Creation of EGD-Derived Gastric Cancer Organoids to Predict Treatment Responses.
chemoresistance
gastric cancer
organoids
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
02 Jun 2023
02 Jun 2023
Historique:
received:
10
05
2023
revised:
25
05
2023
accepted:
31
05
2023
medline:
10
6
2023
pubmed:
10
6
2023
entrez:
10
6
2023
Statut:
epublish
Résumé
Gastric adenocarcinoma (GAd) is the third leading cause of cancer-related deaths worldwide. Most patients require perioperative chemotherapy, yet methods to accurately predict responses to therapy are lacking. Thus, patients may be unnecessarily exposed to considerable toxicities. Here, we present a novel methodology using patient-derived organoids (PDOs) that rapidly and accurately predicts the chemotherapy efficacy for GAd patients.
Identifiants
pubmed: 37296998
pii: cancers15113036
doi: 10.3390/cancers15113036
pmc: PMC10252567
pii:
doi:
Types de publication
Journal Article
Langues
eng
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