Flavones: The Apoptosis in Prostate Cancer of Three Flavones Selected as Therapeutic Candidate Models.
apoptosis
cancer cell death
flavones
flavonoids
prostate cancer
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
25 May 2023
25 May 2023
Historique:
received:
04
04
2023
revised:
01
05
2023
accepted:
22
05
2023
medline:
12
6
2023
pubmed:
10
6
2023
entrez:
10
6
2023
Statut:
epublish
Résumé
Cancer is a widespread but dangerous disease that can strike anyone and is the second 1leading cause of death worldwide. Prostate cancer, in particular, is a prevalent cancer that occurs in men, and much research is being done on its treatment. Although chemical drugs are effective, they have various side effects, and accordingly, anticancer drugs using natural products are emerging. To date, many natural candidates have been discovered, and new drugs are being developed as drugs to treat prostate cancer. Representative candidate compounds that have been studied to be effective in prostate cancer include apigenin, acacetin and tangeretin of the flavone family among flavonoids. In this review, we look at the effects of these three flavones on prostate cancer cells via apoptosis in vitro and in vivo. Furthermore, in addition to the existing drugs, we suggest the three flavones and their effectiveness as natural anticancer agents, a treatment model for prostate cancer.
Identifiants
pubmed: 37298192
pii: ijms24119240
doi: 10.3390/ijms24119240
pmc: PMC10252627
pii:
doi:
Substances chimiques
Flavones
0
Flavonoids
0
Apigenin
7V515PI7F6
Antineoplastic Agents
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Cancer Res. 2006 Mar 1;66(5):2815-25
pubmed: 16510604
Lancet Oncol. 2010 Nov;11(11):1066-73
pubmed: 20933466
Cancer Res. 2003 Oct 15;63(20):6795-801
pubmed: 14583476
Zhongguo Zhong Yao Za Zhi. 2004 Sep;29(9):863-4
pubmed: 15575204
EMBO J. 1997 Nov 3;16(21):6355-63
pubmed: 9351818
Free Radic Biol Med. 1997;22(5):749-60
pubmed: 9119242
Cancer Discov. 2013 Aug;3(8):849-61
pubmed: 23811619
Arch Biochem Biophys. 2002 Mar 1;399(1):103-8
pubmed: 11883909
Nutrients. 2020 Feb 12;12(2):
pubmed: 32059369
World J Oncol. 2019 Apr;10(2):63-89
pubmed: 31068988
Br J Pharmacol. 2006 Feb;147 Suppl 2:S144-52
pubmed: 16465179
Food Chem Toxicol. 2020 Nov;145:111708
pubmed: 32866514
Int J Mol Med. 2014 Feb;33(2):317-24
pubmed: 24285354
Cancers (Basel). 2018 Dec 28;11(1):
pubmed: 30597838
Cancer Res. 2012 Mar 15;72(6):1494-503
pubmed: 22266222
Mol Cancer Res. 2003 Dec;1(14):1036-47
pubmed: 14707287
Nature. 2007 Mar 15;446(7133):316-9
pubmed: 17287723
Endocr Rev. 2004 Apr;25(2):276-308
pubmed: 15082523
Methods Enzymol. 1990;186:343-55
pubmed: 2172711
Cancer Epidemiol Biomarkers Prev. 1999 Apr;8(4 Pt 1):277-82
pubmed: 10207628
Food Funct. 2013 Jun;4(6):944-9
pubmed: 23673480
Nat Rev Urol. 2010 Aug;7(8):442-53
pubmed: 20647991
Apoptosis. 2014 May;19(5):883-94
pubmed: 24563225
Food Chem Toxicol. 1999 Sep-Oct;37(9-10):937-42
pubmed: 10541448
PLoS One. 2011;6(5):e19494
pubmed: 21603658
Nat Rev Clin Oncol. 2014 Jun;11(6):308-23
pubmed: 24840073
Cell. 1997 Nov 14;91(4):479-89
pubmed: 9390557
Eur J Cancer Prev. 2014 Mar;23(2):96-109
pubmed: 23872953
Oncologist. 2012;17(9):1171-9
pubmed: 22836449
Oncotarget. 2015 Oct 13;6(31):31216-32
pubmed: 26435478
World J Mens Health. 2019 Sep;37(3):288-295
pubmed: 30209899
Oncogene. 2006 Aug 7;25(34):4798-811
pubmed: 16892092
Drugs. 2018 Apr;78(6):699-705
pubmed: 29626324
Expert Opin Pharmacother. 2015 Apr;16(5):749-54
pubmed: 25687355
Nutrients. 2020 Aug 21;12(9):
pubmed: 32825564
Int J Cancer. 2021 Apr 5;:
pubmed: 33818764
Chem Biol Interact. 2020 Sep 25;329:109147
pubmed: 32738202
J Natl Cancer Inst. 2000 Dec 20;92(24):2018-23
pubmed: 11121464
J Med Genet. 2003 Mar;40(3):e21
pubmed: 12624150
Exp Oncol. 2010 Jul;32(2):66-70
pubmed: 20693964
Lancet. 2022 Jan 29;399(10323):447-460
pubmed: 34953525
Trends Cell Biol. 2013 Dec;23(12):620-33
pubmed: 23958396
Oncogene. 2013 Dec 5;32(49):5501-11
pubmed: 23752182
Clin Cancer Res. 2010 Apr 1;16(7):2115-21
pubmed: 20215531
Cancer Res. 2003 Jun 1;63(11):2905-12
pubmed: 12782597
Carcinogenesis. 2014 Feb;35(2):452-60
pubmed: 24067903
Nat Commun. 2018 Aug 28;9(1):3490
pubmed: 30154431
Science. 2000 May 12;288(5468):1053-8
pubmed: 10807576
J Natl Cancer Inst. 2001 Nov 21;93(22):1687-97
pubmed: 11717329
Pharmacol Res. 2020 Nov;161:105202
pubmed: 32942013
Adv Biochem Eng Biotechnol. 1998;62:75-105
pubmed: 9755641
J Cell Biochem. 2006 Jan 1;97(1):18-32
pubmed: 16216007
Cancer Metastasis Rev. 2001;20(3-4):225-43
pubmed: 12085964
Molecules. 2020 Jun 03;25(11):
pubmed: 32503228
Mol Cell. 2002 Mar;9(3):459-70
pubmed: 11931755
Clin Cancer Res. 2004 Jan 15;10(2):440-8
pubmed: 14760063
Int J Mol Sci. 2018 Feb 02;19(2):
pubmed: 29393886
N Engl J Med. 1998 Oct 8;339(15):1036-42
pubmed: 9761805
Rev Urol. 2008 Spring;10(2):111-9
pubmed: 18660852
Int J Radiat Oncol Biol Phys. 1998 Jan 1;40(1):17-25
pubmed: 9422553
Eur Urol. 1997;31(2):216-9
pubmed: 9076469
J Urol. 2010 Dec;184(6):2303-7
pubmed: 20952027
CMAJ. 1998 Oct 6;159(7):807-13
pubmed: 9805030
Clin Cancer Res. 2007 Dec 1;13(23):7003-11
pubmed: 18056176
Am J Clin Nutr. 2015 Jan;101(1):173-83
pubmed: 25527761
Nutrients. 2016 Aug 22;8(8):
pubmed: 27556486
Cells. 2021 Jan 19;10(1):
pubmed: 33478015
Curr Comput Aided Drug Des. 2011 Jun;7(2):146-57
pubmed: 21534921
J Urol. 2018 Nov;200(5):956-966
pubmed: 29730201
J Urol. 2011 Aug;186(2):465-9
pubmed: 21679996
J Urol. 2010 Jan;183(1):345-50
pubmed: 19914662
Food Chem. 2013 May 1;138(1):48-53
pubmed: 23265454
Semin Oncol Nurs. 2011 May;27(2):104-15
pubmed: 21514480
Prostate. 2011 Jul;71(10):1054-63
pubmed: 21557270
Am J Transl Res. 2009 Apr 20;1(3):235-48
pubmed: 19956434
Actas Urol Esp. 2011 May;35(5):282-8
pubmed: 21435741
Molecules. 2021 Oct 14;26(20):
pubmed: 34684783
Eur Urol. 2013 May;63(5):800-9
pubmed: 23219374
J Pharmacol Exp Ther. 1996 Jun;277(3):1237-46
pubmed: 8667184
J Urol. 1974 Jan;111(1):58-64
pubmed: 4813554
J Nutr Sci. 2016 Dec 29;5:e47
pubmed: 28620474
Best Pract Res Clin Endocrinol Metab. 2008 Apr;22(2):389-402
pubmed: 18471794
Front Oncol. 2019 Aug 28;9:801
pubmed: 31555580
BJU Int. 2004 May;93(8):1139-50
pubmed: 15142129
Cell Biosci. 2017 Oct 5;7:50
pubmed: 29034071
Oncogene. 2002 May 23;21(23):3727-38
pubmed: 12032841
Nat Prod Rep. 2010 Nov;27(11):1571-93
pubmed: 20877900
Eur Urol. 2011 Apr;59(4):572-83
pubmed: 21315502
Eur J Pharmacol. 1999 May 28;373(1):51-62
pubmed: 10408251
Iran Red Crescent Med J. 2013 Apr;15(4):279-84
pubmed: 24082997
Adv Nutr. 2017 May 15;8(3):423-435
pubmed: 28507008
Cancer Discov. 2022 Jan;12(1):31-46
pubmed: 35022204
Pharm Acta Helv. 2000 Mar;74(2-3):281-6
pubmed: 10812970
Prostate. 2005 Feb 1;62(2):165-86
pubmed: 15389801
Int J Antimicrob Agents. 2005 Nov;26(5):343-56
pubmed: 16323269
Sci Rep. 2017 May 16;7(1):1955
pubmed: 28512306
Life Sci. 2016 Oct 1;162:77-86
pubmed: 27569589
J Natl Cancer Inst. 2011 Jun 8;103(11):876-84
pubmed: 21586702
Oncol Lett. 2018 Jan;15(1):433-440
pubmed: 29375715
Eur Urol. 2016 Jul;70(1):106-119
pubmed: 26996659
Expert Rev Endocrinol Metab. 2011 May;6(3):483-493
pubmed: 22389648
J Minim Access Surg. 2005 Oct;1(4):196-201
pubmed: 21206663
Eur J Med Chem. 2017 Dec 15;142:213-228
pubmed: 28793973
Cancer. 2004 Nov 15;101(10 Suppl):2371-490
pubmed: 15495199
Clin Cancer Res. 2005 Jul 1;11(13):4653-7
pubmed: 16000557
Science. 2009 May 8;324(5928):787-90
pubmed: 19359544
Endocr Relat Cancer. 2010 Jan 29;17(1):R39-52
pubmed: 19926708
Cancer Treat Rev. 2004 Apr;30(2):193-204
pubmed: 15023437
Carcinogenesis. 2005 Apr;26(4):845-54
pubmed: 15637089
EPMA J. 2021 May 17;12(2):155-176
pubmed: 34025826