Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung.
basal cell
bud tip progenitor
lung organoid
multiciliated cell
neuroendocrine cell
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
13 06 2023
13 06 2023
Historique:
medline:
8
6
2023
pubmed:
6
6
2023
entrez:
6
6
2023
Statut:
ppublish
Résumé
Using scRNA-seq and microscopy, we describe a cell that is enriched in the lower airways of the developing human lung and identified by the unique coexpression of
Identifiants
pubmed: 37279279
doi: 10.1073/pnas.2210113120
pmc: PMC10268599
doi:
Substances chimiques
Cystic Fibrosis Transmembrane Conductance Regulator
126880-72-6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2210113120Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL119215
Pays : United States
Organisme : NICHD NIH HHS
ID : R24 HD000836
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM145304
Pays : United States
Organisme : NHLBI NIH HHS
ID : F30 HL156474
Pays : United States
Organisme : NIDCR NIH HHS
ID : T32 DE007057
Pays : United States
Organisme : NHLBI NIH HHS
ID : F31 HL152531
Pays : United States
Organisme : NHLBI NIH HHS
ID : F31 HL142197
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007863
Pays : United States
Organisme : NHLBI NIH HHS
ID : F31 HL146162
Pays : United States
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