Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
11 06 2023
Historique:
received: 04 02 2023
accepted: 08 06 2023
medline: 13 6 2023
pubmed: 12 6 2023
entrez: 11 6 2023
Statut: epublish

Résumé

Cross-sectional relationships between nocturia and sleep problems have been well evaluated but the risk association for each incidence is scarcely reported. This analysis included 8076 participants of the Nagahama study in Japan (median age 57, 31.0% male) and associations between nocturia and self-reported, sleep-related problems (poor sleep) were evaluated cross-sectionally. Causal effects on each new-onset case were analyzed longitudinally after 5 years. Three models were applied: univariable analysis, adjustment for basic variables (i.e., demographic and lifestyle variables) and full adjustment for basic and clinical variables. The overall prevalences of poor sleep and nocturia were 18.6% and 15.5%, while poor sleep was positively associated with nocturia (OR = 1.85, p < 0.001) and vice versa (OR = 1.90, p < 0.001). Among 6579 good sleep participants, 18.5% developed poor sleep. Baseline nocturia was positively associated with this incident poor sleep (OR = 1.49, p < 0.001, full adjustment). Among 6824 non-nocturia participants, the nocturia incidence was 11.3%. Baseline poor sleep was positively associated with this incident nocturia (OR = 1.26, p = 0.026); such associations were significant only in women (OR = 1.44, p = 0.004) and under-50-year-old groups (OR = 2.82, p < 0.001), after full adjustment. Nocturia and poor sleep associate with each other. Baseline nocturia can induce new-onset poor sleep while baseline poor sleep may induce new-onset nocturia only in women.

Identifiants

pubmed: 37302997
doi: 10.1038/s41598-023-36707-y
pii: 10.1038/s41598-023-36707-y
pmc: PMC10258194
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9495

Informations de copyright

© 2023. The Author(s).

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Auteurs

Hiromitsu Negoro (H)

Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. hnegoro@md.tsukuba.ac.jp.
Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan. hnegoro@md.tsukuba.ac.jp.

Kazuya Setoh (K)

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Graduate School of Public Health, Shizuoka Graduate University of Public Health, Aoi-Ku, Shizuoka, Japan.

Arinobu Fukunaga (A)

Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Takahisa Kawaguchi (T)

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Satoshi Funada (S)

Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Takayuki Yoshino (T)

Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Koji Yoshimura (K)

Department of Urology, Shizuoka General Hospital, Shizuoka, Japan.

Bryan J Mathis (BJ)

International Medical Center, University of Tsukuba Affiliated Hospital, Ibaraki, Japan.

Yasuharu Tabara (Y)

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Graduate School of Public Health, Shizuoka Graduate University of Public Health, Aoi-Ku, Shizuoka, Japan.

Fumihiko Matsuda (F)

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Osamu Ogawa (O)

Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Takashi Kobayashi (T)

Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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