Clinical Application of

99mTc-pyrophosphate imaging MRI echocardiography light-chain cardiac amyloidosis transthyretin cardiac amyloidosis

Journal

Journal of nuclear medicine technology
ISSN: 1535-5675
Titre abrégé: J Nucl Med Technol
Pays: United States
ID NLM: 0430303

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 16 02 2023
revised: 10 04 2023
medline: 5 6 2023
pubmed: 3 6 2023
entrez: 2 6 2023
Statut: ppublish

Résumé

Cardiac amyloidosis (CA) is an infiltrative cardiomyopathy resulting from deposition of insoluble amyloid protein in the myocardial interstitium. The accumulation of amyloid protein causes the myocardium to thicken and stiffen, leading to diastolic dysfunction and, eventually, heart failure. Two primary types of amyloidosis-transthyretin and immunoglobulin light chain-account for nearly 95% of all CA diagnoses. Three case studies are presented. The first demonstrates a patient positive for transthyretin amyloidosis, the second demonstrates a patient positive for light-chain CA, and the third demonstrates a patient showing blood-pool uptake on the [

Identifiants

pubmed: 37268320
pii: 51/2/125
doi: 10.2967/jnmt.123.265614
doi:

Substances chimiques

diphosphoric acid 4E862E7GRQ
Diphosphates 0
Amyloidogenic Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

125-128

Informations de copyright

© 2023 by the Society of Nuclear Medicine and Molecular Imaging.

Auteurs

Sami Shoura (S)

Department of Internal Medicine, Cook County Health, Chicago, Illinois.

Saurabh Malhotra (S)

Division of Cardiology, Cook County Health, Chicago, Illinois; and saurabh.malhotra@cookcountyhhs.org.
Division of Cardiology, Rush Medical College, Chicago, Illinois.

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Classifications MeSH