The Impact of Vaccination Time on the Antibody Response to an Inactivated Vaccine against SARS-CoV-2 (IMPROVE-2): A Randomized Controlled Trial.
SARS-CoV-2
inactivated vaccine
neutralizing antibody
time of day
Journal
Advanced biology
ISSN: 2701-0198
Titre abrégé: Adv Biol (Weinh)
Pays: Germany
ID NLM: 101775319
Informations de publication
Date de publication:
11 2023
11 2023
Historique:
revised:
22
05
2023
received:
18
01
2023
medline:
22
11
2023
pubmed:
10
6
2023
entrez:
10
6
2023
Statut:
ppublish
Résumé
There is still controversy about whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination at different times of day will induce a stronger immune response. Therefore, a randomized controlled trial (ChiCTR2100045109) is conducted to investigate the impact of vaccination time on the antibody response to the inactivated vaccine against SARS-CoV-2 from April 15 to 28, 2021. Participants are randomly assigned in a 1:1 ratio to receive inactivated SARS-CoV-2 vaccine in the morning or afternoon. The primary endpoint is the change of neutralizing antibody between baseline and 28 days after the second dose. In total, 503 participants are randomized, and 469 participants (238 in the morning group and 231 in the afternoon group) complete the follow-up. There is no significant difference in the change of neutralizing antibody between baseline and 28 days after the second dose between the morning and afternoon groups (22.2 [13.2, 45.0] AU mL
Identifiants
pubmed: 37300345
doi: 10.1002/adbi.202300028
doi:
Substances chimiques
COVID-19 Vaccines
0
Antibodies, Neutralizing
0
Vaccines, Inactivated
0
Types de publication
Randomized Controlled Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2300028Subventions
Organisme : Talent Program of First Affiliated Hospital of Sun Yat-Sen University
ID : Y70311
Organisme : National Natural Science Foundation of China
ID : 82103035
Organisme : Science and Technology Planning Project of Guangzhou
ID : 2022342
Informations de copyright
© 2023 Wiley-VCH GmbH.
Références
J. Sadoff, M. L. Gars, G. Shukarev, D. Heerwegh, C. Truyers, A. M. de Groot, J. Stoop, S. Tete, W. Van Damme, I. Leroux-Roels, P. J. Berghmans, M. Kimmel, P. Van Damme, J. de Hoon, W. Smith, K. E. Stephenson, S. C. De Rosa, K. W. Cohen, M. J. Mcelrath, E. Cormier, G. Scheper, D. H. Barouch, J. Hendriks, F. Struyf, M. Douoguih, J. Van Hoof, H. Schuitemaker, N. Engl. J. Med. 2021, 384, 1824.
S. Xia, Y. Zhang, Y. Wang, H. Wang, Y. Yang, G. F. Gao, W. Tan, G. Wu, M. Xu, Z. Lou, W. Huang, W. Xu, B. Huang, H. Wang, W. Wang, W. Zhang, N. Li, Z. Xie, L. Ding, W. You, Y. Zhao, X. Yang, Y. Liu, Q. Wang, L. Huang, Y. Yang, G. Xu, B. Luo, W. Wang, P. Liu, et al., Lancet Infect. Dis. 2021, 21, 39.
S. Xia, K. Duan, Y. Zhang, D. Zhao, H. Zhang, Z. Xie, X. Li, C. Peng, Y. Zhang, W. Zhang, Y. Yang, W. Chen, X. Gao, W. You, X. Wang, Z. Wang, Z. Shi, Y. Wang, X. Yang, L. Zhang, L. Huang, Q. Wang, J. Lu, Y. Yang, J. Guo, W. Zhou, X. Wan, C. Wu, W. Wang, S. Huang, et al., J. Am. Med. Assoc. 2020, 324, 951.
M. Jeyanathan, S. Afkhami, F. Smaill, M. S. Miller, B. D. Lichty, Z. Xing, Nat. Rev. Immunol. 2020, 20, 615.
C. Scheiermann, J. Gibbs, L. Ince, A. Loudon, Nat. Rev. Immunol. 2018, 18, 423.
R. Allada, J. Bass, N. Engl. J. Med. 2021, 384, 550.
J. E. Long, M. T. Drayson, A. E. Taylor, K. M. Toellner, J. M. Lord, A. C. Phillips, Vaccine 2016, 34, 2679.
Y. Liu, H. Zhang, G. Yuan, M. Yao, B. Li, J. Chen, Y. Fan, R. Mo, F. Lai, X. Chen, M. Li, B. Chen, J. M. Lord, S. Peng, K. Cheng, H. Xiao, Immun. Ageing 2022, 19, 46.
R. D. Feigin, R. F. Jaeger, R. W. Mckinney, A. C. Alevizatos, Am. J. Trop. Med. Hyg. 1967, 16, 769.
A. C. Phillips, S. Gallagher, D. Carroll, M. Drayson, Psychophysiology 2008, 45, 663.
H. Zhang, Y. Liu, D. Liu, Q. Zeng, L. Li, Q. Zhou, M. Li, J. Mei, N. Yang, S. Mo, Q. Liu, M. Liu, S. Peng, H. Xiao, Cell Res. 2021, 31, 1215.
W. Wang, P. Balfe, D. W. Eyre, S. F. Lumley, D. O'Donnell, F. Warren, D. W. Crook, K. Jeffery, P. C. Matthews, E. B. Klerman, J. A. Mckeating, J. Biol. Rhythms 2021, 606907789.
Y. Yamanaka, I. Yokota, A. Yasumoto, E. Morishita, H. Horiuchi, J. Biol. Rhythms 2022, 37, 700.
E. E. Fortier, J. Rooney, H. Dardente, M. P. Hardy, N. Labrecque, N. Cermakian, J. Immunol. 2011, 187, 6291.
C. C. Nobis, L. G. Dubeau, L. Kervezee, D. S. D. Maurice, N. Labrecque, N. Cermakian, Proc. Natl. Acad. Sci. USA 2019, 116, 20077.
L. de Bree, V. P. Mourits, V. A. Koeken, S. J. Moorlag, R. Janssen, L. Folkman, D. Barreca, T. Krausgruber, V. Fife-Gernedl, B. Novakovic, R. J. Arts, H. Dijkstra, H. Lemmers, C. Bock, L. A. Joosten, R. van Crevel, C. S. Benn, M. G. Netea, J. Clin. Invest. 2020, 130, 5603.
O. Karabay, A. Temel, A. G. Koker, M. Tokel, M. Ceyhan, E. Kocoglu, Vaccine 2008, 26, 1143.
M. P. Cervantes-Silva, R. G. Carroll, M. M. Wilk, D. Moreira, C. A. Payet, J. R. O'Siorain, S. L. Cox, L. E. Fagan, P. A. Klavina, Y. He, T. Drewinski, A. McGinley, S. M. Buel, G. A. Timmons, J. O. Early, R. Preston, J. M. Hurley, D. K. Finlay, I. Schoen, S. F. Javier, K. Mills, A. M. Curtis, Nat. Commun. 2022, 13, 7217.
L. M. Ince, C. Barnoud, L. K. Lutes, R. Pick, C. Wang, F. Sinturel, C. S. Chen, A. de Juan, J. Weber, S. J. Holtkamp, S. M. Hergenhan, J. Geddes-McAlister, S. Ebner, P. Fontannaz, B. Meyer, M. Vono, S. Jemelin, C. Dibner, C. A. Siegrist, F. Meissner, F. Graw, C. Scheiermann, Nat. Commun. 2023, 14, 476.
Q. He, Q. Mao, X. Peng, Z. He, S. Lu, J. Zhang, F. Gao, L. Bian, C. An, W. Yu, F. Yang, Y. Zhou, Y. Yang, Y. Li, Y. Yuan, X. Yan, J. Yang, X. Wu, W. Huang, C. Li, J. Wang, Z. Liang, M. Xu, Signal Transduct. Target Ther. 2022, 7, 69.
R. J. Engler, M. R. Nelson, M. M. Klote, M. J. Vanraden, C. Y. Huang, N. J. Cox, A. Klimov, W. A. Keitel, K. L. Nichol, W. W. Carr, J. J. Treanor, Arch. Intern. Med. 2008, 168, 2405.
S. L. Klein, I. Marriott, E. N. Fish, Trans. Roy. Soc. Trop. Med. Hyg. 2015, 109, 9.
K. L. Flanagan, A. L. Fink, M. Plebanski, S. L. Klein, Annu. Rev. Cell Dev. Biol. 2017, 33, 577.
E. Terpos, I. P. Trougakos, F. Apostolakou, I. Charitaki, A. D. Sklirou, N. Mavrianou, E. D. Papanagnou, C. I. Liacos, S. Gumeni, G. Rentziou, E. Korompoki, I. Papassotiriou, M. A. Dimopoulos, Am. J. Hematol. 2021, 96, E257.
E. Montecino-Rodriguez, B. Berent-Maoz, K. Dorshkind, J. Clin. Invest. 2013, 123, 958.
L. Muller, S. Di Benedetto, G. Pawelec, Subcell Biochem. 2019, 91, 21.
J. L. Heaney, A. C. Phillips, D. Carroll, Int. J. Psychophysiol. 2010, 78, 201.
T. Roenneberg, A. Wirz-Justice, M. Merrow, J. Biol. Rhythms 2003, 18, 80.
K. Papantoniou, G. Castano-Vinyals, A. Espinosa, N. Aragones, B. Perez-Gomez, E. Ardanaz, J. M. Altzibar, V. M. Sanchez, I. Gomez-Acebo, J. Llorca, D. Munoz, A. Tardon, R. Peiro, R. Marcos-Gragera, M. Pollan, M. Kogevinas, Eur. J. Epidemiol. 2016, 31, 867.