The sublingual microcirculation and frailty index in chronic kidney disease patients.
frailty
frailty index
kidney disease
microcirculation
sublingual
Journal
Microcirculation (New York, N.Y. : 1994)
ISSN: 1549-8719
Titre abrégé: Microcirculation
Pays: United States
ID NLM: 9434935
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
revised:
18
05
2023
received:
27
03
2023
accepted:
25
05
2023
medline:
14
8
2023
pubmed:
7
6
2023
entrez:
7
6
2023
Statut:
ppublish
Résumé
To examine the relationship between sublingual microcirculatory measures and frailty index in those attending a kidney transplant assessment clinic. Patients recruited had their sublingual microcirculation taken using sidestream dark field videomicroscopy (MicroScan, Micro Vision Medical, Amsterdam, the Netherlands) and their frailty index score using a validated short form via interview. A total of 44 patients were recruited with two being excluded due to microcirculatory image quality scores exceeding 10. The frailty index score indicated significant correlations with total vessel density (p < .0001, r = -.56), microvascular flow index (p = .004, r = -.43), portion of perfused vessels (p = .0004, r = -.52), heterogeneity index (p = .015, r = .32), and perfused vessel density (p < .0001, r = -.66). No correlation was shown between the frailty index and age (p = .08, r = .27). There is a relationship between the frailty index and microcirculatory health in those attending a kidney transplant assessment clinic, that is not confounded by age. These findings suggest that the impaired microcirculation may be an underlying cause of frailty.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12819Informations de copyright
© 2023 The Authors. Microcirculation published by John Wiley & Sons Ltd.
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