Behçet's Disease Uveitis.
Behçet’s disease
anti TNF-α agents
biotherapies
uveitis
vasculitis
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
24 May 2023
24 May 2023
Historique:
received:
12
03
2023
revised:
26
04
2023
accepted:
20
05
2023
medline:
10
6
2023
pubmed:
10
6
2023
entrez:
10
6
2023
Statut:
epublish
Résumé
Uveitis in Behçet's disease (BD) is frequent (40% of cases) and is a major cause of morbidity. The age of onset of uveitis is between 20 and 30 years. Ocular involvement includes anterior, posterior, or panuveitis. Uveitis may be the first sign of the disease in 20% of cases or it may appear 2 or 3 years after the first symptoms. Panuveitis is the most common presentation and is more commonly found in men. Bilateralization usually occurs on average 2 years after the first symptoms. The estimated risk of blindness at 5 years is 10-15%. BD uveitis has several ophthalmological features that distinguish it from other uveitis. The main goals in the management of patients are the rapid resolution of intraocular inflammation, the prevention of recurrent attacks, the achievement of complete remission, and the preservation of vision. Biologic therapies have changed the management of intraocular inflammation. The aim of this review is to provide an update to a previous article by our team on pathogenesis, diagnostic approaches, and the therapeutic strategy of BD uveitis.
Identifiants
pubmed: 37297843
pii: jcm12113648
doi: 10.3390/jcm12113648
pmc: PMC10253549
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Drug Ther Bull. 2018 Apr;56(4):38
pubmed: 29519948
Ocul Immunol Inflamm. 2018;26(7):1005-1014
pubmed: 29020500
Jpn J Ophthalmol. 2014 Mar;58(2):120-30
pubmed: 24482146
Retina. 2021 Aug 1;41(8):1739-1747
pubmed: 33394998
Expert Opin Biol Ther. 2019 May;19(5):477-490
pubmed: 30888881
Ann Med Interne (Paris). 1999 Nov;150(7):529-34
pubmed: 10637668
Ocul Immunol Inflamm. 2014 Apr;22(2):90-5
pubmed: 24143896
J Clin Med. 2021 May 26;10(11):
pubmed: 34073249
Rev Med Interne. 2018 Sep;39(9):738-745
pubmed: 29625716
Ann Rheum Dis. 2007 Apr;66(4):565-6
pubmed: 17124248
Clin Exp Rheumatol. 2013 Mar-Apr;31(2):320-1
pubmed: 23331715
Br J Ophthalmol. 2003 Apr;87(4):423-31
pubmed: 12642304
J Ocul Pharmacol Ther. 2008 Jun;24(3):351-61
pubmed: 18476805
Rheumatology (Oxford). 2013 May;52(5):800-5
pubmed: 23325038
Ann Rheum Dis. 2018 Jun;77(6):808-818
pubmed: 29625968
Ocul Immunol Inflamm. 2017 Feb;25(1):7-19
pubmed: 27541278
N Engl J Med. 1990 Feb 1;322(5):281-5
pubmed: 2404204
J Immunol Res. 2015;2015:705831
pubmed: 26539557
Acta Ophthalmol Scand. 1998 Feb;76(1):96-9
pubmed: 9541443
Graefes Arch Clin Exp Ophthalmol. 2006 Dec;244(12):1692-5
pubmed: 16673135
Ocul Immunol Inflamm. 2021 Apr 3;29(3):524-529
pubmed: 31743043
Arthritis Rheum. 1985 Jun;28(6):671-9
pubmed: 4004976
Arch Ophthalmol. 2011 Mar;129(3):288-94
pubmed: 21402983
Prog Retin Eye Res. 2021 Jan;80:100866
pubmed: 32422390
N Engl J Med. 2015 Apr 16;372(16):1510-8
pubmed: 25875256
Nat Genet. 2010 Aug;42(8):698-702
pubmed: 20622878
N Engl J Med. 2019 Nov 14;381(20):1918-1928
pubmed: 31722152
Circulation. 2016 Jan 19;133(3):302-11
pubmed: 26585672
Rheumatol Int. 2018 Jan;38(1):25-35
pubmed: 28752230
Eye (Lond). 2021 Oct;35(10):2719-2726
pubmed: 33235340
Histopathology. 2000 Apr;36(4):362-71
pubmed: 10759951
Clin Rheumatol. 2017 Jan;36(1):191-197
pubmed: 27981463
Inflammopharmacology. 2020 Jun;28(3):711-718
pubmed: 32157555
BMJ. 1992 May 9;304(6836):1199-200
pubmed: 1515786
Ocul Immunol Inflamm. 2019;27(1):15-22
pubmed: 28700247
Ocul Immunol Inflamm. 2018;26(8):1206-1211
pubmed: 28910560
Ocul Immunol Inflamm. 2021 Aug 18;29(6):1154-1163
pubmed: 32286112
Am J Ophthalmol. 2017 Nov;183:71-80
pubmed: 28887113
Retina. 2011 Jan;31(1):111-8
pubmed: 20856170
Br J Ophthalmol. 2007 Mar;91(3):335-9
pubmed: 17050581
Ann Rheum Dis. 2012 Apr;71(4):563-6
pubmed: 22084392
Invest Ophthalmol Vis Sci. 2008 Jul;49(7):3058-64
pubmed: 18579762
Arthritis Res Ther. 2010;12(3):R80
pubmed: 20459787
Rheumatology (Oxford). 2018 Dec 1;57(12):2200-2212
pubmed: 30107448
Retina. 2019 Aug;39(8):1607-1612
pubmed: 29689026
Arch Dermatol Res. 2010 Apr;302(3):155-68
pubmed: 20012749
Eye (Lond). 2014 Sep;28(9):1100-6
pubmed: 24946845
Semin Arthritis Rheum. 2004 Apr;33(5):320-35
pubmed: 15079763
Acta Ophthalmol Scand. 1997 Dec;75(6):720-2
pubmed: 9527339
Ocul Immunol Inflamm. 2020 May 18;28(4):589-600
pubmed: 31560572
Ophthalmology. 2018 Dec;125(12):1977-1983
pubmed: 30458922
Ocul Immunol Inflamm. 2019;27(8):1232-1234
pubmed: 31268748
J Clin Med. 2020 Nov 08;9(11):
pubmed: 33171664
Dev Ophthalmol. 2012;51:63-78
pubmed: 22517205
Transplant Proc. 1988 Jun;20(3 Suppl 4):136-43
pubmed: 3381269
Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1564-1568
pubmed: 32407246
Ocul Immunol Inflamm. 2013 Apr;21(2):160-2
pubmed: 23252659
Ocul Immunol Inflamm. 2007 Mar-Apr;15(2):63-70
pubmed: 17558830
Pediatr Rheumatol Online J. 2016 Feb 18;14(1):10
pubmed: 26887984
Autoimmun Rev. 2018 Jun;17(6):567-575
pubmed: 29631062
N Engl J Med. 1999 Oct 21;341(17):1284-91
pubmed: 10528040
Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):8
pubmed: 33666648
Br J Ophthalmol. 1992 Apr;76(4):241-3
pubmed: 1390495
Am J Ophthalmol. 2015 Mar;159(3):475-81.e1
pubmed: 25461299
Retina. 2016 Dec;36(12):2399-2408
pubmed: 27870802
Rheumatol Adv Pract. 2017 Jul 11;1(1):rkx004
pubmed: 31431944
Ocul Immunol Inflamm. 2019;27(1):34-39
pubmed: 29099660
Int J Rheum Dis. 2010 Aug;13(3):246-52
pubmed: 20704622
Ocul Immunol Inflamm. 2016 Oct;24(5):599-602
pubmed: 25760915
Expert Rev Clin Immunol. 2017 Jan;13(1):57-65
pubmed: 27351485
Ophthalmology. 2010 Aug;117(8):1612-6
pubmed: 20378179
J Rheumatol. 2015 Oct;42(10):1906-13
pubmed: 26276966
Front Immunol. 2019 May 14;10:1085
pubmed: 31139195
Graefes Arch Clin Exp Ophthalmol. 2008 Aug;246(8):1169-77
pubmed: 18504599
Rheumatology (Oxford). 2007 Oct;46(10):1570-3
pubmed: 17702770
Sci Rep. 2020 Dec 17;10(1):22227
pubmed: 33335139
Lancet. 2016 Sep 17;388(10050):1183-92
pubmed: 27542302
Ophthalmology. 2018 Sep;125(9):1444-1451
pubmed: 29602570
Am J Ophthalmol. 2012 Sep;154(3):534-541.e1
pubmed: 22789563
Drug Dev Res. 2015 Dec;76(8):419-27
pubmed: 26482111
Ocul Immunol Inflamm. 2013 Oct;21(5):337-50
pubmed: 23730816
Br J Ophthalmol. 1998 May;82(5):488-94
pubmed: 9713053
Front Immunol. 2021 Feb 04;11:626792
pubmed: 33613571
Neurol Neuroimmunol Neuroinflamm. 2022 Jan 26;9(2):
pubmed: 35082168
Immunotherapy. 2015;7(4):353-61
pubmed: 25917627
Expert Opin Emerg Drugs. 2020 Dec;25(4):531-547
pubmed: 33147420
Ann Rheum Dis. 2015 Jun;74(6):1138-44
pubmed: 25269831
Sci Rep. 2019 Jun 13;9(1):8612
pubmed: 31197217
J Ophthalmic Inflamm Infect. 2012 Dec;2(4):231-3
pubmed: 22581347
Retina. 2018 Apr;38(4):828-840
pubmed: 28272284
Immunol Invest. 2017 May;46(4):419-432
pubmed: 28388249
Arthritis Rheum. 2003 Jul;48(7):2025-35
pubmed: 12847697
Exp Eye Res. 2020 Jan;190:107853
pubmed: 31669406
Am J Ophthalmol. 2022 Jun;238:173-180
pubmed: 35172172
Surv Ophthalmol. 2005 Jul-Aug;50(4):297-350
pubmed: 15967189
J Autoimmun. 2015 Aug;62:67-74
pubmed: 26162757
Arthritis Rheum. 2010 Sep;62(9):2796-805
pubmed: 20518075
Graefes Arch Clin Exp Ophthalmol. 2009 Aug;247(8):1119-25
pubmed: 19296122
Lancet. 1989 May 20;1(8647):1093-6
pubmed: 2566048
Rheumatology (Oxford). 2011 Aug;50(8):1445-52
pubmed: 21427177
Clin Rheumatol. 2015 Jul;34(7):1293-301
pubmed: 24305945
Ophthalmology. 2013 Apr;120(4):777-87
pubmed: 23290985
Orphanet J Rare Dis. 2021 Feb 24;16(Suppl 1):352
pubmed: 33622338
J Rheumatol. 1994 Dec;21(12):2301-6
pubmed: 7699633
Clin Exp Rheumatol. 2022 Sep;40(8):1575-1583
pubmed: 36106545
Rev Med Interne. 2002 Nov;23 Suppl 4:495s-499s
pubmed: 12481405
Int J Retina Vitreous. 2021 Aug 28;7(1):48
pubmed: 34454608
N Engl J Med. 2001 Oct 11;345(15):1098-104
pubmed: 11596589
Am J Ophthalmol. 2004 Sep;138(3):373-80
pubmed: 15364218
J Korean Med Sci. 2020 Jul 27;35(29):e213
pubmed: 32715666
Int J Retina Vitreous. 2018 Apr 16;4:15
pubmed: 29692926
Clin Rheumatol. 2016 May;35(5):1281-6
pubmed: 26156661
Arthritis Rheumatol. 2019 Dec;71(12):2081-2089
pubmed: 31237427
J Ocul Pharmacol Ther. 2008 Dec;24(6):613-4; author reply 614
pubmed: 19049264
Ocul Immunol Inflamm. 2020 Nov 16;28(8):1166-1170
pubmed: 31411926
Rheumatology (Oxford). 2010 Nov;49(11):2217-9
pubmed: 20837498
Arch Ophthalmol. 1970 Oct;84(4):451-2
pubmed: 5492449
Acta Dermatovenerol Alp Pannonica Adriat. 2018 Dec;27(4):175-177
pubmed: 30564829
Rheumatology (Oxford). 2018 May 1;57(5):856-864
pubmed: 29471416
Ocul Immunol Inflamm. 2014 Feb;22(1):64-76
pubmed: 24377434
Ocul Immunol Inflamm. 2012 Oct;20(5):324-35
pubmed: 23030353
Eur Cytokine Netw. 2019 Mar 1;30(1):15-22
pubmed: 31122907
Transplant Proc. 2004 Mar;36(2 Suppl):372S-377S
pubmed: 15041371
Expert Opin Pharmacother. 2017 Sep;18(13):1311-1323
pubmed: 28750572
Int Ophthalmol Clin. 2012 Fall;52(4):183-90
pubmed: 22954940
Trans Am Ophthalmol Soc. 1979;77:225-79
pubmed: 397657
Am J Ophthalmol. 2022 Mar;235:336-338
pubmed: 34715076
Immunol Med. 2021 Jun;44(2):86-97
pubmed: 32726184
N Engl J Med. 2016 Sep 8;375(10):932-43
pubmed: 27602665
Front Immunol. 2020 Mar 10;11:358
pubmed: 32210963
Arch Rheumatol. 2018 Jan 31;33(3):352-357
pubmed: 30632534
Autoimmun Rev. 2010 Feb;9(4):241-5
pubmed: 19879978
Ocul Immunol Inflamm. 2012 Dec;20(6):423-8
pubmed: 23163330
Front Pharmacol. 2020 Jun 24;11:941
pubmed: 32670062
Am J Ophthalmol. 2008 Dec;146(6):837-44.e1
pubmed: 19027420
Am J Ophthalmol Case Rep. 2018 Dec 04;13:53-55
pubmed: 30582071
J Autoimmun. 2020 Sep;113:102481
pubmed: 32586650
Ann Rheum Dis. 2020 Aug;79(8):1098-1104
pubmed: 32381569
Lancet. 1994 Jun 4;343(8910):1428
pubmed: 7910903
Semin Arthritis Rheum. 2011 Aug;41(1):61-70
pubmed: 21168186
Ocul Immunol Inflamm. 2016 Jun;24(3):319-26
pubmed: 25549063
Ophthalmology. 2020 Oct;127(10):1431-1433
pubmed: 32423769
J Ophthalmol. 2017;2017:2180723
pubmed: 28596917
Ocul Immunol Inflamm. 2017 Feb;25(1):76-84
pubmed: 27541620
Ophthalmology. 2011 Sep;118(9):1892.e3-4
pubmed: 21889663
Ocul Immunol Inflamm. 2018;26(7):1023-1033
pubmed: 29370572
Int J Rheum Dis. 2013 Oct;16(5):568-77
pubmed: 24164845
Ocul Immunol Inflamm. 2010 Jun;18(3):226-32
pubmed: 20482404
Ocul Immunol Inflamm. 2000 Dec;8(4):293-301
pubmed: 11262659
Graefes Arch Clin Exp Ophthalmol. 2008 Jun;246(6):907-11
pubmed: 18414888
Arthritis Rheum. 2009 May 15;61(5):600-4
pubmed: 19405011
Int Ophthalmol. 2019 Oct;39(10):2213-2221
pubmed: 30875015
PLoS One. 2022 Jan 21;17(1):e0254972
pubmed: 35061677
Ophthalmology. 2015 May;122(5):939-48
pubmed: 25638011
Arch Dermatol. 2002 Apr;138(4):467-71
pubmed: 11939808
Sci Transl Med. 2010 Oct 6;2(52):52ra72
pubmed: 20926833
Rheumatology (Oxford). 2003 Dec;42(12):1539-44
pubmed: 12949252
Ophthalmology. 2022 May;129(5):520-529
pubmed: 34793830
J Control Release. 2021 May 10;333:283-297
pubmed: 33798665
J Eur Acad Dermatol Venereol. 2014 Mar;28(3):338-47
pubmed: 23441863
Ocul Immunol Inflamm. 2022 Jan 02;30(1):223-230
pubmed: 32815752
Rheumatology (Oxford). 2011 Mar;50(3):593-7
pubmed: 21097877
Turk J Ophthalmol. 2017 Oct;47(5):261-266
pubmed: 29109894