Identification of a unique intervillous cellular signature in chronic histiocytic intervillositis.
Journal
Placenta
ISSN: 1532-3102
Titre abrégé: Placenta
Pays: Netherlands
ID NLM: 8006349
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
received:
19
02
2023
revised:
15
04
2023
accepted:
13
05
2023
medline:
4
8
2023
pubmed:
11
6
2023
entrez:
10
6
2023
Statut:
ppublish
Résumé
Chronic histiocytic intervillositis (CHI) is a rare histopathological lesion in the placenta characterized by an infiltrate of CD68 We used imaging mass cytometry to achieve in-depth visualization of the intervillous maternal immune cells and investigated their spatial orientation in situ in relation to the fetal syncytiotrophoblast. We found three phenotypically distinct CD68 The current results provide novel insight into the phenotype of CD68
Identifiants
pubmed: 37300938
pii: S0143-4004(23)00114-5
doi: 10.1016/j.placenta.2023.05.007
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
34-42Subventions
Organisme : Medical Research Council
ID : MR/V028731/1
Pays : United Kingdom
Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors do not have a conflict of interest.