The clinical and genomic features of seizures in meningiomas.

NF2 meningioma seizures

Journal

Neuro-oncology advances
ISSN: 2632-2498
Titre abrégé: Neurooncol Adv
Pays: England
ID NLM: 101755003

Informations de publication

Date de publication:
May 2023
Historique:
medline: 8 6 2023
pubmed: 8 6 2023
entrez: 8 6 2023
Statut: epublish

Résumé

Meningiomas are the most common central nervous system tumors. Although these tumors are extra-axial, a relatively high proportion (10%-50%) of meningioma patients have seizures that can substantially impact the quality of life. Meningiomas are believed to cause seizures by inducing cortical hyperexcitability that results from mass effect and cortical irritation, brain invasion, or peritumoral brain edema. In general, meningiomas that are associated with seizures have aggressive features, with risk factors including atypical histology, brain invasion, and higher tumor grade. Somatic

Identifiants

pubmed: 37287582
doi: 10.1093/noajnl/vdac110
pii: vdac110
pmc: PMC10243847
doi:

Types de publication

Journal Article

Langues

eng

Pagination

i49-i57

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

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Auteurs

Alper Dincer (A)

Department of Neurosurgery, Tufts Medical Center, Boston, Massachusetts, USA.

Muhammad I Jalal (MI)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Trisha P Gupte (TP)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Shaurey Vetsa (S)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Sagar Vasandani (S)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Kanat Yalcin (K)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Neelan Marianayagam (N)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Nicholas Blondin (N)

Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA.

Zachary Corbin (Z)

Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA.

Declan McGuone (D)

Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Department of Pathology, Yale School of Medicine, New Haven, Connecticut, USA.

Robert K Fulbright (RK)

Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.

Zeynep Erson-Omay (Z)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Murat Günel (M)

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA.
Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.
Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA.

Jennifer Moliterno (J)

Chenevert Family Brain Tumor Center, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut, USA.

Classifications MeSH