Antioxidant, Anti-Inflammatory, and Anti-Cancer Properties of Amygdalin Extracted from Three Cassava Varieties Cultivated in Benin.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
05 Jun 2023
Historique:
received: 05 05 2023
revised: 23 05 2023
accepted: 30 05 2023
medline: 12 6 2023
pubmed: 10 6 2023
entrez: 10 6 2023
Statut: epublish

Résumé

Given that cancer is a disease that is rampant in the world and especially in Africa, where the population has enormous difficulty treating it, plants are a safer and less expensive alternative. Cassava is a plant species valued in Benin because of its numerous medicinal and nutritional virtues. This study evaluated the biological activities of amygdalin from the organs of three cassava varieties most commonly produced in Benin (BEN, RB, and MJ). HPLC analysis was used to quantify amygdalin in cassava organs and derivatives. Phytochemical screening was performed to determine secondary metabolite groups. DPPH and FRAP methods were used to assess antioxidant activity. Cytotoxicity of the extracts was tested on

Identifiants

pubmed: 37299029
pii: molecules28114548
doi: 10.3390/molecules28114548
pmc: PMC10254302
pii:
doi:

Substances chimiques

Antioxidants 0
Plant Extracts 0
Amygdalin 214UUQ9N0H
Anti-Inflammatory Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

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Auteurs

Halfane Lehmane (H)

Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cell Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Cotonou 05 BP 1604, Benin.

Arnaud N Kohonou (AN)

Laboratory of Research in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou 01 BP 2009, Benin.

Atchadé Pascal Tchogou (AP)

Experimental and Clinical Biology Laboratory, National School of Applied Biosciences and Biotechnologies, National University of Science, Technology, Engineering and Mathematics (UNSTIM), Dassa-Zoumé 01 BP 1471, Benin.

Radiate Ba (R)

Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cell Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Cotonou 05 BP 1604, Benin.

Durand Dah-Nouvlessounon (D)

Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cell Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Cotonou 05 BP 1604, Benin.

Oscar Didagbé (O)

Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cell Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Cotonou 05 BP 1604, Benin.

Haziz Sina (H)

Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cell Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Cotonou 05 BP 1604, Benin.

Maximin Senou (M)

Experimental and Clinical Biology Laboratory, National School of Applied Biosciences and Biotechnologies, National University of Science, Technology, Engineering and Mathematics (UNSTIM), Dassa-Zoumé 01 BP 1471, Benin.

Adolphe Adjanohoun (A)

Institut National des Recherches Agricoles du Bénin, Cotonou 01 BP 884, Benin.

Lamine Baba-Moussa (L)

Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cell Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Cotonou 05 BP 1604, Benin.

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Classifications MeSH