Medication administration error prevention among nurses working in intensive care units: A secondary analysis.

cultural background intensive care unit medication error nurses prevention

Journal

Nursing in critical care
ISSN: 1478-5153
Titre abrégé: Nurs Crit Care
Pays: England
ID NLM: 9808649

Informations de publication

Date de publication:
07 Jun 2023
Historique:
revised: 12 02 2023
received: 30 09 2022
accepted: 02 05 2023
medline: 7 6 2023
pubmed: 7 6 2023
entrez: 7 6 2023
Statut: aheadofprint

Résumé

The intensive care unit (ICU) brings together high-risk patients and interventions in a complex environment. Based on this consideration, medication administration error is the most common type of error that occurs in ICUs. Literature confirms that human factors (lack of knowledge, poor practices and negative attitudes) of nurses are the main contributors to the occurrence of medication administration errors in ICUs. To examine and compare the knowledge, attitudes and behaviour scores on medication administration error according to nurses' sociodemographic and professional variables. This is a secondary analysis of data from a cross-sectional international study based on a survey. Descriptive statistics were computed for all items of the questionnaire. Non-parametric tests (Kruskal Wallis and Mann Whitney U tests) were used to carry out the comparison between groups. The international sample consisted of 1383 nurses in 12 different countries. Statistically significant changes were seen in knowledge, attitudes and behaviour scores among several subgroups of the international population. Eastern nurses were more likely to show adequate knowledge about medication administration error prevention than Western nurses; concurrently, Western nurses were significantly more likely to show positive attitudes than Eastern nurses. No statistically significant differences in the behaviour scale were found in this study. The findings show a difference between knowledge and attitudes in relation to cultural background. Decision makers in ICUs should consider cultural background when planning and implementing prevention strategies for medication administration errors. Further research is needed to investigate the effectiveness of educational systems on the decrease of the incidence of medication administration errors in ICU.

Sections du résumé

BACKGROUND BACKGROUND
The intensive care unit (ICU) brings together high-risk patients and interventions in a complex environment. Based on this consideration, medication administration error is the most common type of error that occurs in ICUs. Literature confirms that human factors (lack of knowledge, poor practices and negative attitudes) of nurses are the main contributors to the occurrence of medication administration errors in ICUs.
AIM OBJECTIVE
To examine and compare the knowledge, attitudes and behaviour scores on medication administration error according to nurses' sociodemographic and professional variables.
STUDY DESIGN METHODS
This is a secondary analysis of data from a cross-sectional international study based on a survey. Descriptive statistics were computed for all items of the questionnaire. Non-parametric tests (Kruskal Wallis and Mann Whitney U tests) were used to carry out the comparison between groups.
RESULTS RESULTS
The international sample consisted of 1383 nurses in 12 different countries. Statistically significant changes were seen in knowledge, attitudes and behaviour scores among several subgroups of the international population. Eastern nurses were more likely to show adequate knowledge about medication administration error prevention than Western nurses; concurrently, Western nurses were significantly more likely to show positive attitudes than Eastern nurses. No statistically significant differences in the behaviour scale were found in this study.
CONCLUSIONS CONCLUSIONS
The findings show a difference between knowledge and attitudes in relation to cultural background.
RELEVANCE TO CLINICAL PRACTICE CONCLUSIONS
Decision makers in ICUs should consider cultural background when planning and implementing prevention strategies for medication administration errors. Further research is needed to investigate the effectiveness of educational systems on the decrease of the incidence of medication administration errors in ICU.

Identifiants

pubmed: 37283277
doi: 10.1111/nicc.12932
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

© 2023 British Association of Critical Care Nurses.

Références

World Health Organization (WHO). Medication without harm. 2017b https://www.who.int/initiatives/medication-without-harm
World Health Organization (WHO). Patient safety making health care safer. 2017a http://apps.who.int/bookorders
Giannetta N, Dionisi S, Tonello M, Di Simone E, Di Muzio M. A worldwide bibliometric analysis of published literature on medication errors. J Patient Saf. 2022;18(3):201-209. doi:10.1097/PTS.0000000000000894
Huang HC, Wang CH, Chen PC, Lee YD. Bibliometric analysis of medication errors and adverse drug events studies. J Patient Saf. 2019;15(2):128-134.
Wondmieneh A, Alemu W, Tadele N, Demis A. Medication administration errors and contributing factors among nurses: a cross sectional study in tertiary hospitals, Addis Ababa, Ethiopia. BMC Nurs. 2020;19:4.
World Health Organization (WHO). Medication error. 2016 http://apps.who.int/bookorders
World Health Organization (WHO). Global action on patient safety. 2019 https://apps.who.int/gb/ebwha/pdf_files/WHA72/A72_R6-en.pdf?ua=1
Donchin Y, Gopher D, Olin M, et al. A look into the nature and causes of human errors in the intensive care unit. Crit Care Med. 1995;23(2):294-300. doi:10.1097/00003246-199502000-00015
Zirpe KG, Seta B, Gholap S, et al. Incidence of medication error in critical care unit of a tertiary care hospital: where do we stand? Indian J Crit Care Med Peer-Rev Off Publ Indian Soc Crit Care Med. 2020;24(9):799-803.
Dionisi S, Giannetta N, Liquori G, et al. Medication errors in intensive care units: an umbrella review of control measures. Healthcare (Basel, Switzerland). 2022;10(7):1221.
Alemu W, Belachew T, Yimam I. Medication administration errors and contributing factors: a cross sectional study in two public hospitals in Southern Ethiopia. Int J Africa Nurs Sci. 2017;7(Supplement C):68-74.
Mohammed T, Mahmud S, Gintamo B, Mekuria ZN, Gizaw Z. Medication administration errors and associated factors among nurses in Addis Ababa federal hospitals, Ethiopia: a hospital-based cross-sectional study. BMJ Open. 2022;12(12):e066531. doi:10.1136/bmjopen-2022-066531
Schroers G, Ross JG, Moriarty H. Nurses' perceived causes of medication administration errors: a qualitative systematic review. Jt Comm J Qual Patient Saf. 2020;47:38-53.
Di Muzio M, Tartaglini D, De Vito C, La Torre G. Validation of a questionnaire for ICU nurses to assess knowledge, attitudes and behaviours towards medication errors. Ann Ig. 2016a;28(2):113-121. doi:10.7416/ai.2016.2090
Di Muzio M, Marzuillo C, De Vito C, La Torre G, Tartaglini D. Knowledge, attitudes, behaviour and training needs of ICU nurses on medication errors in the use of IV drugs: a pilot study. Signa Vitae. 2016b;11(1):182-206. doi:10.22514/sv111.052016.13
Giannetta N, Dionisi S, Cassar M, et al. Measuring knowledge, attitudes and behavior of nurses in medication management: cross-cultural comparisons in Italy and Malta. Eur Rev Med Pharmacol Sci. 2020a;24(9):5167-5175. doi:10.26355/eurrev_202005_21212
Thomas B, Paudyal V, MacLure K, et al. Medication errors in hospitals in the Middle East: a systematic review of prevalence, nature, severity and contributory factors. Eur J Clin Pharmacol. 2019;75(9):1269-1282. Springer Verlag. doi:10.1007/s00228-019-02689-y
Al-Worafi YM. Medication errors. Drug Safety in Developing Countries. Elsevier; 2020a:59-71. doi:10.1016/B978-0-12-819837-7.00006-6
Al-Worafi YM. Drug safety in developing versus developed countries. Drug Safety in Developing Countries. Elsevier; 2020b:613-615. doi:10.1016/b978-0-12-819837-7.00043-1
Giannetta N, Dionisi S, Stievano A, et al. Comparison across 12 countries on knowledge, attitude, and behavior scores about medication errors in intensive care units: an international study. Eur Rev Med Pharmacol Sci. 2021;25(23):7223-7230. doi:10.26355/eurrev_202112_27415
Sharma A, Minh Duc NT, Thang, T. LL, et al. A consensus-based checklist for reporting of survey studies (CROSS). J Gen Intern Med. 2021;36(10):3179-3187. doi:10.1007/s11606-021-06737-1
World Population Review. Western Countries 2022. 2022 https://worldpopulationreview.com/country-rankings/western-countries (September 18, 2022)
Márquez-Hernández VV, Fuentes-Colmenero AL, Cañadas-Núñez F, Di Muzio M, Giannetta N, Gutiérrez-Puertas L. Factors related to medication errors in the preparation and administration of intravenous medication in the hospital environment. PLoS One. 2019;14(7):e0220001. doi:10.1371/journal.pone.0220001
Di Muzio M, De Vito C, Tartaglini D, Villari P. Knowledge, behaviours, training and attitudes of nurses during preparation and administration of intravenous medications in intensive care units (ICU). A multicenter Italian study. Appl Nurs Res. 2017;38:129-133. doi:10.1016/j.apnr.2017.10.002
Barbaranelli C, D'Olimpio F. Analisi dei dati con SPSS. Parte 1. Le Analisi di Base. Edizioni Universitarie di Lettere Economia Diritto [ed.]; Vol. 1. 1st ed. ; 2007.
Kuitunen SK, Niittynen I, Airaksinen M, Holmström AR. Systemic defenses to prevent intravenous medication errors in hospitals: a systematic review. J Patient Saf. 2021;17(8):e1669-e1680. doi:10.1097/PTS.0000000000000688
Aidah S, Gillani SW, Alderazi A, Abdulazeez F. Medication error trends in middle eastern countries: a systematic review on healthcare services. J Educ Health Promot. 2021;10:227. doi:10.4103/jehp.jehp_1549_20
Alsulami Z, Conroy S, Choonara I. Medication errors in the Middle East countries: a systematic review of the literature. Eur J Clin Pharmacol. 2013;69(4):995-1008. doi:10.1007/s00228-012-1435-y
Escrivá Gracia J, Brage Serrano R, Fernández Garrido J. Medication errors and drug knowledge gaps among critical-care nurses: a mixed multi-method study. BMC Health Serv Res. 2019;19(1):640. doi:10.1186/s12913-019-4481-7
Giannetta N, Cianciulli A, Dionisi S, Figura M, Di Simone E, Di Muzio M. Orphan drugs: an European production, research and development policies. G Ital Farm Clin. 2019;33(1):29-34. doi:10.1721/3124.31053
Bell A, Galligan L, Latham J. Numeracy in paramedic education: a literature review. Adults Learn Math Int J. 2020;15(1). ISSN 1744-1803.
Boyle MJ, Eastwood K. Drug calculation ability of qualifi ed paramedics: a pilot study. World J Emerg Med. 2018;9(1):41-45. doi:10.5847/wjem.j.1920-8642.2018.01.006
Issa MR, Abuelian A, Holmes SL, Hussein A. An evaluation of the drug calculation skills of registered nurses in the Critical Care Department at a Tertiary Hospital in KSA. Int J Nurs Stud. 2019;4(1):3. doi:10.21767/2574-2825.1000042
Salman M, Mustafa ZU, Rao AZ, et al. Serious inadequacies in high alert medication-related knowledge among Pakistani nurses: findings of a large, multicenter, cross-sectional survey. Front Pharmacol. 2020;11:1. doi:10.3389/fphar.2020.01026
Amiri P, Rahimi B, Khalkhali HR. Nurses' attitudes toward computerized provider order entry (CPOE) system: a feasibility study prior to implementation. J Clin Res Paramed Sci, (In Press). 2020. doi:10.5812/jcrps.101420
Bowman C, McKenna J, Schneider P, Barnes B. Comparison of medication history accuracy between nurses and pharmacy personnel. J Pharm Pract. 2019;32(1):62-67. doi:10.1177/0897190017739982
Hart C, Price C, Graziose G, Grey J. A program using pharmacy technicians to collect medication histories in the emergency department. P T. 2015;40(1):56-61.
Procopio GL, Faley B, Wynd MA, Finefrock D, Kobayashi M, Feldman J. Pharmacy collected medication histories in an observation unit. SAGE Open Med. 2015;3, 205031211559887. doi:10.1177/2050312115598872
Tariq RA, Sharma S. Inappropriate Medical Abbreviations. StatPearls Publishing; 2019 http://www.ncbi.nlm.nih.gov/pubmed/30085548
Giannetta N, Marson D, Della Donna E, et al. Strumenti per facilitare il processo decisionale sulla modalità di somministrazionedi infusioni in contemporanea in setting intensivi: un'esperienza italiana | Giornale Italiano di Farmacia Clinica-Rivista della Società Italiana di Farmacia Ospedaliera. G Ital Farm Clin. 2020b;34(2):62-74.
Di Muzio M, Dionisi S, Di Simone E, et al. Can nurses' shift work jeopardize the patient safety? A systematic review. Eur Rev Med Pharmacol Sci. 2019a;23(10):4507-4519. doi:10.26355/eurrev_201905_17963
Di Muzio M, Reda F, Diella G, et al. Not only a problem of fatigue and sleepiness: changes in psychomotor performance in Italian nurses across 8-h rapidly rotating shifts. J Clin Med. 2019b;8(1):47. doi:10.3390/jcm8010047
Di Simone E, Fabbian F, Giannetta N, et al. Risk of medication errors and nurses' quality of sleep: a national cross-sectional web survey study. Eur Rev Med Pharmacol Sci. 2020;24(12):7058-7062. Verduci Editore s.r.l. doi:10.26355/eurrev_202006_21699
Salami I, Subih M, Darwish R, et al. Medication administration errors. J Nurs Care Qual. 2019;34(2):E7-E12. doi:10.1097/NCQ.0000000000000340
Härkänen M, Turunen H, Vehviläinen-Julkunen K. Differences between methods of detecting medication errors: a secondary analysis of medication administration errors using incident reports, the global trigger tool method, and observations. J Patient Saf. 2020;16(2):168-176. doi:10.1097/PTS.0000000000000261
Salar A, Kiani F, Rezaee N. Preventing the medication errors in hospitals: a qualitative study. Int J Africa Nurs Sci. 2020;13:100235. doi:10.1016/j.ijans.2020.100235
Ghodousi A, Shahrokhi A, Ebrahimpour F. Factors effective on medication errors: a nursing view. J Res Pharm Pract. 2013;2(1):18-23. doi:10.4103/2279-042x.114084
Jember A, Hailu M, Messele A, Demeke T, Hassen M. Proportion of medication error reporting and associated factors among nurses: a cross sectional study. BMC Nurs. 2018;17(1):9. doi:10.1186/s12912-018-0280-4
Alrabadi N, Haddad R, Haddad R, et al. Medication errors among registered nurses in Jordan. J Pharm Health Serv Res. 2020;11(3):237-243. doi:10.1111/jphs.12348
Feleke SA, Mulatu MA, Yesmaw YS. Medication administration error: magnitude and associated factors among nurses in Ethiopia. BMC Nurs. 2015;14(1):53. doi:10.1186/s12912-015-0099-1
Kareem AG, Zaki SD. Evaluation of nurses practices regarding intravenous medications administration at Raparin Pediatric Teaching Hospital/Erbil city. J Nurs Sci. 2018;7(2):108-116. http://journals.uokufa.edu.iq/index.php/kjns/article/view/6492
Sutherland A, Canobbio M, Clarke J, Randall M, Skelland T, Weston E. Incidence and prevalence of intravenous medication errors in the UK: a systematic review. Eur J Hosp Pharm. 2018;0:1-6. doi:10.1136/ejhpharm-2018-001624
Alefan Q, Halboup A, Battah M. Drug safety in Jordan. Drug Safety in Developing Countries. Elsevier; 2020:429-447. doi:10.1016/b978-0-12-819837-7.00032-7
Chan, D. (2009). So Why Ask Me? Are Self-Report Data Really that Bad? Statistical and Methodological Myths and Urban Legends: Doctrine, Verity, and Fable in the Organizational and Social Sciences. Routledge/Taylor & Francis Group. https://ink.library.smu.edu.sg/soss_research/544

Auteurs

Noemi Giannetta (N)

UniCamillus-Saint Camillus International University of Health and Medical Sciences, Rome, Italy.

Josef Trapani (J)

Department of Nursing, University of Malta, L-Imsida, Malta.

Sara Dionisi (S)

AUSL Bologna, Area DATeR Integration of Continuity of Care, Bologna, Italy.

Aurora De Leo (A)

Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Nursing, Technical, Rehabilitation, Assistance and Research Direction, IRCCS Istituti Fisioterapici Ospitalieri-IFO, Rome, Italy.

Fabrizio Petrone (F)

Nursing, Technical, Rehabilitation, Assistance and Research Direction, IRCCS Istituti Fisioterapici Ospitalieri-IFO, Rome, Italy.

Fabio D'Agostino (F)

UniCamillus-Saint Camillus International University of Health and Medical Sciences, Rome, Italy.

Gloria Liquori (G)

Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.

Emanuele Di Simone (E)

Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.

Maria Cassar (M)

Department of Nursing, University of Malta, L-Imsida, Malta.

Marco Di Muzio (M)

Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.

Classifications MeSH