Characterization of sulfasalazine-bovine serum albumin and human serum albumin interaction by spectroscopic and theoretical approach.
BSA/HSA binding
Computational study
Multispectroscopic study
Site marker experiment
Journal
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
ISSN: 1873-3557
Titre abrégé: Spectrochim Acta A Mol Biomol Spectrosc
Pays: England
ID NLM: 9602533
Informations de publication
Date de publication:
05 Nov 2023
05 Nov 2023
Historique:
received:
14
02
2023
revised:
20
04
2023
accepted:
10
05
2023
medline:
19
6
2023
pubmed:
4
6
2023
entrez:
3
6
2023
Statut:
ppublish
Résumé
The interaction of sulfasalazine (SZ) with the carrier proteins bovine serum albumin (BSA) and human serum albumin (HSA) was explored by fluorescence, absorption and circular dichroism (CD) spectroscopy along within silicotechniques. The spectral alteration observed in fluorescence, absorption and CD spectra upon the addition of SZ confirmed the complex formation of SZ with BSA and HSA. The inverse temperature dependence behaviour of theK
Identifiants
pubmed: 37269654
pii: S1386-1425(23)00550-4
doi: 10.1016/j.saa.2023.122865
pii:
doi:
Substances chimiques
Serum Albumin, Bovine
27432CM55Q
Serum Albumin, Human
ZIF514RVZR
Sulfasalazine
3XC8GUZ6CB
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
122865Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.