Anxiety and depression in women with asthma prior to fertility treatment.
Anxiety
Asthma
Depression
Fertility treatment
Infertility
Journal
European clinical respiratory journal
ISSN: 2001-8525
Titre abrégé: Eur Clin Respir J
Pays: United States
ID NLM: 101662134
Informations de publication
Date de publication:
2023
2023
Historique:
medline:
14
6
2023
pubmed:
14
6
2023
entrez:
14
6
2023
Statut:
epublish
Résumé
We investigate symptoms of anxiety and depression among women with asthma prior to fertility treatment. This is a cross-sectional study of women screened for eligibility to the PRO-ART study (RCT of omalizumab versus placebo in asthmatic women undergoing fertility treatment (NCT03727971)). All participants were scheduled for in vitro fertilization (IVF) treatment at four public fertility clinics in Denmark. Data on demographics and asthma control (ACQ-5) were obtained. Symptoms of anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS-A and D, respectively) and defined as being present on both subscales if a score >7 was obtained. Spirometry, diagnostic asthma test, and measurement of fractional exhaled nitric oxide (FeNO) were conducted. A total of 109 women with asthma were included (mean age 31.8 ± 4.6 and BMI 25.5 ± 4.6). Most women had male factor infertility (36.4%) or unexplained infertility (35.5%). Twenty-two percent of the patients reported uncontrolled asthma (ACQ-5 score > 1.5). The mean HADS-A and HADS-D scores were 6.0 ± 3.8 (95% CI 5.3-6.7) and 2.5 ± 2.2 (95% CI 2.1-3.0), respectively. Thirty (28.0%) women reported anxiety symptoms, and four (3.7%) had concomitant depressive symptoms. Uncontrolled asthma was significantly associated with both depressive ( More than 25% of women with asthma prior to fertility treatment had self-reported symptoms of anxiety, and just below 5% had self-reported depressive symptoms, possibly related to uncontrolled asthma.
Identifiants
pubmed: 37313367
doi: 10.1080/20018525.2023.2221376
pii: 2221376
pmc: PMC10259298
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2221376Informations de copyright
© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
Déclaration de conflit d'intérêts
The clinical trial PRO-ART is financed by a grant from Novartis, and the study drug omalizumab is provided by Norvartis (CIGE025ADK01T PROART). CSU has outside the submitted work received personal fees from AZ, TEVA, Novartis, Pfizer, GSK, Takeda, BI, Berlin Chemie, Sanofi, Covis Pharma and Orion Pharma. The authors (EYH, AVH, CT, NLF, HSN & VB) declare that they also have no conflict of interests in relation to this manuscript.
Références
Clin Transl Allergy. 2013 Feb 01;3(1):3
pubmed: 23369181
Eur Respir J. 2017 May 1;49(5):
pubmed: 28461290
Respir Med. 2006 Apr;100(4):616-21
pubmed: 16226443
Eur Respir Rev. 2020 Jun 3;29(156):
pubmed: 32499305
Ann Allergy Asthma Immunol. 2015 Nov;115(5):408-14
pubmed: 26392047
BMC Womens Health. 2017 Jul 24;17(1):48
pubmed: 28738833
Eur Respir J. 1999 Oct;14(4):902-7
pubmed: 10573240
Depress Anxiety. 2012 Dec;29(12):1065-71
pubmed: 23184657
Ann Epidemiol. 2003 May;13(5):317-24
pubmed: 12821270
Eur Respir J. 2014 Apr;43(4):1077-85
pubmed: 24232708
Otolaryngol Head Neck Surg. 2019 Oct;161(4):551-560
pubmed: 31159641
J Psychosom Res. 1997 Jan;42(1):17-41
pubmed: 9055211
Neurosci Lett. 2017 Aug 24;656:15-21
pubmed: 28716529
J Clin Med. 2018 Nov 23;7(12):
pubmed: 30477110
Ann Agric Environ Med. 2013;20(3):504-8
pubmed: 24069855
J Asthma. 2018 Dec;55(12):1271-1277
pubmed: 29336633
Eur Respir J. 2019 Dec 19;54(6):
pubmed: 31619474
Int J Gynaecol Obstet. 2015 Sep;130(3):253-6
pubmed: 26100348
Monaldi Arch Chest Dis. 2019 Sep 10;89(3):
pubmed: 31505919
Am J Respir Crit Care Med. 2005 Apr 15;171(8):912-30
pubmed: 15817806
Respir Med. 2005 May;99(5):553-8
pubmed: 15823451
Respir Med. 2014 Nov;108(11):1594-600
pubmed: 25282543
Eur Respir J. 2019 Feb 14;53(2):
pubmed: 30464019
Hum Reprod. 2008 Sep;23(9):2056-63
pubmed: 18583334
J Psychosom Res. 2002 Feb;52(2):69-77
pubmed: 11832252
Hum Reprod. 2015 Apr;30(4):777-82
pubmed: 25662810
Neuropsychiatr Dis Treat. 2021 Feb 25;17:649-657
pubmed: 33658786
BMC Emerg Med. 2015 Oct 12;15:28
pubmed: 26459412
Eur Respir J. 2005 Aug;26(2):319-38
pubmed: 16055882
Acta Psychiatr Scand. 1983 Jun;67(6):361-70
pubmed: 6880820
J Asthma Allergy. 2022 Jan 05;15:13-23
pubmed: 35027831
Gynecol Endocrinol. 2019 Jun;35(6):485-489
pubmed: 30612477
Respir Med. 2010 Jan;104(1):22-8
pubmed: 19733042
Am J Respir Crit Care Med. 2011 Sep 1;184(5):602-15
pubmed: 21885636
Eur Respir J. 2016 Apr;47(4):1144-51
pubmed: 26869675
Psychol Med. 2021 Jan;51(1):11-20
pubmed: 33431086
Clin Respir J. 2021 Jul;15(7):741-752
pubmed: 33783133
J Asthma. 2013 May;50(4):383-9
pubmed: 23368420
Respir Med. 1990 Jan;84(1):37-42
pubmed: 2371419
BMJ Open. 2020 Nov 12;10(11):e037041
pubmed: 33184076
J Affect Disord. 2014 Sep;166:22-9
pubmed: 25012406
Respir Med. 2014 Feb;108(2):278-86
pubmed: 24361162
Respir Med. 2016 Nov;120:44-53
pubmed: 27817815
Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):758-65
pubmed: 9309990
J Asthma. 2017 Sep;54(7):706-713
pubmed: 28075198
Eur Respir J. 1993 Mar;6 Suppl 16:5-40
pubmed: 24576915