Impact of Smoking, Body Weight, Diabetes, Hypertension and Kidney Dysfunction on Survival in Pancreatic Cancer Patients-A Single Center Analysis of 2323 Patients within the Last Decade.
body mass index
diabetes
hypertension
insulin-therapy
kidney dysfunction
pancreatic cancer
pancreatic enzyme replacement therapy
smoking
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
25 May 2023
25 May 2023
Historique:
received:
13
03
2023
revised:
24
04
2023
accepted:
17
05
2023
medline:
10
6
2023
pubmed:
10
6
2023
entrez:
10
6
2023
Statut:
epublish
Résumé
In addition to being risk factors for pancreatic cancer, parameters such as smoking, diabetes, or obesity might also act as potential prognostic factors for the survival of patients initially diagnosed with pancreatic cancer. By implementing one of the largest retrospective study cohorts of 2323 pancreatic adenocarcinoma (PDAC) patients treated at a single high-volume center, potential prognostic factors for survival were evaluated on the basis of 863 cases. Since parameters such as smoking, obesity, diabetes, and hypertension can cause severe chronic kidney dysfunction, the glomerular filtration rate was also considered. In the univariate analyses, albumin (
Identifiants
pubmed: 37297851
pii: jcm12113656
doi: 10.3390/jcm12113656
pmc: PMC10253757
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Berliner Krebsgesellschaft
ID : PEFF202104
Références
JAMA Oncol. 2022 Nov 1;8(11):1571-1578
pubmed: 36048453
Pancreas. 2018 Sep;47(8):937-945
pubmed: 30113428
Cancer Res. 2017 Aug 15;77(16):4460-4471
pubmed: 28652247
Ann Oncol. 2008 May;19(5):996-1002
pubmed: 18212091
Pancreas. 2011 Aug;40(6):931-7
pubmed: 21747317
BMC Cancer. 2021 Dec 9;21(1):1318
pubmed: 34886801
J Clin Oncol. 2017 Jun 1;35(16):1822-1828
pubmed: 28358654
Pancreas. 2014 Jan;43(1):47-52
pubmed: 24177141
Int J Cancer. 2010 Nov 15;127(10):2412-9
pubmed: 20143395
Obes Facts. 2020;13(5):514-527
pubmed: 33075798
PLoS One. 2016 Nov 4;11(11):e0166008
pubmed: 27814399
Front Endocrinol (Lausanne). 2022 Jun 23;13:904001
pubmed: 35813613
Int Stat Rev. 2010 Apr;78(1):40-64
pubmed: 21743766
Int J Clin Oncol. 2001 Feb;6(1):50-4
pubmed: 11706528
JAMA. 2021 Sep 7;326(9):851-862
pubmed: 34547082
BMC Cancer. 2014 Sep 29;14:728
pubmed: 25266049
Nutrients. 2020 May 26;12(6):
pubmed: 32466362
Pancreas. 2019 Sep;48(8):985-995
pubmed: 31425484
Int J Clin Oncol. 2020 Sep;25(9):1587-1595
pubmed: 32514878
J Gastrointest Surg. 2018 Aug;22(8):1376-1384
pubmed: 29623673
Cancers (Basel). 2022 Jun 26;14(13):
pubmed: 35804906
BMJ. 2019 Jan 30;364:k4597
pubmed: 30700442
Chin Clin Oncol. 2013 Sep;2(3):26
pubmed: 25841682
JAMA. 2009 Jun 24;301(24):2553-62
pubmed: 19549972
Gastroenterology. 2021 Feb;160(3):744-754
pubmed: 33058868
Sci Rep. 2017 Aug 29;7(1):9572
pubmed: 28851896
PLoS Med. 2014 Oct 14;11(10):e1001744
pubmed: 25314315
Life (Basel). 2022 Oct 28;12(11):
pubmed: 36362879
Sci Rep. 2020 Oct 2;10(1):16425
pubmed: 33009477
Cancer. 2013 Jan 15;119(2):404-10
pubmed: 23292900
BMC Cancer. 2018 May 5;18(1):534
pubmed: 29728096
Am J Epidemiol. 2009 Aug 15;170(4):403-13
pubmed: 19561064
Sci Rep. 2015 Nov 24;5:17102
pubmed: 26598798
Ann Intern Med. 2009 May 5;150(9):604-12
pubmed: 19414839
Expert Rev Gastroenterol Hepatol. 2022 Jun;16(6):547-553
pubmed: 35686669
J Clin Oncol. 2006 Nov 1;24(31):5017-24
pubmed: 17075121
Am J Gastroenterol. 2014 Sep;109(9):1484-92
pubmed: 25070053
Cancer. 2020 Jan 1;126(9):1979-1986
pubmed: 32012239
Oxid Med Cell Longev. 2016;2016:5190314
pubmed: 27433288
Front Oncol. 2021 Sep 09;11:688889
pubmed: 34568019
World J Surg Oncol. 2022 Jul 1;20(1):221
pubmed: 35773692
Cancer Causes Control. 2020 Aug;31(8):767-776
pubmed: 32462559