A computationally efficient algorithm for wearable sleep staging in clinical populations.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
06 06 2023
Historique:
received: 31 01 2023
accepted: 03 06 2023
medline: 8 6 2023
pubmed: 7 6 2023
entrez: 6 6 2023
Statut: epublish

Résumé

This study describes a computationally efficient algorithm for 4-class sleep staging based on cardiac activity and body movements. Using an accelerometer to calculate gross body movements and a reflective photoplethysmographic (PPG) sensor to determine interbeat intervals and a corresponding instantaneous heart rate signal, a neural network was trained to classify between wake, combined N1 and N2, N3 and REM sleep in epochs of 30 s. The classifier was validated on a hold-out set by comparing the output against manually scored sleep stages based on polysomnography (PSG). In addition, the execution time was compared with that of a previously developed heart rate variability (HRV) feature-based sleep staging algorithm. With a median epoch-per-epoch κ of 0.638 and accuracy of 77.8% the algorithm achieved an equivalent performance when compared to the previously developed HRV-based approach, but with a 50-times faster execution time. This shows how a neural network, without leveraging any a priori knowledge of the domain, can automatically "discover" a suitable mapping between cardiac activity and body movements, and sleep stages, even in patients with different sleep pathologies. In addition to the high performance, the reduced complexity of the algorithm makes practical implementation feasible, opening up new avenues in sleep diagnostics.

Identifiants

pubmed: 37280297
doi: 10.1038/s41598-023-36444-2
pii: 10.1038/s41598-023-36444-2
pmc: PMC10244431
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9182

Informations de copyright

© 2023. The Author(s).

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Auteurs

Pedro Fonseca (P)

Philips Research Eindhoven, High Tech Campus 34, 5656AE, Eindhoven, The Netherlands. pedro.fonseca@philips.com.
Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. pedro.fonseca@philips.com.

Marco Ross (M)

Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
Sleep and Respiratory Care, Philips Austria GmbH, Vienna, Austria.

Andreas Cerny (A)

Sleep and Respiratory Care, Philips Austria GmbH, Vienna, Austria.

Peter Anderer (P)

Sleep and Respiratory Care, Philips Austria GmbH, Vienna, Austria.

Fokke van Meulen (F)

Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands.

Hennie Janssen (H)

Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands.

Angelique Pijpers (A)

Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands.

Sylvie Dujardin (S)

Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands.

Pauline van Hirtum (P)

Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands.

Merel van Gilst (M)

Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands.

Sebastiaan Overeem (S)

Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands.

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