Expanding endoscopic boundaries: Endoscopic resection of large appendiceal orifice polyps with endoscopic mucosal resection and endoscopic submucosal dissection.
Adenomatous polyps
Appendiceal orifice polyps
En bloc resection
Endoscopic mucosal resection
Endoscopic submucosal dissection
Polyp resection
Journal
World journal of gastrointestinal endoscopy
ISSN: 1948-5190
Titre abrégé: World J Gastrointest Endosc
Pays: United States
ID NLM: 101532474
Informations de publication
Date de publication:
16 May 2023
16 May 2023
Historique:
received:
17
02
2023
revised:
10
04
2023
accepted:
18
04
2023
medline:
5
6
2023
pubmed:
5
6
2023
entrez:
5
6
2023
Statut:
ppublish
Résumé
Large appendiceal orifice polyps are traditionally treated surgically. Recently, endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have been utilized as alternative resection techniques. To evaluate the efficacy and safety of endoscopic resection techniques for the management of large appendiceal orifice polyps. This was a retrospective observational study conducted to assess the feasibility and safety of EMR and ESD for large appendiceal orifice polyps. This project was approved by the Baylor College of Medicine Institutional Review Board. Patients who underwent endoscopic resection of appendiceal orifice polyps ≥ 1 cm from 2015 to 2022 at a tertiary referral endoscopy center in the United States were enrolled. The main outcomes of this study included A total of 19 patients were identified. Most patients were female (53%) and Caucasian (95%). The mean age was 63.3 ± 10.8 years, and the average body mass index was 28.8 ± 6.4. The mean polyp size was 25.5 ± 14.2 mm. 74% of polyps were localized to the appendix (at or inside the appendiceal orifice) and the remaining extended into the cecum. 68% of polyps occupied ≥ 50% of the appendiceal orifice circumference. The mean procedure duration was 61.6 ± 37.9 minutes. Polyps were resected Our study highlights how endoscopic mucosal resection, endoscopic submucosal dissection, and hybrid procedures are all appropriate techniques with minimal adverse effects, further validating the utility of endoscopic procedures in the management of large appendiceal polyps.
Sections du résumé
BACKGROUND
BACKGROUND
Large appendiceal orifice polyps are traditionally treated surgically. Recently, endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have been utilized as alternative resection techniques.
AIM
OBJECTIVE
To evaluate the efficacy and safety of endoscopic resection techniques for the management of large appendiceal orifice polyps.
METHODS
METHODS
This was a retrospective observational study conducted to assess the feasibility and safety of EMR and ESD for large appendiceal orifice polyps. This project was approved by the Baylor College of Medicine Institutional Review Board. Patients who underwent endoscopic resection of appendiceal orifice polyps ≥ 1 cm from 2015 to 2022 at a tertiary referral endoscopy center in the United States were enrolled. The main outcomes of this study included
RESULTS
RESULTS
A total of 19 patients were identified. Most patients were female (53%) and Caucasian (95%). The mean age was 63.3 ± 10.8 years, and the average body mass index was 28.8 ± 6.4. The mean polyp size was 25.5 ± 14.2 mm. 74% of polyps were localized to the appendix (at or inside the appendiceal orifice) and the remaining extended into the cecum. 68% of polyps occupied ≥ 50% of the appendiceal orifice circumference. The mean procedure duration was 61.6 ± 37.9 minutes. Polyps were resected
CONCLUSION
CONCLUSIONS
Our study highlights how endoscopic mucosal resection, endoscopic submucosal dissection, and hybrid procedures are all appropriate techniques with minimal adverse effects, further validating the utility of endoscopic procedures in the management of large appendiceal polyps.
Identifiants
pubmed: 37274558
doi: 10.4253/wjge.v15.i5.386
pmc: PMC10236978
doi:
Types de publication
Journal Article
Langues
eng
Pagination
386-396Informations de copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: Tara Keihanian has received fees for serving as a consultant for Lumendi and Neptune Medical. Mohamed O Othman has received fees for serving as a consultant for Olympus America, Abbvie, Boston Scientific Corporation, Lumendi, Apollo, Conmed, and Medtronic. Mohamed O Othman has received research funding from Olympus America, Abbvie, Boston Scientific Corporation, and US Biotest.
Références
Ann Gastroenterol. 2013;26(2):114-121
pubmed: 24714799
Gastrointest Endosc. 2016 Aug;84(2):296-303.e1
pubmed: 26828760
Ann R Coll Surg Engl. 2009 Sep;91(6):456-9
pubmed: 19723418
Endoscopy. 2022 Nov;54(11):v37
pubmed: 36302356
Int J Clin Oncol. 2020 Jan;25(1):1-42
pubmed: 31203527
World J Gastroenterol. 2022 Aug 7;28(29):4007-4018
pubmed: 36157546
Dig Endosc. 2020 Jan;32(2):219-239
pubmed: 31566804
Endoscopy. 2022 Jan;54(1):16-24
pubmed: 33395714
Clin Gastroenterol Hepatol. 2020 Nov;18(12):2813-2823.e5
pubmed: 32526343
Dig Dis Sci. 2017 Nov;62(11):3138-3148
pubmed: 28936593
VideoGIE. 2020 Oct 24;6(1):38-40
pubmed: 33490755
VideoGIE. 2019 Jan 17;4(3):136-139
pubmed: 30899895
VideoGIE. 2019 Apr 23;4(6):271-273
pubmed: 31194021
Surgery. 2018 Mar;163(3):522-527
pubmed: 29361367
J Surg Oncol. 2007 Dec 15;96(8):678-83
pubmed: 18081168
J Laparoendosc Adv Surg Tech A. 2018 Oct;28(10):1188-1191
pubmed: 29727254
J Gastroenterol Hepatol. 2022 Aug;37(8):1517-1524
pubmed: 35481681
Endosc Int Open. 2020 Oct;8(10):E1273-E1279
pubmed: 33015328
Endoscopy. 2021 Apr;53(4):424-428
pubmed: 32894866
Surg Endosc. 2022 Mar;36(3):2062-2069
pubmed: 33860350
Endosc Int Open. 2018 Sep;6(9):E1112-E1119
pubmed: 30211300
JSLS. 2021 Apr-Jun;25(2):
pubmed: 34316245
Gastroenterol Res Pract. 2018 Mar 14;2018:7531368
pubmed: 29725349
Gastrointest Endosc. 2016 Mar;83(3):638-42
pubmed: 26375437
World J Gastrointest Endosc. 2009 Oct 15;1(1):45-50
pubmed: 21160650
Int J Colorectal Dis. 2019 Apr;34(4):711-718
pubmed: 30701384
Endoscopy. 2016 Sep;48(9):829-36
pubmed: 27467815