Feedback Inhibition of Bacterial Nucleotidyltransferases by Rare Nucleotide l-Sugars Restricts Substrate Promiscuity.


Journal

Journal of the American Chemical Society
ISSN: 1520-5126
Titre abrégé: J Am Chem Soc
Pays: United States
ID NLM: 7503056

Informations de publication

Date de publication:
26 07 2023
Historique:
medline: 27 7 2023
pubmed: 7 6 2023
entrez: 7 6 2023
Statut: ppublish

Résumé

Bacterial glycomes are rich in prokaryote-specific or "rare" sugars that are absent in mammals. Like common sugars found across organisms, rare sugars are typically activated as nucleoside diphosphate sugars (NDP-sugars) by nucleotidyltransferases. In bacteria, the nucleotidyltransferase RmlA initiates the production of several rare NDP-sugars, which in turn regulate downstream glycan assembly through feedback inhibition of RmlA via binding to an allosteric site.

Identifiants

pubmed: 37283497
doi: 10.1021/jacs.3c02319
pmc: PMC10375476
doi:

Substances chimiques

Nucleotides 0
Nucleotidyltransferases EC 2.7.7.-
Sugars 0
Nucleoside Diphosphate Sugars 0

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

15632-15638

Références

Org Lett. 2002 Nov 14;4(23):3997-4000
pubmed: 12423070
Bioorg Med Chem. 2012 Nov 1;20(21):6403-15
pubmed: 23000295
Appl Environ Microbiol. 2002 Aug;68(8):3708-15
pubmed: 12147463
J Biol Chem. 2011 Apr 15;286(15):13235-43
pubmed: 21317292
Bioorg Med Chem. 1997 Feb;5(2):383-91
pubmed: 9061202
Angew Chem Int Ed Engl. 2001 Apr 17;40(8):1502-1505
pubmed: 29712364
Curr Opin Struct Biol. 2000 Dec;10(6):687-96
pubmed: 11114506
J Org Chem. 2022 Apr 15;87(8):5315-5327
pubmed: 35363473
ACS Chem Biol. 2013 Feb 15;8(2):387-96
pubmed: 23138692
ACS Infect Dis. 2022 Oct 14;8(10):2035-2044
pubmed: 36106727
Chem Asian J. 2016 Dec 6;11(23):3398-3413
pubmed: 27685372
ACS Chem Biol. 2007 Oct 19;2(10):685-91
pubmed: 18041818
J Org Chem. 2005 Sep 30;70(20):8064-70
pubmed: 16277328
Curr Opin Microbiol. 2021 Jun;61:16-24
pubmed: 33662818
Cold Spring Harb Perspect Biol. 2010 May;2(5):a000414
pubmed: 20452953
Carbohydr Res. 1991 Sep 2;216:337-55
pubmed: 1724632
Chem Rev. 2000 Dec 13;100(12):4589-614
pubmed: 11749359
J Am Chem Soc. 2022 Jun 8;144(22):9980-9989
pubmed: 35583341
FEMS Microbiol Rev. 2016 Jul;40(4):464-79
pubmed: 26975195
Protein Sci. 2008 Mar;17(3):577-82
pubmed: 18218712
Org Lett. 2014 Nov 7;16(21):5628-31
pubmed: 25312597
Bioorg Med Chem. 2021 Nov 15;50:116477
pubmed: 34757294
ACS Chem Biol. 2021 Oct 15;16(10):1841-1865
pubmed: 34569792
Bioorg Med Chem Lett. 2011 Sep 1;21(17):5050-3
pubmed: 21592792
Bioorg Med Chem. 2021 Jul 15;42:116268
pubmed: 34130219
Carbohydr Res. 2003 Nov 14;338(23):2503-19
pubmed: 14670712
FEMS Microbiol Lett. 2007 Oct;275(2):237-43
pubmed: 17784859
Nucleosides Nucleotides Nucleic Acids. 2012;31(7):567-73
pubmed: 22849648
J Org Chem. 1998 Oct 16;63(21):7568-7572
pubmed: 11672420
Bioorg Med Chem Lett. 2011 Jul 1;21(13):3914-7
pubmed: 21640586
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13397-402
pubmed: 12374866
J Biol Chem. 2007 Jun 8;282(23):16942-7
pubmed: 17434871
BMC Struct Biol. 2008 Aug 11;8:35
pubmed: 18694500
J Biol Chem. 1982 Aug 25;257(16):9759-69
pubmed: 6286632
J Biol Chem. 1965 Jan;240:398-405
pubmed: 14253442
Nat Prod Rep. 2009 Sep;26(9):1172-94
pubmed: 19693414
Nature. 2020 Feb;578(7795):403-408
pubmed: 31940659
Angew Chem Int Ed Engl. 2008;47(51):9814-59
pubmed: 19058170
Angew Chem Int Ed Engl. 2023 May 8;62(20):e202217894
pubmed: 36840742
Chem Soc Rev. 2021 Sep 20;50(18):10212-10252
pubmed: 34542133
Curr Opin Chem Biol. 2019 Dec;53:1-8
pubmed: 31176085
Nat Prod Rep. 2011 Oct;28(11):1811-53
pubmed: 21901218
Carbohydr Res. 2010 Sep 3;345(13):1958-62
pubmed: 20667525
J Org Chem. 2013 Oct 4;78(19):9822-33
pubmed: 24020932
Nat Struct Biol. 2001 Jun;8(6):545-51
pubmed: 11373625
Biochem J. 2021 Feb 26;478(4):685-701
pubmed: 33599745
Carbohydr Res. 1986 Nov 15;156:39-56
pubmed: 3815408
Chem Commun (Camb). 2014 May 11;50(36):4659-73
pubmed: 24647371
J Biol Chem. 1965 Jan;240:391-7
pubmed: 14253441
EMBO J. 2000 Dec 15;19(24):6652-63
pubmed: 11118200
Carbohydr Res. 2008 Apr 7;343(5):865-74
pubmed: 18299123
J Bacteriol. 1994 Sep;176(18):5788-95
pubmed: 8083170
J Biol Chem. 2017 Apr 14;292(15):6255-6268
pubmed: 28223362
Org Lett. 2004 Aug 19;6(17):2873-6
pubmed: 15330636
J Biol Chem. 1973 Sep 10;248(17):6041-9
pubmed: 4199258
J Biol Chem. 2019 Jun 7;294(23):9172-9185
pubmed: 31010825

Auteurs

Meng Zheng (M)

Department of Chemistry, New York University, New York, New York 10003, United States.

Maggie C Zheng (MC)

Department of Chemistry, New York University, New York, New York 10003, United States.

Hanee Kim (H)

Department of Chemistry, New York University, New York, New York 10003, United States.

Tania J Lupoli (TJ)

Department of Chemistry, New York University, New York, New York 10003, United States.

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Classifications MeSH