To TIPS or Not to TIPS in High Risk of Variceal Rebleeding and Acute-on-Chronic Liver Failure.
Journal
Seminars in liver disease
ISSN: 1098-8971
Titre abrégé: Semin Liver Dis
Pays: United States
ID NLM: 8110297
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
medline:
17
7
2023
pubmed:
8
6
2023
entrez:
7
6
2023
Statut:
ppublish
Résumé
Variceal bleeding is a consequence of severe portal hypertension in patients with liver cirrhosis. Although the rate of bleeding has decreased over time, variceal bleeding in the presence of acute-on-chronic liver failure (ACLF) carries a high risk of treatment failure and short-term mortality. Treatment and/or removal of precipitating events (mainly bacterial infection and alcoholic hepatitis) and decrease of portal pressure may improve outcome of patients with acute decompensation or ACLF. Transjugular intrahepatic portosystemic shunts (TIPSs), especially in the preemptive situation, have been found to efficiently control bleeding, prevent rebleeding, and reduce short-term mortality. Therefore, TIPS placement should be considered
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
189-205Subventions
Organisme : European Union's Horizon 2020 research and innovation program
ID : DECISION (project ID: 847949)
Organisme : European Union's Horizon 2020 research and innovation program
ID : GALAXY (project ID: 668031)
Organisme : European Union's Horizon 2020 research and innovation program
ID : IHMCSA (project ID: 964590)
Organisme : European Union's Horizon 2020 research and innovation program
ID : LIVERHOPE (project ID: 731875)
Organisme : European Union's Horizon 2020 research and innovation program
ID : MICROB-PREDICT (project ID: 825694)
Organisme : German Federal Ministry of Education and Research (BMBF)
ID : DEEP-HCC project
Organisme : German Research Foundation (DFG) project
ID : ID 403224013-SFB 1382 (A09)
Organisme : Hessian Ministry of Higher Education, Research and the Arts (HMWK)
ID : ACLF-I
Organisme : Hessian Ministry of Higher Education, Research and the Arts (HMWK)
ID : ENABLE
Informations de copyright
Thieme. All rights reserved.
Déclaration de conflit d'intérêts
J.T. has received speaking and/or consulting fees from Gore, Alexion, MSD, Grifols, Versantis, and CSL Behring. W.L. has received consultancy fees from CSL Behring, Cook Medical, Boston-Scientific, and Norgine.