Endobronchial Ultrasound is Useful in the Assessment of Bronchial Wall Changes Related to Bronchial Thermoplasty.
airway remodeling
airway smooth muscle
bronchial thermoplasty
bronchial wall layers
endobronchial ultrasound
Journal
Journal of asthma and allergy
ISSN: 1178-6965
Titre abrégé: J Asthma Allergy
Pays: New Zealand
ID NLM: 101543450
Informations de publication
Date de publication:
2023
2023
Historique:
received:
10
01
2023
accepted:
07
04
2023
medline:
7
6
2023
pubmed:
7
6
2023
entrez:
7
6
2023
Statut:
epublish
Résumé
Bronchial thermoplasty (BT) is an interventional endoscopic treatment for severe asthma leading to the clinical improvement, but morphologic changes of bronchial wall related to the procedure and predictors of a favorable response to BT remain uncertain. The aim of the study was to validate an endobronchial ultrasound (EBUS) in assessing the effectiveness of BT treatment. Patients with severe asthma who met the clinical criteria for BT were included. In all patients clinical data, ACT and AQLQ questionnaires, laboratory tests, pulmonary function tests and bronchoscopy with radial probe EBUS and bronchial biopsies were collected. BT was performed in patients with the thickest bronchial wall L Forty patients with severe asthma were enrolled to the study. All 11 patients qualified to BT successfully completed the 3 sessions of bronchoscopy. BT improved asthma control ( BT was associated with a significant decrease in the thickness of the bronchial wall layers measured by EBUS including L
Sections du résumé
Background
UNASSIGNED
Bronchial thermoplasty (BT) is an interventional endoscopic treatment for severe asthma leading to the clinical improvement, but morphologic changes of bronchial wall related to the procedure and predictors of a favorable response to BT remain uncertain. The aim of the study was to validate an endobronchial ultrasound (EBUS) in assessing the effectiveness of BT treatment.
Methods
UNASSIGNED
Patients with severe asthma who met the clinical criteria for BT were included. In all patients clinical data, ACT and AQLQ questionnaires, laboratory tests, pulmonary function tests and bronchoscopy with radial probe EBUS and bronchial biopsies were collected. BT was performed in patients with the thickest bronchial wall L
Results
UNASSIGNED
Forty patients with severe asthma were enrolled to the study. All 11 patients qualified to BT successfully completed the 3 sessions of bronchoscopy. BT improved asthma control (
Conclusion
UNASSIGNED
BT was associated with a significant decrease in the thickness of the bronchial wall layers measured by EBUS including L
Identifiants
pubmed: 37284335
doi: 10.2147/JAA.S404254
pii: 404254
pmc: PMC10241211
doi:
Types de publication
Journal Article
Langues
eng
Pagination
585-595Informations de copyright
© 2023 Soja et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
Références
Respir Res. 2021 Jun 28;22(1):186
pubmed: 34183014
Respir Med. 2016 Aug;117:131-8
pubmed: 27492523
Clin Exp Allergy. 2019 Apr;49(4):541-544
pubmed: 30723963
Allergy. 2007 Feb;62(2):126-33
pubmed: 17298420
Respir Res. 2017 Jul 4;18(1):134
pubmed: 28676053
Ann Am Thorac Soc. 2015 Nov;12(11):1612-8
pubmed: 26325484
J Asthma Allergy. 2021 Jun 14;14:663-674
pubmed: 34163179
Respiration. 2018;95(5):289-300
pubmed: 29669351
Respiration. 2018;96(6):564-570
pubmed: 30110691
Chest. 2005 Jun;127(6):1999-2006
pubmed: 15947312
J Allergy Clin Immunol. 2017 Apr;139(4):1176-1185
pubmed: 27609656
BMC Pulm Med. 2018 Feb 8;18(1):29
pubmed: 29422039
Eur J Radiol. 2018 Oct;107:33-38
pubmed: 30292270
N Engl J Med. 2007 Mar 29;356(13):1327-37
pubmed: 17392302
Pneumonol Alergol Pol. 2009;77(3):256-63
pubmed: 19591096
Am J Respir Crit Care Med. 2007 Dec 15;176(12):1185-91
pubmed: 17901415
Am J Respir Crit Care Med. 2003 Jan 1;167(1):78-82
pubmed: 12502479
Respir Med Case Rep. 2022 Jan 05;36:101571
pubmed: 35036303
Ann Am Thorac Soc. 2016 Aug;13(8):1426-8
pubmed: 27509158
Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 2):S28-38
pubmed: 11734464
Respirology. 2011 Jan;16(1):34-43
pubmed: 21044229
Eur Respir J. 2018 May 24;51(5):
pubmed: 29700102
J Appl Physiol (1985). 2004 Nov;97(5):1946-53
pubmed: 15258133
Chest. 2009 Sep;136(3):797-804
pubmed: 19429721
J Bronchology Interv Pulmonol. 2010 Oct;17(4):301-6
pubmed: 23168950
Lancet. 2012 Aug 18;380(9842):651-9
pubmed: 22901886
Eur Respir J. 2015 Sep;46(3):859-62
pubmed: 26022958
Chest. 2002 Dec;122(6 Suppl):271S-275S
pubmed: 12475796
J Allergy Clin Immunol. 2005 Sep;116(3):544-9
pubmed: 16159622
J Allergy Clin Immunol. 2015 Apr;135(4):896-902
pubmed: 25441637
Eur Respir J. 2014 Feb;43(2):343-73
pubmed: 24337046
Am J Respir Crit Care Med. 2019 Feb 15;199(4):536-538
pubmed: 30540915
Eur Respir J. 2004 Oct;24(4):659-63
pubmed: 15459147
Eur Respir J. 2008 Aug;32(2):265-74
pubmed: 18669785
Allergy Asthma Proc. 2008 Jul-Aug;29(4):365-70
pubmed: 18702882
Chest. 2022 Mar;161(3):614-628
pubmed: 34774528
Eur Respir J. 2001 Aug;18(2):254-61
pubmed: 11529281
Chest. 2021 Aug;160(2):432-435
pubmed: 33785301
PLoS One. 2017 Oct 5;12(10):e0184145
pubmed: 28981500
Eur Respir J. 2021 Dec 31;59(1):
pubmed: 34049950
J Allergy Clin Immunol. 2021 Nov;148(5):1227-1235.e6
pubmed: 33453288
Am Rev Respir Dis. 1987 Oct;136(4):1066
pubmed: 3662229
Am J Respir Crit Care Med. 2010 Jan 15;181(2):116-24
pubmed: 19815809
AJR Am J Roentgenol. 2017 Oct;209(4):752-756
pubmed: 28796545
Intern Med. 2019 Jun 1;58(11):1613-1616
pubmed: 30713306
PLoS One. 2015 Sep 08;10(9):e0136284
pubmed: 26348727
Eur Respir J. 2009 Nov;34(5):1040-5
pubmed: 19282340
Thorax. 1998 Apr;53(4):248-53
pubmed: 9741365
Am J Respir Crit Care Med. 2021 Jan 15;203(2):175-184
pubmed: 32721210