Dedicated macrophages organize and maintain the enteric nervous system.

Enteric Nervous System / cytology Intestines / innervation Lymphotoxin-alpha / metabolism Macrophages / metabolism Neurons / physiology Weaning Cell Communication Transcriptome Phenotype Phagocytosis Synapses Neuronal Plasticity Gastrointestinal Transit

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 23 08 2022
accepted: 11 05 2023
medline: 23 6 2023
pubmed: 15 6 2023
entrez: 14 6 2023
Statut: ppublish

Résumé

Correct development and maturation of the enteric nervous system (ENS) is critical for survival

Identifiants

DOI: 10.1038/s41586-023-06200-7 PMID: 37316669
pubmed: 37316669
doi: 10.1038/s41586-023-06200-7
pii: 10.1038/s41586-023-06200-7
doi:

Substances chimiques

Lymphotoxin-alpha 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

818-826

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Maria Francesca Viola (MF)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
ORCID: 0000-0003-0660-9506

Marta Chavero-Pieres (M)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
ORCID: 0000-0003-1116-8397

Elodie Modave (E)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.

Marcello Delfini (M)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
ORCID: 0000-0003-0342-5445

Nathalie Stakenborg (N)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
ORCID: 0000-0002-6229-0045

Maria Cuende Estévez (MC)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.

Naomi Fabre (N)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.

Iris Appeltans (I)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.

Tobie Martens (T)

Laboratory for Enteric NeuroScience, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
ORCID: 0000-0003-4966-5591

Katy Vandereyken (K)

Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
KU Leuven Institute for Single Cell Omics, KU Leuven, Leuven, Belgium.

Hannah Theobald (H)

Quantitative Systems Biology, LIMES-Institute, University of Bonn, Bonn, Germany.
ORCID: 0000-0003-4580-5542

Jens Van Herck (J)

Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
ORCID: 0000-0002-1291-4462

Philippe Petry (P)

Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Faculty of Biology, University of Freiburg, Freiburg, Germany.

Simon Verheijden (S)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
Janssen Research and Development, Janssen Pharmaceutica NV, Beerse, Belgium.

Sebastiaan De Schepper (S)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
UK Dementia Research Institute, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.

Alejandro Sifrim (A)

KU Leuven Institute for Single Cell Omics, KU Leuven, Leuven, Belgium.
Laboratory of Multi-Omic Integrative Bioinformatics, Department of Genetics, KU Leuven, Leuven, Belgium.
Leuven AI Institute, KU Leuven, Leuven, Belgium.

Zhaoyuan Liu (Z)

Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Florent Ginhoux (F)

Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Singapore Immunology Network, Agency for Science, Technology & Research, Singapore, Singapore.
Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
ORCID: 0000-0002-2857-7755

Mohamad Azhar (M)

Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC, USA.
ORCID: 0000-0001-9228-8096

Andreas Schlitzer (A)

Quantitative Systems Biology, LIMES-Institute, University of Bonn, Bonn, Germany.

Gianluca Matteoli (G)

Laboratory for Mucosal Immunology, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
ORCID: 0000-0002-2902-4976

Katrin Kierdorf (K)

Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0002-9272-4780

Marco Prinz (M)

Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0002-0349-1955

Pieter Vanden Berghe (P)

Laboratory for Enteric NeuroScience, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
ORCID: 0000-0002-0009-2094

Thierry Voet (T)

Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
KU Leuven Institute for Single Cell Omics, KU Leuven, Leuven, Belgium.
ORCID: 0000-0003-1204-9963

Guy Boeckxstaens (G)

Laboratory for Intestinal Neuro-Immune Interaction, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium. guy.boeckxstaens@kuleuven.be.
KU Leuven Institute for Single Cell Omics, KU Leuven, Leuven, Belgium. guy.boeckxstaens@kuleuven.be.
ORCID: 0000-0001-8267-5797

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Classifications MeSH

questionsmedicales.fr › Système nerveux › Système nerveux périphérique › Système nerveux autonome › Système nerveux entérique › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Système digestif › Tube digestif › Intestins › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Facteurs de nécrose tumorale › Lymphotoxine alpha › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Cellules › Neurones › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Sevrage › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Communication cellulaire › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Transcriptome › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Phénomènes du système immunitaire › Phagocytose › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Structures de la membrane cellulaire › Jonctions intercellulaires › Synapses › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Plasticité neuronale › Dedicated macrophages organize and maintain...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Motilité gastrointestinale › Transit gastrointestinal › Dedicated macrophages organize and maintain...