Cohort profile: the BABY1000 pilot prospective longitudinal birth cohort study based in Sydney, Australia.
COVID-19
maternal medicine
paediatrics
public health
reproductive medicine
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
08 06 2023
08 06 2023
Historique:
medline:
12
6
2023
pubmed:
9
6
2023
entrez:
8
6
2023
Statut:
epublish
Résumé
The health of parents prior to conception, a woman's health during pregnancy and the infant's environment across their first months and years collectively have profound effects on the child's health across the lifespan. Since there are very few cohort studies in early pregnancy, gaps remain in our understanding of the mechanisms underpinning these relationships, and how health may be optimised. 'BABY1000', a pilot prospective longitudinal birth cohort study, aims to (1) identify factors before and during pregnancy and early life that impact longer-term health and (2) assess the feasibility and acceptability of study design to inform future research. Participants were based in Sydney, Australia. Women were recruited at preconception or 12 weeks' gestation, and data were collected from them throughout pregnancy and postpartum, their children until the age of 2 years, and dietary information from a partner (if able) at the last study visit. The pilot aimed to recruit 250 women. However, recruitment ceased earlier than planned secondary to limitations from the COVID-19 pandemic and the final number of subjects was 225. Biosamples, clinical measurements and sociodemographic/psychosocial measures were collected using validated tools and questionnaires. Data analysis and 24-month follow-up assessments for children are ongoing. Key early findings presented include participant demographics and dietary adequacy during pregnancy. The COVID-19 pandemic and associated public health and research restrictions affected recruitment of participants, follow-up assessments and data completeness. The BABY1000 study will provide further insight into the developmental origins of health and disease and inform design and implementation of future cohort and intervention studies in the field. Since the BABY1000 pilot was conducted across the COVID-19 pandemic, it also provides unique insight into the early impacts of the pandemic on families, which may have effects on health across the lifespan.
Identifiants
pubmed: 37290940
pii: bmjopen-2022-068275
doi: 10.1136/bmjopen-2022-068275
pmc: PMC10255277
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e068275Informations de copyright
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Cochrane Database Syst Rev. 2016 Nov 09;11:CD001688
pubmed: 27827515
Clin Nutr. 2014 Oct;33(5):906-14
pubmed: 24144913
Adv Neonatal Care. 2015 Dec;15(6):377-85
pubmed: 26317856
BMJ. 2016 Oct 24;355:i5239
pubmed: 27777223
Annu Rev Public Health. 2013;34:7-28
pubmed: 23514315
Nutrients. 2017 Aug 17;9(8):
pubmed: 28817083
Paediatr Perinat Epidemiol. 2012 Jul;26 Suppl 1:285-301
pubmed: 22742616
Nutrients. 2020 Nov 17;12(11):
pubmed: 33213030
Int J Obes (Lond). 2016 Jul;40(7):1056-62
pubmed: 27133623
J Clin Sleep Med. 2016 Jun 15;12(6):871-7
pubmed: 27070246
Nutr Rev. 2017 Dec 1;75(12):951-970
pubmed: 29186623
BMJ Open. 2021 Jun 24;11(6):e044463
pubmed: 34168023
Annu Rev Nutr. 2007;27:363-88
pubmed: 17465856
Nutrients. 2021 Sep 15;13(9):
pubmed: 34579077
J Clin Endocrinol Metab. 2007 Jan;92(1):98-103
pubmed: 17032722
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Transl Psychiatry. 2016 Nov 1;6(11):e936
pubmed: 27801895
Diabetes Metab Syndr. 2017 Dec;11 Suppl 2:S655-S662
pubmed: 28533070
BMC Med Res Methodol. 2020 Sep 24;20(1):238
pubmed: 32972373
J Nutr. 2016 Jul;146(7):1437S-44S
pubmed: 27281808
Lancet. 2016 Jan 30;387(10017):491-504
pubmed: 26869576
J Clin Epidemiol. 2011 Apr;64(4):395-400
pubmed: 21194891
Best Pract Res Clin Endocrinol Metab. 2012 Oct;26(5):627-39
pubmed: 22980045
Physiology (Bethesda). 2015 May;30(3):224-31
pubmed: 25933822
BMJ. 2017 Feb 8;356:j1
pubmed: 28179267
Bioessays. 2018 Jan;40(1):
pubmed: 29168895
Lancet. 2004 Nov 27-Dec 3;364(9449):1923-4
pubmed: 15566996
Trends Microbiol. 2019 Feb;27(2):131-147
pubmed: 30529020
Am J Clin Nutr. 2014 Jul;100(1):233-40
pubmed: 24787491
Prog Biophys Mol Biol. 2015 Jul;118(1-2):55-68
pubmed: 25792090
Nutr Diet. 2022 Nov;79(5):602-615
pubmed: 35355379
Lancet. 2016 Apr 2;387(10026):1377-1396
pubmed: 27115820
J Nutr. 2015 Dec;145(12):2639-45
pubmed: 26468491
Epigenomics. 2011 Jun;3(3):279-94
pubmed: 22122338
Epidemiology. 2004 Sep;15(5):550-6
pubmed: 15308954
Clin Perinatol. 2018 Jun;45(2):339-355
pubmed: 29747892
Nutrients. 2015 Jan 23;7(2):785-98
pubmed: 25625814
J Epidemiol Community Health. 2017 Feb;71(2):162-173
pubmed: 27480843
BJOG. 2008 Sep;115(10):1243-9
pubmed: 18715409
Obes Rev. 2018 Apr;19(4):464-484
pubmed: 29164765
Cochrane Database Syst Rev. 2022 Oct 25;10:CD001141
pubmed: 36282618
Int J Obes (Lond). 2013 Oct;37(10):1295-306
pubmed: 23736360
J Am Coll Dent. 2014 Summer;81(3):14-8
pubmed: 25951678
Exerc Sport Sci Rev. 2015 Oct;43(4):198-203
pubmed: 26196867
Reproduction. 2013 Oct 01;146(5):R175-89
pubmed: 23901130
BMJ. 2008 May 3;336(7651):995-8
pubmed: 18456631
Curr Diab Rep. 2017 Feb;17(2):11
pubmed: 28176229
Sleep Med Rev. 2010 Apr;14(2):107-14
pubmed: 19625199
Pediatrics. 2018 Apr;141(4):
pubmed: 29519955
PLoS One. 2016 Mar 15;11(3):e0150205
pubmed: 26978655
Lancet Diabetes Endocrinol. 2016 Dec;4(12):1025-1036
pubmed: 27743975
Lancet. 2010 Aug 28;376(9742):667-9
pubmed: 20801389