Treatment of Early Glottic cancer with Transoral Laser Microsurgery: An Australian Experience.
Carcinoma, Squamous cell
Laryngeal neoplasms
Laryngoscopy
Laser therapy
Radiotherapy
Survival analysis
Journal
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
ISSN: 2231-3796
Titre abrégé: Indian J Otolaryngol Head Neck Surg
Pays: India
ID NLM: 9422551
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
05
05
2022
accepted:
07
12
2022
pmc-release:
01
06
2024
medline:
5
6
2023
pubmed:
5
6
2023
entrez:
5
6
2023
Statut:
ppublish
Résumé
Early laryngeal carcinomas may be treated by transoral laser microsurgery (TLM) or external beam radiotherapy. We review our experience of surgical treatment of laryngeal pre-malignant and malignant lesions over the past 15 years in a high-volume head neck unit. A review of a prospective patient database of patients with laryngeal SCC, who were treated with CO 83 patients with a mean age of 67.7 (SD: 10.6) years underwent primary curative TLM for T1a/b SCC. 5-year overall survival was 93.2% (95%CI 86.9-100%), disease free survival was 86.0% (95%CI 78.1-94.6%), locoregional control was 91.2% (95%CI: 85.1-97.7%) and larynx preservation rate of 95.1% at 5 years. TLM is an excellent treatment modality for T1 early glottic SCC, with excellent locoregional control and disease-free survival. It is minimally invasive, outpatient-based, and cost-effective procedure preserving upper aerodigestive tract dysfunction for all activities of daily living.
Identifiants
pubmed: 37274960
doi: 10.1007/s12070-022-03392-8
pii: 3392
pmc: PMC10235397
doi:
Types de publication
Journal Article
Langues
eng
Pagination
661-667Informations de copyright
© Crown 2022.
Déclaration de conflit d'intérêts
Authors wish to acknowledge no conflict of interest.
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