Oligometastasis in Prostate Cancer: Can We Learn from Those "Excluded" from a Phase 2 Trial?

Metastasis-directed therapy Oligometastasis Positron emission tomography Prostate cancer Prostate-specific membrane antigen

Journal

European urology open science
ISSN: 2666-1683
Titre abrégé: Eur Urol Open Sci
Pays: Netherlands
ID NLM: 101771568

Informations de publication

Date de publication:
Jun 2023
Historique:
accepted: 24 03 2023
medline: 7 6 2023
pubmed: 7 6 2023
entrez: 7 6 2023
Statut: epublish

Résumé

We conducted and previously published a phase 2 trial of metastasis-directed therapy (MDT) in men with recurrence of prostate cancer at a low prostate-specific antigen level following radical prostatectomy and postoperative radiotherapy. All patients had negative conventional imaging and underwent prostate-specific membrane antigen (PSMA) positron emission tomography (PET). Patients without visible disease ( In men with prostate cancer with rising PSA levels following surgery and radiation, a newer type of scan called PSMA-PET (prostate-specific membrane antigen positron emission tomography) can be used to characterize and differentiate the patterns of recurrence, and inform future cancer outcomes.

Identifiants

pubmed: 37284049
doi: 10.1016/j.euros.2023.03.016
pii: S2666-1683(23)00201-X
pmc: PMC10240507
doi:

Types de publication

Journal Article

Langues

eng

Pagination

79-84

Informations de copyright

© 2023 The Author(s).

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Auteurs

Rachel M Glicksman (RM)

Department of Radiation Oncology, University of Toronto, Toronto, Canada.
Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.

Vanessa Murad (V)

Joint Department of Medical Imaging, University Health Network, Mount Sinai Hospital and Women's College Hospital, University of Toronto, Toronto, Canada.

Anna T Santiago (AT)

Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.

Zhihui Liu (Z)

Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

Matthew Ramotar (M)

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.

Ur Metser (U)

Joint Department of Medical Imaging, University Health Network, Mount Sinai Hospital and Women's College Hospital, University of Toronto, Toronto, Canada.

Alejandro Berlin (A)

Department of Radiation Oncology, University of Toronto, Toronto, Canada.
Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
TECHNA Institute, University Health Network, University of Toronto, Toronto, Canada.

Classifications MeSH