Pertuzumab Plus Trastuzumab in Patients With Lung Cancer With
Journal
JCO precision oncology
ISSN: 2473-4284
Titre abrégé: JCO Precis Oncol
Pays: United States
ID NLM: 101705370
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
medline:
16
6
2023
pubmed:
14
6
2023
entrez:
14
6
2023
Statut:
ppublish
Résumé
The Targeted Agent and Profiling Utilization Registry Study is a pragmatic basket trial evaluating antitumor activity of commercially available targeted agents in patients with advanced cancers harboring potentially actionable genomic alterations. Data from a cohort of patients with lung cancer and Eligible patients had advanced lung cancer of any histology, no standard treatment options, measurable disease (RECIST v1.1), Eastern Cooperative Oncology Group performance status 0-2, adequate organ function, and tumors with Twenty-eight patients with lung cancer (27 non-small-cell, 1 small-cell) and Combination P + T showed evidence of antitumor activity in heavily pretreated patients with non-small-cell lung cancer and
Substances chimiques
Antineoplastic Agents
0
ERBB2 protein, human
EC 2.7.10.1
pertuzumab
K16AIQ8CTM
Receptor, ErbB-2
EC 2.7.10.1
Trastuzumab
P188ANX8CK
Banques de données
ClinicalTrials.gov
['NCT02693535']
Types de publication
Journal Article
Pragmatic Clinical Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM