Pertuzumab Plus Trastuzumab in Patients With Lung Cancer With


Journal

JCO precision oncology
ISSN: 2473-4284
Titre abrégé: JCO Precis Oncol
Pays: United States
ID NLM: 101705370

Informations de publication

Date de publication:
06 2023
Historique:
medline: 16 6 2023
pubmed: 14 6 2023
entrez: 14 6 2023
Statut: ppublish

Résumé

The Targeted Agent and Profiling Utilization Registry Study is a pragmatic basket trial evaluating antitumor activity of commercially available targeted agents in patients with advanced cancers harboring potentially actionable genomic alterations. Data from a cohort of patients with lung cancer and Eligible patients had advanced lung cancer of any histology, no standard treatment options, measurable disease (RECIST v1.1), Eastern Cooperative Oncology Group performance status 0-2, adequate organ function, and tumors with Twenty-eight patients with lung cancer (27 non-small-cell, 1 small-cell) and Combination P + T showed evidence of antitumor activity in heavily pretreated patients with non-small-cell lung cancer and

Identifiants

pubmed: 37315265
doi: 10.1200/PO.23.00041
doi:

Substances chimiques

Antineoplastic Agents 0
ERBB2 protein, human EC 2.7.10.1
pertuzumab K16AIQ8CTM
Receptor, ErbB-2 EC 2.7.10.1
Trastuzumab P188ANX8CK

Banques de données

ClinicalTrials.gov
['NCT02693535']

Types de publication

Journal Article Pragmatic Clinical Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2300041

Auteurs

Apar K Ganti (AK)

University of Nebraska Medical Center and VA-NWIHCS, Omaha, NE.

Michael Rothe (M)

American Society of Clinical Oncology, Alexandria, VA.

Pam K Mangat (PK)

American Society of Clinical Oncology, Alexandria, VA.

Elizabeth Garrett-Mayer (E)

American Society of Clinical Oncology, Alexandria, VA.

Elie G Dib (EG)

Michigan Cancer Research Consortium, Ypsilanti, MI.

Herbert L Duvivier (HL)

Cancer Treatment Centers of America-Atlanta, part of City of Hope, Newnan, GA.

Eugene R Ahn (ER)

Cancer Treatment Centers of America-Chicago, part of City of Hope, Zion, IL.

Deepti Behl (D)

Sutter Sacramento Medical Center, Sacramento, CA.

Hossein Borghaei (H)

Fox Chase Cancer Center, Philadelphia, PA.

Ani S Balmanoukian (AS)

The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate, Los Angeles, CA.

Anu Gaba (A)

Sanford Health, Fargo, ND.

Rui Li (R)

Providence Portland Medical Center, Providence Cancer Institute, Portland, OR.

Kwabena Osei-Boateng (K)

Levine Cancer Institute, Atrium Health, Charlotte, NC.

Ramya Thota (R)

Intermountain Healthcare, Murray, UT.

Gina N Grantham (GN)

American Society of Clinical Oncology, Alexandria, VA.

Abigail Gregory (A)

American Society of Clinical Oncology, Alexandria, VA.

Susan Halabi (S)

Duke University Medical Center, Durham, NC.

Richard L Schilsky (RL)

American Society of Clinical Oncology, Alexandria, VA.

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Classifications MeSH