Metabolic dysfunction-associated fatty liver disease in people living with HIV.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
06 06 2023
Historique:
received: 04 01 2023
accepted: 05 04 2023
medline: 8 6 2023
pubmed: 7 6 2023
entrez: 6 6 2023
Statut: epublish

Résumé

The prevalence of metabolic risk factors and non-alcoholic fatty liver disease (NAFLD) is high among people living with HIV (PLWH). Data on the recently proposed definition of metabolic dysfunction-associated fatty liver disease (MAFLD) in PLWH receiving antiretroviral therapy (ART) remains unknown. A total of 282 PLWH were included in this cross-sectional cohort study. Vibration-controlled transient elastography (VCTE) was used to assess hepatic steatosis and fibrosis. MAFLD and its subgroups (overweight/obese, lean/normal weight, and type 2 diabetes) were defined according to a recently published international consensus statement. The majority of this cohort was male (n = 198, 70.2%), and the median age was 51.5 years. The median BMI was 25 kg/m

Identifiants

pubmed: 37280241
doi: 10.1038/s41598-023-32965-y
pii: 10.1038/s41598-023-32965-y
pmc: PMC10244325
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9158

Informations de copyright

© 2023. The Author(s).

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Auteurs

Maurice Michel (M)

Metabolic Liver Research Program, I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.
I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.

Christian Labenz (C)

Metabolic Liver Research Program, I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.
I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.

Angelo Armandi (A)

Metabolic Liver Research Program, I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.
Department of Medical Sciences, University of Turin, Turin, Italy.

Leonard Kaps (L)

I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.

Wolfgang Maximilian Kremer (WM)

I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.

Peter R Galle (PR)

I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.

Daniel Grimm (D)

I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.

Martin Sprinzl (M)

I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.

Jörn M Schattenberg (JM)

Metabolic Liver Research Program, I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany. joern.schattenberg@unimedizin-mainz.de.
I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany. joern.schattenberg@unimedizin-mainz.de.

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