline:
2
6
2023
pubmed:
2
6
2023
entrez:
2
6
2023
Statut:
epublish
Résumé
Ewing sarcoma (ES), described as a diffuse endothelioma of the bone, is divided into two categories: osseous and extraosseous, which mainly affects adolescents. Extraosseous Ewing Sarcomas (EES) are rare tumors originating from soft tissues. Their clinical presentation depends mainly on the primary location of the tumor and are highly chemosensitive and radiosensitive. The purpose of this study was to describe the clinical characteristics and outcomes of 3 children with EES and uncommon presentation treated in our Unit. The diagnosis of EES was confirmed by biopsy and cytogenetic analysis with fluorescence in situ hybridization (FISH). Surgical excision was planned as primary treatment, followed by adjuvant chemotherapy according to EURO-E.W.I.N.G protocol. To date, all patients are alive, 1, 3 and 4 years after completion of treatment, with no signs of recurrence or metastasis.
Identifiants
pubmed: 37265973
doi: 10.2478/bjmg-2022-0022
pii: bjmg-2022-0022
pmc: PMC10230840
doi:
Types de publication
Journal Article
Langues
eng
Pagination
77-81Informations de copyright
© 2022 Ioannidou M. et al., published by Sciendo.
Déclaration de conflit d'intérêts
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.
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