Towards therapeutic drug monitoring of antibiotic levels - analyzing the pharmacokinetics of levofloxacin using DUV-resonance Raman spectroscopy.

Levofloxacin Spectrum Analysis, Raman / methods Drug Monitoring Anti-Bacterial Agents Least-Squares Analysis

Journal

The Analyst
ISSN: 1364-5528
Titre abrégé: Analyst
Pays: England
ID NLM: 0372652

Informations de publication

Date de publication:
26 Jun 2023
Historique:
medline: 27 6 2023
pubmed: 5 6 2023
entrez: 5 6 2023
Statut: epublish

Résumé

Therapeutic drug monitoring (TDM) plays an important role in clinical practice. Here, pharmacokinetics has a decisive influence on the effective antibiotic concentration during treatment. Moreover, different kinetics exist for different administration forms. Accordingly, adjusting the correct concentration depends, in addition to gender, age, weight, clinical picture,

Identifiants

DOI: 10.1039/d3an00402c PMID: 37272589
pubmed: 37272589
doi: 10.1039/d3an00402c
doi:

Substances chimiques

Levofloxacin 6GNT3Y5LMF
Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3057-3064

Auteurs

Christian Domes (C)

Leibniz Institute of Photonic Technology, 07745 Jena, Germany.

Juergen Popp (J)

Leibniz Institute of Photonic Technology, 07745 Jena, Germany.
Abbe Center of Photonics, Friedrich Schiller University, 07745 Jena, Germany.

Stefan Hagel (S)

Institute of Infectious Diseases and Infection Control, University Hospital, 07747 Jena, Germany.

Mathias W Pletz (MW)

Institute of Infectious Diseases and Infection Control, University Hospital, 07747 Jena, Germany.

Torsten Frosch (T)

Biophotonics and Biomedical Engineering Group, Technical University Darmstadt, Merckstraße 25, 64283 Darmstadt, Germany. torsten.frosch@tu-darmstadt.de.
Leibniz Institute of Photonic Technology, 07745 Jena, Germany.
Abbe Center of Photonics, Friedrich Schiller University, 07745 Jena, Germany.
ORCID: 0000-0003-3358-8878

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Quinolinone › Fluoroquinolones › Ofloxacine › Lévofloxacine › Towards therapeutic drug monitoring of...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Analyse spectrale Raman › Towards therapeutic drug monitoring of...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Monitorage physiologique › Surveillance des médicaments › Towards therapeutic drug monitoring of...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Towards therapeutic drug monitoring of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de régression › Méthode des moindres carrés › Towards therapeutic drug monitoring of...