Diffuse fasciitis with eosinophilia in boys: a case-based review.
Clinical presentation of eosinophilic fasciitis
Diffuse fasciitis with eosinophilia
Eosinophilic fasciitis in children
Hypercalcemia
Journal
Rheumatology international
ISSN: 1437-160X
Titre abrégé: Rheumatol Int
Pays: Germany
ID NLM: 8206885
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
received:
27
02
2023
accepted:
05
06
2023
medline:
17
7
2023
pubmed:
15
6
2023
entrez:
14
6
2023
Statut:
ppublish
Résumé
Diffuse fasciitis with eosinophilia (EF) is a rare condition classified as a part of the connective tissue disorders. The clinical presentation of this condition can be diverse, however the main symptoms include symmetrical swelling and hardening of distal parts of limbs accompanied by peripheral eosinophilia. The diagnostic criteria are not specified. In inconclusions cases Magnetic Resonance Imaging (MRI) and skin to muscle biopsy may be useful. The pathogenesis and ethiology remain unknown, but extensive physical exertion, certain infectious factors, such as Borrelia burgdorferi, or medications may serve as a trigger. EF affects equally women and men, mainly in their middle age, however the disease can occur at any age. The standard therapy contents gluccocorticosteroids. As a second-line treatment, methotrexate is usually chosen. In this article we compare world reports of EF in paediatric patients with the cases of two adolescent male patients recently hospitalized in the Department of Paediatric Rheumatology.
Identifiants
pubmed: 37316632
doi: 10.1007/s00296-023-05362-x
pii: 10.1007/s00296-023-05362-x
pmc: PMC10348932
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1755-1764Informations de copyright
© 2023. The Author(s).
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